Brian Kalish, MD

Director, Neuroprotection and Neuroplasticity Program; Associate Medical Director, Critical Care Transport Program

Assistant Professor of Pediatrics, Harvard Medical School

NPI 1184967192

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Brian Kalish, MD

Director, Neuroprotection and Neuroplasticity Program; Associate Medical Director, Critical Care Transport Program

Assistant Professor of Pediatrics, Harvard Medical School

Medical Services

Languages

English

Education

Undergraduate School

Johns Hopkins University

Baltimore

Medical School

Harvard Medical School

Boston

Residency

Pediatrics

Boston Combined Residency Program (BCRP)

Boston

Fellowship

Harvard Program in Neonatal-Perinatal Medicine

Boston

Certifications

American Board of Pediatrics (General)

American Board of Pediatrics (Neonatal-Perinatal Medicine)

Professional History

Dr. Brian Kalish is a neonatologist and neurobiologist and serves as the Director of the Program in Neonatal Neuroprotection and Neuroplasticity. Dr. Kalish studied Public Health at Johns Hopkins and completed medical school at Harvard. After residency in the Boston Combined Program in Pediatrics on the Accelerated Research Pathway, he completed fellowship in the Harvard Program in Neonatal-Perinatal Medicine. Dr. Kalish was a Staff Neonatologist, Director of Neonatology Research, and Scientist in the Program in Neuroscience and Mental Health at the Hospital for Sick Children before returning to Boston Children's Hospital in 2024. His clinical expertise is in neonatal neuroscience and his research focuses on understanding mechanisms and developing new therapies for fetal and neonatal brain injury. Dr. Kalish also serves as Associate Medical Director of the Critical Care Transport Team.

Publications

Postnatal management of preterm infants with congenital diaphragmatic hernia. View Abstract

Neonatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography. View Abstract

Automated Neuroprognostication Via Machine Learning in Neonates with Hypoxic-Ischemic Encephalopathy. View Abstract

Remote ischemic post-conditioning for neonatal encephalopathy: a safety and feasibility trial. View Abstract

Prognostic Indicators of Reorientation of Care in Perinatal Hypoxic-Ischemic Encephalopathy Spectrum. View Abstract

Blood product transfusion practices in neonates with hypoxic-ischemic encephalopathy. View Abstract

Fetal hypoplastic lungs have multilineage inflammation that is reversed by amniotic fluid stem cell extracellular vesicle treatment. View Abstract

Early human fetal lung atlas reveals the temporal dynamics of epithelial cell plasticity. View Abstract

Translating regenerative medicine therapies in neonatal necrotizing enterocolitis. View Abstract

Small but mighty: the rise of microprotein biology in neuroscience. View Abstract

Proceedings of the 15th International Newborn Brain Conference: Neuroprotection strategies in the neonate. View Abstract

Neonatal Hypoxic-Ischemic Encephalopathy Spectrum: Severity-Stratified Analysis of Neuroimaging Modalities and Association with Neurodevelopmental Outcomes. View Abstract

Single-Nucleus Profiling Identifies Accelerated Oligodendrocyte Precursor Cell Senescence in a Mouse Model of Down Syndrome. View Abstract

?-Protocadherins control synapse formation and peripheral branching of touch sensory neurons. View Abstract

Neurodevelopmental outcomes after neonatal surgery. View Abstract

Developmental dynamics of RNA translation in the human brain. View Abstract

The Genomic Architecture of Pregnancy-Associated Plasticity in the Maternal Mouse Hippocampus. View Abstract

ECI Biocommentary: Brian T. Kalish. View Abstract

Repetitive Mild Closed Head Injury in Adolescent Mice Is Associated with Impaired Proteostasis, Neuroinflammation, and Tauopathy. View Abstract

Subclinical Electrographic Seizures in the Newborn-Is More Treatment Better? View Abstract

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation. View Abstract

Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice. View Abstract

Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension. View Abstract

Single-cell immunophenotyping of the fetal immune response to maternal SARS-CoV-2 infection in late gestation. View Abstract

Maternal immune activation in mice disrupts proteostasis in the fetal brain. View Abstract

The impact of maternal obesity on childhood neurodevelopment. View Abstract

Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study. View Abstract

Single-nucleus RNA sequencing of mouse auditory cortex reveals critical period triggers and brakes. View Abstract

