Jonathan Mansbach, MD, MPH

Associate Chief, Division of General Pediatrics; Chief, Hospital Medicine

Associate Professor, Harvard Medical School

Phone 617-355-7584

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NPI 1780761312

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Jonathan Mansbach, MD, MPH

Associate Chief, Division of General Pediatrics; Chief, Hospital Medicine

Associate Professor, Harvard Medical School

Medical Services

Languages

English

Education

Undergraduate School

Haverford College

1991

Haverford

Graduate School

Duke University School of Medicine

Durham

Graduate School

MPH

Harvard School of Public Health

Boston

Medical School

Duke University School of Medicine

1996

Durham

Internship

Pediatrics

Boston Combined Residency Program (BCRP)

1997

Boston

Residency

Pediatrics

Boston Combined Residency Program (BCRP)

1999

Boston

Fellowship

Combined Fellowship in Adolescent and Division of General Pediatrics

Boston Children's Hospital

2002

Boston

Certifications

American Board of Pediatrics (General)

American Board of Pediatrics (Pediatric Hospital Medicine)

American Board of Pediatrics (Adolescent Medicine)

Professional History

Jonathan Mansbach, MD, MPH graduated from Haverford College, taught biology and chemistry for one year, and then went to Duke Medical School. He has been at Boston Children’s ever since -- as a resident, fellow, and now faculty. His fellowship was a combined program in adolescent and hospitalist medicine. After fellowship, he obtained a Masters of Public Health from the Harvard School of Public Health. Currently, he spends much of his time conducting translational research examining bronchiolitis, respiratory viruses, the respiratory microbiome, and the transition from bronchiolitis to asthma. He has had grant funding from foundations and the NIH to investigate these areas.

Publications

Pediatric Mental Health Boarding: 2017 to 2023. View Abstract

Nirsevimab decreased the subsequent risk of respiratory syncytial virus infection and wheezing in the 2023-2024 RSV season. View Abstract

Increasing Incidence of Serious Head and Neck Infections among Children in the United States, 2018-2023. View Abstract

Integrated nasopharyngeal airway metagenome and asthma genetic risk endotyping of severe bronchiolitis in infancy and risk of childhood asthma. View Abstract

Integrated-omics analysis with explainable deep networks on pathobiology of infant bronchiolitis. View Abstract

Influenza and COVID-19 Vaccination Rates Among Children Receiving Long-Term Ventilation. View Abstract

Nasal microRNA signatures for disease severity in infants with respiratory syncytial virus bronchiolitis: a multicentre prospective study. View Abstract

Race-Neutral Equations and Pulmonary Function Test Interpretation in Two Pediatric Cohorts. View Abstract

Misclassification of Both Influenza Infection and Oseltamivir Exposure Status in Administrative Data. View Abstract

Trends in emergency department visits for bronchiolitis, 1993-2019. View Abstract

Respiratory Virus-Specific Nasopharyngeal Lipidome Signatures and Severity in Infants With Bronchiolitis: A Prospective Multicenter Study. View Abstract

Questionable Safety of Proton Pump Inhibitor Use in Children. View Abstract

Association between severe bronchiolitis in infancy and age 6-year lung function. View Abstract

Nasopharyngeal fungal subtypes of infant bronchiolitis and disease severity risk. View Abstract

Association between Early Childhood Vitamin D Status and Age 6-Year Lung Function among Children with a History of Severe Bronchiolitis in Infancy. View Abstract

Factors associated with mild bronchiolitis in young infants. View Abstract

Immunoglobulin E-virus phenotypes of infant bronchiolitis and risk of childhood asthma. View Abstract

Recurrent wheezing phenotypes after severe bronchiolitis and progression to asthma. View Abstract

Integrated relationship of nasopharyngeal airway host response and microbiome associates with bronchiolitis severity. View Abstract

Association of Nasopharyngeal and Serum Glutathione Metabolism with Bronchiolitis Severity and Asthma Risk: A Prospective Multicenter Cohort Study. View Abstract

Nasopharyngeal metatranscriptome profiles of infants with bronchiolitis and risk of childhood asthma: a multicentre prospective study. View Abstract

Total immunoglobulin E in infant bronchiolitis and risk of developing asthma. View Abstract

