Joseph Gonzalez-Heydrich, MD

Senior Attending Psychiatrist, Department of Psychiatry and Behavioral Sciences
Associate Professor of Psychiatry, Harvard Medical School
Image
Joseph Gonzalez-Heydrich, MD

Joseph Gonzalez-Heydrich, MD

Senior Attending Psychiatrist, Department of Psychiatry and Behavioral Sciences
Associate Professor of Psychiatry, Harvard Medical School

Medical Services

Languages
English
Spanish
Education
Medical School
Johns Hopkins University School of Medicine
1986
Baltimore
MD
Residency
Stanford University
1990
Stanford
CA
Residency
Boston Children's Hospital
1995
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Psychiatry)
American Board of Psychiatry and Neurology (Child and Adolescent Psychiatry)
Professional History

Dr. Gonzalez serves as an expert for Psychology for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.

Publications

Reduced Cerebellar Volumes Associate with P300 Amplitude Attenuation in Children with Clinical High Risk for Psychosis and Early Onset Psychosis. View Abstract
The Impact of Childhood Maltreatment on Central Pain Processing in Individuals With Psychosis. View Abstract
Validation of an ICD-Code-Based Case Definition for Psychotic Illness Across Three Health Systems. View Abstract
Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis. View Abstract
Challenging Case: New-Onset Hallucinations and Developmental Regression in a Child with Autism Spectrum Disorder. View Abstract
Heterogeneity of clinical symptomatology in pediatric patients at clinical high risk for psychosis. View Abstract
Validation of an ICD-code-based case definition for psychotic illness across three health systems. View Abstract
Children with Early-Onset Psychosis Have Increased Burden of Rare GRIN2A Variants. View Abstract
Burden Experienced by Primary Caregivers of Children With Psychotic Disorders and at Clinical High Risk for Psychosis. View Abstract
16p13.11 deletion variants associated with neuropsychiatric disorders cause morphological and synaptic changes in induced pluripotent stem cell-derived neurons. View Abstract
Similar Rates of Deleterious Copy Number Variants in Early-Onset Psychosis and Autism Spectrum Disorder. View Abstract
Evaluation of a scalable online videogame-based biofeedback program to improve emotion regulation: A descriptive study assessing parent perspectives. View Abstract
Novel CAPN1 missense variants in complex hereditary spastic paraplegia with early-onset psychosis. View Abstract
Childhood maltreatment and its role in the development of pain and psychopathology. View Abstract
Association of Social Gaming with Well-Being (Escape COVID-19): A Sentiment Analysis. View Abstract
ITSN1: a novel candidate gene involved in autosomal dominant neurodevelopmental disorder spectrum. View Abstract
A "Proof of Concept" Randomized Controlled Trial of a Video Game Requiring Emotional Regulation to Augment Anger Control Training. View Abstract
Early role for a Na+,K+-ATPase (ATP1A3) in brain development. View Abstract
Underrepresentation of Phenotypic Variability of 16p13.11 Microduplication Syndrome Assessed With an Online Self-Phenotyping Tool (Phenotypr): Cohort Study. View Abstract
RCL1 copy number variants are associated with a range of neuropsychiatric phenotypes. View Abstract
P300 amplitude attenuation in high risk and early onset psychosis youth. View Abstract
Diagnostic Uncertainty in a Complex Young Man: Autism Versus Psychosis. View Abstract
De novo variant of TRRAP in a patient with very early onset psychosis in the context of non-verbal learning disability and obsessive-compulsive disorder: a case report. View Abstract
Young children with psychotic symptoms and risk for suicidal thoughts and behaviors: a research note. View Abstract
Social impairment and social language deficits in children and adolescents with and at risk for psychosis. View Abstract
De novo ATP1A3 and compound heterozygous NLRP3 mutations in a child with autism spectrum disorder, episodic fatigue and somnolence, and muckle-wells syndrome. View Abstract
Potentially traumatic events in youth with and at clinical high risk for psychosis. View Abstract