Factors Associated With Mortality in Children Who Successfully Wean From Extracorporeal Membrane Oxygenation. View Abstract

Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement. View Abstract

Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling. View Abstract

Single-cell transcriptomics of the developing lateral geniculate nucleus reveals insights into circuit assembly and refinement. View Abstract

Sonographic Pulmonary Abnormalities in Fetuses With Hypoplastic Left Heart Syndrome and Intact Atrial Septum Undergoing Attempted Atrial Septostomy In Utero. View Abstract

Management of Neonatal Hypotension. View Abstract

Association of Extracorporeal Membrane Oxygenation Support Adequacy and Residual Lesions With Outcomes in Neonates Supported After Cardiac Surgery. View Abstract

Assessment of Progressive Pathophysiology After Early Prenatal Diagnosis of the Ebstein Anomaly or Tricuspid Valve Dysplasia. View Abstract

Weight Drop Models in Traumatic Brain Injury. View Abstract

The Impact of Institutional Review Boards (IRBs) on Clinical Innovation: A Survey of Investigators and IRB Members. View Abstract

Clinically Relevant Mechanisms of Lipid Synthesis, Transport, and Storage. View Abstract

Outcomes and Predictors of Perinatal Mortality in Fetuses With Ebstein Anomaly or Tricuspid Valve Dysplasia in the Current Era: A Multicenter Study. View Abstract

Dietary ?-3 fatty acids protect against vasculopathy in a transgenic mouse model of sickle cell disease. View Abstract

Associations of prenatal maternal blood mercury concentrations with early and mid-childhood blood pressure: a prospective study. View Abstract

Perinatal and infant outcomes of prenatal diagnosis of heterotaxy syndrome (asplenia and polysplenia). View Abstract

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. View Abstract

Takedown of cavopulmonary shunt at biventricular repair. View Abstract

Technical challenges of atrial septal stent placement in fetuses with hypoplastic left heart syndrome and intact atrial septum. View Abstract

Reply to letter: "Prehospital intravenous fluid administration is associated with higher mortality in trauma patients". View Abstract

Docosahexaenoic acid, G protein-coupled receptors, and melanoma: is G protein-coupled receptor 40 a potential therapeutic target? View Abstract

Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators. View Abstract

Biventricular conversion after single ventricle palliation in patients with small left heart structures: short-term outcomes. View Abstract

Epoxyeicosanoids promote organ and tissue regeneration. View Abstract

The growing role of eicosanoids in tissue regeneration, repair, and wound healing. View Abstract

A.S.P.E.N. clinical guidelines: nutrition support of neonatal patients at risk for metabolic bone disease. View Abstract

A metabolomic analysis of two intravenous lipid emulsions in a murine model. View Abstract

The role of the ?-3 fatty acid DHA in the human life cycle. View Abstract

The effect of varying ratios of docosahexaenoic acid and arachidonic acid in the prevention and reversal of biochemical essential fatty acid deficiency in a murine model. View Abstract

Quality assessment in pancreatic surgery: what might tomorrow require? View Abstract

Dietary fish oil aggravates paracetamol-induced liver injury in mice. View Abstract

A tutorial on fatty acid biology. View Abstract

HIV testing in emergency departments in the United States: a national survey. View Abstract

Operational methods of HIV testing in emergency departments: a systematic review. View Abstract

Prehospital intravenous fluid administration is associated with higher mortality in trauma patients: a National Trauma Data Bank analysis. View Abstract

Serial amnioinfusions prevent fetal pulmonary hypoplasia in a large animal model of oligohydramnios. View Abstract

Systematic review and meta-analysis of steatosis as a risk factor in major hepatic resection. View Abstract

Spine immobilization in penetrating trauma: more harm than good? View Abstract

National survey of Laboratory Response Network sentinel laboratory preparedness. View Abstract

Population immunity to measles virus and the effect of HIV-1 infection after a mass measles vaccination campaign in Lusaka, Zambia: a cross-sectional survey. View Abstract

Update on emerging infections: news from the Centers for Disease Control and Prevention. False-positive oral fluid rapid HIV tests--New York City, 2005-2008. View Abstract

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