Airway Bacterial Colonization, Biofilms and Blooms, and Acute Respiratory Infection. View Abstract

Proteomics endotyping of infants with severe bronchiolitis and risk of childhood asthma. View Abstract

COVID-19-Associated Croup in Children. View Abstract

Nasopharyngeal airway dual-transcriptome of infants with severe bronchiolitis and risk of childhood asthma: A multicenter prospective study. View Abstract

Confirming racial/ethnic disparities in the management of severe bronchiolitis. View Abstract

Bacterial Signatures of Paediatric Respiratory Disease: An Individual Participant Data Meta-Analysis. View Abstract

Role of nasal microbiota and host response in infants with respiratory syncytial virus infection: Causal questions about respiratory outcomes. View Abstract

Serum Soluble Receptor for Advanced Glycation End Products in Infants With Bronchiolitis: Associations With Acute Severity and Recurrent Wheeze. View Abstract

Severe bronchiolitis profiles and risk of asthma development in Finnish children. View Abstract

Late Pre-term Infants with Severe Bronchiolitis and Risk of Asthma by Age 5 Years. View Abstract

Urinary Tract Infections in Children with Vesicoureteral Reflux Are Accompanied by Alterations in Urinary Microbiota and Metabolome Profiles. View Abstract

Proteome signature difference between respiratory viruses is associated with severity of bronchiolitis. View Abstract

Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma. View Abstract

Utility of Inflammatory Markers in Hospitalized Children With Skin Erythema. View Abstract

Integrated associations of nasopharyngeal and serum metabolome with bronchiolitis severity and asthma: A multicenter prospective cohort study. View Abstract

Detection of Respiratory Syncytial Virus or Rhinovirus Weeks After Hospitalization for Bronchiolitis and the Risk of Recurrent Wheezing. View Abstract

A joint modeling approach for longitudinal microbiome data improves ability to detect microbiome associations with disease. View Abstract

Integrated-omics endotyping of infants with rhinovirus bronchiolitis and risk of childhood asthma. View Abstract

Pediatric Hospitalizations During the COVID-19 Pandemic. View Abstract

A comparison of childhood asthma case definitions based on parent-reported data. View Abstract

Association of endemic coronaviruses with nasopharyngeal metabolome and microbiota among infants with severe bronchiolitis: a prospective multicenter study. View Abstract

Being Mindful About Follow-up Care After Pediatric Hospitalization for Bronchiolitis. View Abstract

Machine learning-based prediction of acute severity in infants hospitalized for bronchiolitis: a multicenter prospective study. View Abstract

Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study. View Abstract

Severe Coronavirus Bronchiolitis in the Pre-COVID-19 Era. View Abstract

Association of rhinovirus species with nasopharyngeal metabolome in bronchiolitis infants: A multicenter study. View Abstract

In infants with severe bronchiolitis: dual-transcriptomic profiling of nasopharyngeal microbiome and host response. View Abstract

Increased Moraxella and Streptococcus species abundance after severe bronchiolitis is associated with recurrent wheezing. View Abstract

Trends in Bronchiolitis Hospitalizations in the United States: 2000-2016. View Abstract

Bronchiolitis severity is related to recurrent wheezing by age 3 years in a prospective, multicenter cohort. View Abstract

Respiratory Virus Epidemiology Among US Infants With Severe Bronchiolitis: Analysis of 2 Multicenter, Multiyear Cohort Studies. View Abstract

Association of respiratory viruses with serum metabolome in infants with severe bronchiolitis. View Abstract

Association of Serum Albumin With Apnea in Infants With Bronchiolitis: A Secondary Analysis of Data From the MARC-35 Study. View Abstract

Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze. View Abstract

Serum Metabolome Is Associated With the Nasopharyngeal Microbiota and Disease Severity Among Infants With Bronchiolitis. View Abstract

Haemophilus-Dominant Nasopharyngeal Microbiota Is Associated With Delayed Clearance of Respiratory Syncytial Virus in Infants Hospitalized for Bronchiolitis. View Abstract

Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland. View Abstract

Association of type 2 cytokines in severe rhinovirus bronchiolitis during infancy with risk of developing asthma: A multicenter prospective study. View Abstract

Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis. View Abstract

Circulating 25-hydroxyvitamin D, nasopharyngeal microbiota, and bronchiolitis severity. View Abstract

