Overview

What is atrial fibrillation?

Atrial fibrillation (AFib) is an irregular, rapid heartbeat that can cause unpleasant symptoms and potentially lead to heart failure. It is the most common type of arrhythmia. AFib is rare in children, but it is becoming more prevalent in older adults, especially those who have congenital heart disease (CHD). AFib episodes can be short and resolve on their own, or they can persist and require treatment.

Depending on its severity, AFib can be treated several ways, including lifestyle changes, medication, cardioversion therapy, and a cardiac catheterization procedure known as catheter ablation. Boston Children’s Division of Electrophysiology specializes in diagnosing and treating AFib — including with a new minimally invasive pulse-field ablation procedure that safely treats patients and allows them to quickly recover and lead healthy, active lives.

Symptoms & Causes

What are the symptoms of AFib?

Some people may have AFib but experience no symptoms or not know they have the condition. When AFib symptoms do occur, they may include:

  • An irregular heartbeat
  • Heart palpitations (fast, fluttering, or a pounding heartbeat)
  • Shortness of breath
  • Chest pain
  • Lightheadedness, dizziness, or fainting
  • Fatigue and weakness

What causes AFib?

AFib happens when the electrical system in the heart’s upper chambers (the atria) isn’t functioning properly. Certain heart muscle cells may become “excitable” and rapidly activate, causing the atria to fibrillate (quiver). These triggering beats often originate in the pulmonary veins that drain oxygen-rich blood from the lungs to the left atrium. The quivering atria sends too many electrical signals to the heart’s lower chambers (the ventricles), causing them to beat irregularly and rapidly. The presence of conditions that commonly affect CHD patients as they age — scar tissue, increased blood pressure, enlargement (dilation) of the atria — can increase the risk of AFib.

Other risk factors include:

  • Heart muscle disease (cardiomyopathy)
  • Heart valve disease
  • High blood pressure (hypertension)
  • Narrowed and blocked heart arteries
  • Post-surgery complications
  • Lung diseases and infections such as pneumonia
  • Obesity
  • Tobacco and alcohol use

How does AFib affect the heart?

When the heart beats rapidly, the ventricles can’t collect and pump blood normally. This can decrease the function of the ventricles and cause fluid buildup in the lungs or body. Blood clots can form in the atria because they aren’t squeezing properly, potentially leading to a stroke.

Diagnosis & Treatments

How is AFib diagnosed?

A cardiologist can detect and diagnose AFib through a physical examination and by studying a patient’s medical history. An AFib diagnosis can also be determined through testing that includes an:

How is AFib treated?

The type of treatment depends on how long a patient has had AFib and its severity. But the goal is the same: reset the heart’s rhythm and ensure blood circulates properly.

Medication and lifestyle changes

A cardiologist may prescribe medications that control the heart’s beating and prevent blood clotting. They may also recommend lifestyle changes such as weight loss, stress reduction, avoidance of tobacco and alcohol, and treatment of sleep apnea.

Cardioversion therapy

If an AFib episode persists and causes intolerable symptoms or heart failure, cardioversion therapy might be recommended. Performed in a hospital, cardioversion therapy resets the heart’s rhythm — either with medicine or by an electric shock delivered through patches or paddles that are placed on the chest.

Anti-arrhythmic medications

Heart rhythm medications may be prescribed for patients with frequent AFib episodes. Some of these medications may simply slow down the heart rate to avoid rapid heart rates during AFib episodes. Stronger medications may alter the electrical properties of the heart muscle to prevent episodes from occurring at all. Some patients may experience side effects from these medications, and some medications require hospitalization for monitoring during their first few doses.

Catheter ablation

Catheter ablation is a procedure performed in a cardiac catheterization lab. There are several types of catheter ablation, though all have the same goal of eliminating the heart tissue responsible for the arrhythmia being treated. Traditionally, ablation is accomplished using either radiofrequency (heating) or cryothermal (freezing) energy. Although serious complications are rare, these types of ablation could damage the esophagus or phrenic nerve (which controls the actions of the diaphragm), or they may cause pulmonary vein stenosis.

Pulsed-field ablation

Boston Children’s specializes in a type of catheter ablation that is minimally invasive and has been shown to reduce risk: pulsed-field ablation (PFA). With a catheter, PFA delivers a targeted, high-voltage electric field to heart muscle cells causing arrhythmia. The electric field pulses eliminate the cells by creating pores in heart cell membranes without heating or freezing. This technology is widely used in the treatment of adults with AFib without CHD and drastically reduces the risks of damage to the esophagus, phrenic nerve, and pulmonary veins compared to traditional ablation energy procedures.

Electrophysiologists first try PFA on pulmonary veins that are causing AFib. Known as pulmonary vein isolation, this step creates scar tissue around pulmonary vein openings to block the faulty electrical signals. But many people with AFib need additional ablation, especially if there is dilation (stretching) or pre-existing scarring in the atria. PFA technology delivers larger and faster applications than traditional heating and freezing ablation, making the procedure shorter than others and requiring less time under anesthesia. Also, by causing less inflammation and pain than other types of cardiac ablation, PFA usually leads to quick recoveries; patients typically go home the same day or stay in the hospital one night for care and observation.

Pacemaker

A pacemaker is a small battery-powered device that is placed under the skin and monitors the heart’s rhythm. If the heart beats too slow, the pacemaker can send electrical signals to increase the heart rate to normal levels.

Implantable cardioverter defibrillator (ICD)

Like a pacemaker, an ICD is small and placed under the skin. It also senses if the heart is beating fast and will deliver an electrical shock to the heart to restore normal rhythm.

How we care for atrial fibrillation at Boston Children’s

Pulsed-field ablation is an example of how our electrophysiology team is always improving AFib treatment outcomes while minimizing complications and risk. Studies show that AFib is likely to increase in CHD patients as they continue to get older. We expect PFA to set a new standard in AFib care as we treat more patients: a treatment that is safer and more effective than other types of catheter ablation.