Suicidal behaviors and their relationship with psychotic-like symptoms in children and adolescents at clinical high risk for psychosis. View Abstract
Review of Salient Investigational Drugs for the Treatment of Fragile X Syndrome. View Abstract
Social cognitive impairment in 22q11 deletion syndrome: A review. View Abstract
A Developmental Perspective on Social-Cognition Difficulties in Youth at Clinical High Risk for Psychosis. View Abstract
Suicidal behaviors in children and adolescents with psychotic disorders. View Abstract
A novel de novo mutation in ATP1A3 and childhood-onset schizophrenia. View Abstract
Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports. View Abstract
N100 Repetition Suppression Indexes Neuroplastic Defects in Clinical High Risk and Psychotic Youth. View Abstract
Early auditory processing evoked potentials (N100) show a continuum of blunting from clinical high risk to psychosis in a pediatric sample. View Abstract
Neurophysiological differences between patients clinically at high risk for schizophrenia and neurotypical controls--first steps in development of a biomarker. View Abstract
Effect of 2 psychotherapies on depression and disease activity in pediatric Crohn's disease. View Abstract
Epilepsy & behavior: My intellectual home for 15 years! View Abstract
Comparing stimulant effects in youth with ADHD symptoms and epilepsy. View Abstract
Randomized efficacy trial of two psychotherapies for depression in youth with inflammatory bowel disease. View Abstract
"RAGE-Control": A Game to Build Emotional Strength. View Abstract
Management of psychotropic medication side effects in children and adolescents. View Abstract
Elevated rates of ADHD in mothers of children with comorbid ADHD and epilepsy. View Abstract
Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: a randomized, controlled, phase 2 trial. View Abstract
Longitudinal results of cognitive behavioral treatment for youths with inflammatory bowel disease and depressive symptoms. View Abstract
Evidence-based treatment approach to autism spectrum disorders. View Abstract
Tolerability of atomoxetine for treatment of pediatric attention-deficit/hyperactivity disorder in the context of epilepsy. View Abstract
The Use of Antiepileptic Drugs (AEDs) for the Treatment of Pediatric Aggression and Mood Disorders. View Abstract
Transcranial magnetic stimulation provides means to assess cortical plasticity and excitability in humans with fragile x syndrome and autism spectrum disorder. View Abstract
Adaptive phase I study of OROS methylphenidate treatment of attention deficit hyperactivity disorder with epilepsy. View Abstract
Use of a virtual community as a psychosocial support system in pediatric transplantation. View Abstract
Association between attention-deficit/hyperactivity disorder and epilepsy in pediatric populations. View Abstract
RAGE Control: Regulate and Gain Emotional Control. View Abstract
Linkage analysis of attention deficit hyperactivity disorder. View Abstract
Comparative clinical responses to risperidone and divalproex in patients with pediatric bipolar disorder. View Abstract
An expert opinion on methylphenidate treatment for attention deficit hyperactivity disorder in pediatric patients with epilepsy. View Abstract
Attention-deficit/hyperactivity disorder in pediatric patients with epilepsy: review of pharmacological treatment. View Abstract
Oxcarbazepine is no more effective than placebo for reducing manic symptoms of bipolar I disorder in children and adolescents. View Abstract
Tolerability of selective serotonin reuptake inhibitors in thirty-nine children under age seven: a retrospective chart review. View Abstract
Psychiatric disorders and behavioral characteristics of pediatric patients with both epilepsy and attention-deficit hyperactivity disorder. View Abstract
Prospective open-label pilot trial of mirtazapine in children and adolescents with social phobia. View Abstract
Pharmacological management of a youth with ADHD and a seizure disorder. View Abstract
A comparison of divalproex and oxcarbazepine in aggressive youth with bipolar disorder. View Abstract