Tracheal Microbiota in Patients With a Tracheostomy Before, During and After an Acute Respiratory Infection. View Abstract

Vitamin D Status at the Time of Hospitalization for Bronchiolitis and Its Association with Disease Severity. View Abstract

Severe bronchiolitis profiles and risk of recurrent wheeze by age 3 years. View Abstract

Overcoming the Bronchiolitis Blues: Embracing Global Collaboration and Disease Heterogeneity. View Abstract

Nasopharyngeal CCL5 in infants with severe bronchiolitis and risk of recurrent wheezing: A multi-center prospective cohort study. View Abstract

Serum 25-hydroxyvitamin D, metabolome, and bronchiolitis severity among infants-A multicenter cohort study. View Abstract

Multicenter Study of Albuterol Use Among Infants Hospitalized with Bronchiolitis. View Abstract

Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways. View Abstract

Circulating 25-hydroxyvitamin D, nasopharyngeal airway metabolome, and bronchiolitis severity. View Abstract

RSV vs. rhinovirus bronchiolitis: difference in nasal airway microRNA profiles and NF?B signaling. View Abstract

The association between anterior nares and nasopharyngeal microbiota in infants hospitalized for bronchiolitis. View Abstract

Nasal Airway Microbiota Profile and Severe Bronchiolitis in Infants: A Case-control Study. View Abstract

Associations of Nasopharyngeal Metabolome and Microbiome with Severity among Infants with Bronchiolitis. A Multiomic Analysis. View Abstract

Serum LL-37 Levels Associated With Severity of Bronchiolitis and Viral Etiology. View Abstract

The temporal dynamics of the tracheal microbiome in tracheostomised patients with and without lower respiratory infections. View Abstract

Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis. View Abstract

Multicenter Observational Study of the Use of Nebulized Hypertonic Saline to Treat Children Hospitalized for Bronchiolitis From 2008 to 2014. View Abstract

Sphingolipid metabolism potential in fecal microbiome and bronchiolitis in infants: a case-control study. View Abstract

The relationship between nasopharyngeal CCL5 and microbiota on disease severity among infants with bronchiolitis. View Abstract

Household siblings and nasal and fecal microbiota in infants. View Abstract

Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis. View Abstract

Association of nasopharyngeal microbiota profiles with bronchiolitis severity in infants hospitalised for bronchiolitis. View Abstract

The Fecal Microbiota Profile and Bronchiolitis in Infants. View Abstract

A clustering approach to identify severe bronchiolitis profiles in children. View Abstract

Trends in Infectious Disease Hospitalizations in US Children, 2000 to 2012. View Abstract

Respiratory syncytial virus and rhinovirus severe bronchiolitis are associated with distinct nasopharyngeal microbiota. View Abstract

Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics. View Abstract

Detection of respiratory syncytial virus and rhinovirus in healthy infants. View Abstract

Prenatal Versus Postnatal Tobacco Smoke Exposure and Intensive Care Use in Children Hospitalized With Bronchiolitis. View Abstract

Clinical Endpoints for Respiratory Syncytial Virus Prophylaxis Trials in Infants and Children in High-income and Middle-income Countries. View Abstract

Eligibility for palivizumab prophylaxis in a cohort of children with severe bronchiolitis. View Abstract

Association Between Hyponatremia and Higher Bronchiolitis Severity Among Children in the ICU With Bronchiolitis. View Abstract

Bordetella pertussis is an uncommon pathogen in children hospitalized with bronchiolitis during the winter season. View Abstract

Use of Cough and Cold Medications in Severe Bronchiolitis before and after a Health Advisory Warning against Their Use. View Abstract

Variability of intensive care management for children with bronchiolitis. View Abstract

Rhinovirus-induced bronchiolitis: Lack of association between virus genomic load and short-term outcomes. View Abstract

Hospital course and discharge criteria for children hospitalized with bronchiolitis. View Abstract

Risk factors for requiring intensive care among children admitted to ward with bronchiolitis. View Abstract

Respiratory syncytial virus genomic load and disease severity among children hospitalized with bronchiolitis: multicenter cohort studies in the United States and Finland. View Abstract

Variability in inpatient management of children hospitalized with bronchiolitis. View Abstract

Hospital length-of-stay is associated with rhinovirus etiology of bronchiolitis. View Abstract

Multicenter study of viral etiology and relapse in hospitalized children with bronchiolitis. View Abstract

Racial/ethnic differences in the presentation and management of severe bronchiolitis. View Abstract

Recent evidence on the management of bronchiolitis. View Abstract

Infectious pathogens and bronchiolitis outcomes. View Abstract

Temporal trends in emergency department visits for bronchiolitis in the United States, 2006 to 2010. View Abstract

Nasopharyngeal Proteobacteria are associated with viral etiology and acute wheezing in children with severe bronchiolitis. View Abstract

Apnea in children hospitalized with bronchiolitis. View Abstract

Trends in bronchiolitis hospitalizations in the United States, 2000-2009. View Abstract

Altitude and environmental climate effects on bronchiolitis severity among children presenting to the emergency department. View Abstract

Serum cathelicidin level is associated with viral etiology and severity of bronchiolitis. View Abstract

Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation. View Abstract

Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis. View Abstract

Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study. View Abstract

National study of antibiotic use in emergency department visits for pneumonia, 1993 through 2008. View Abstract

Serum 25-hydroxyvitamin D levels among Boston trainee doctors in winter. View Abstract

Clinical features can help predict which infants with bronchiolitis will need hospital admission. View Abstract

Low serum 25-hydroxyvitamin D levels are associated with increased risk of viral coinfections in wheezing children. View Abstract

Insurance status and the variable management of children presenting to the emergency department with bronchiolitis. View Abstract

Prospective multicenter study of bronchiolitis: predictors of an unscheduled visit after discharge from the emergency department. View Abstract

Vitamin D insufficiency in pregnant and nonpregnant women of childbearing age in the United States. View Abstract

Respiratory viruses in bronchiolitis and their link to recurrent wheezing and asthma. View Abstract

Serum 25-hydroxyvitamin D levels among US children aged 1 to 11 years: do children need more vitamin D? View Abstract

Factors associated with longer emergency department length of stay for children with bronchiolitis : a prospective multicenter study. View Abstract

Variability in the diagnostic labeling of nonbacterial lower respiratory tract infections: a multicenter study of children who presented to the emergency department. View Abstract

Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey. View Abstract

Vitamin D, respiratory infections, and asthma. View Abstract

Prospective multicenter bronchiolitis study: predicting intensive care unit admissions. View Abstract

Bronchiolitis: lingering questions about its definition and the potential role of vitamin D. View Abstract

Variations in admission practices for adolescents with anorexia nervosa: a North American sample. View Abstract

Prospective multicenter study of bronchiolitis: predicting safe discharges from the emergency department. View Abstract

Prospective multicenter study of the viral etiology of bronchiolitis in the emergency department. View Abstract

US outpatient office visits for bronchiolitis, 1993-2004. View Abstract

Evaluation of compliance with palivizumab recommendations in a multicenter study of young children presenting to the emergency department with bronchiolitis. View Abstract

Variation in IRB responses to a standard, observational pediatric research protocol View Abstract

Variation in institutional review board responses to a standard, observational, pediatric research protocol. View Abstract

Evidence Based Medicine View Abstract

U.S. Outpatient office visits for bronchiolitis, 1993-2004 View Abstract

Direct medical costs of bronchiolitis hospitalizations in the United States. View Abstract

Multicenter Study of Bronchiolitis in the Emergency Department View Abstract

Testicular torsion and risk factors for orchiectomy. View Abstract

Bronchiolitis in US emergency departments 1992 to 2000: epidemiology and practice variation. View Abstract

Variation in Admission for Adolescents with Anorexia Nervosa: A North American Sample View Abstract

Two children with Lyme disease presenting with persistent headache. Pediatrics. 2003; 112: e477-e479. Reprinted in Review Series Neurology View Abstract

Lyme disease presenting with persistent headache. View Abstract

Which psychiatric patients board on the medical service? View Abstract

A practical guide to prescribing oral contraceptives View Abstract

Optimizing the care of hospitalized youth View Abstract

Demystifying delayed puberty View Abstract

New seizures in a 6 year-old: Expanding Horizons View Abstract

Phenobarbital selectively promotes initiated cells with reduced TGF beta receptor levels. View Abstract

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