Depression experience journal: a computer-based intervention for families facing childhood depression. View Abstract
A Comparison of Divalproex and Risperidone in Pediatric Bipolar Disorder View Abstract
Tolerability of Olanzapine and Ziprasidone in Youths with Bipolar Disorder View Abstract
Tolerability of OROS-MPH 18 mg, 36 mg, and 54 mg in Pediatric Epilepsy Plus Attention-Deficit/Hyperactivity Disorder (ADHD) View Abstract
Tolerability of OROS-MPH 18 mg, 36 mg, and 54 mg in Pediatric Epilepsy Plus Attention-Deficit Hyperactivity Disorder (ADHD) View Abstract
Tolerability of OROS-MPH 18 mg, 36 mg, and 54 mg in Pediatric Epilepsy Plus Attention-Deficit/Hyperactivity Disorder (ADHD) View Abstract
A Comparison of Divalproex and Oxcarbazepine in Aggressive Youth with Bipolar Disorder View Abstract
Antiepileptic Drugs (AEDs) in the Treatment of Aggression in Children and Adolescents View Abstract
Psychopharmacology View Abstract
Ziprasidone in Pediatric Patients: Efficacy and Tolerability View Abstract
Comparisons of Response to Stimulant Preparations in Pediatric Epilepsy View Abstract
Comparisons of Response to Stimulant Preparations in Pediatric Epilepsy View Abstract
A Comparison of Divalproex, Gabapentin, and Oxacarbazepine in Aggressive Youth View Abstract
Ziprasidone in Pediatric Patients: Efficacy and Tolerability View Abstract
No seizure exacerbation from risperidone in youth with comorbid epilepsy and psychiatric disorders: a case series. View Abstract
Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination. View Abstract
No Seizure Exacerbation from Ziprasidone in Youth with Comorbid Epilepsy and Psychiatric Disorders: A Case Series View Abstract
Comparison of Divalproex and Gabapentin: Effectiveness in Aggressive Youth View Abstract
An Open Trial of the Safety and Efficacy of Mirtazepine in Children and Adolescents with Social Phobia View Abstract
An Open Trial of the Safety and Efficacy of Mirtazapine in Children and Adolescents with Social Phobia View Abstract
Use of a computer-based application in a pediatric hemodialysis unit: a pilot study. View Abstract
Depression Experience Journal: A computer-based intervention for families facing childhood depression. Available online: http://www.experiencejournal.com/depression View Abstract
Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex and their combination View Abstract
Stimulant Effectiveness in Well Controlled Versus Poorly Controlled Pediatric Epilepsy View Abstract
Risperidone Treatment in Pediatric Patients with Epilepsy: Systematic Review of Medical Records View Abstract
Aggressive Youth on Divalproex: Effectiveness as Reviewed in Medical Records View Abstract
Risperidone Treatment in Pediatric Patients with Epilepsy: Systematic Review of Medical Records View Abstract
Stimulant Effectiveness in Well Controlled Versus Poorly Controlled Pediatric Epilepsy View Abstract
Stimulant Effectiveness in Well Controlled Versus Poorly Controlled Pediatric Epilepsy View Abstract
Sertaline Treatment for Young Children: Systematic Review of Medical Records View Abstract
Aggressive Youth on Divalproex: Effectiveness as Reviewed in Medical Records View Abstract
Future of technology to augment patient support in hospitals. View Abstract
A case series of eight aggressive young children treated with risperidone. View Abstract
Corticotropin releasing hormone increases apparent potency of adrenocorticotropic hormone stimulation of cortisol secretion. View Abstract
Risperidone Treatment in Pediatric Patients with Epilepsy: Systematic Review of Medical Records View Abstract
3 Years of a Pediatric Psychopharmacology Electronic Medical Records System View Abstract
An Open Study of Sustained Release Bupropion in Adults with ADHD and Substance Use Disorders View Abstract
Illness-related concerns of mothers of children with congenital heart disease. View Abstract
Risperidone Treatment for Aggressive Preschool Children: Systematic Review of Medical Records View Abstract
Nefazodone for Depression in Bipolar and Non-Bipolar Youth: Systematic Review of Electronic Medical Records View Abstract
Method and system for displaying icons representing informational items stored in a database View Abstract
Method and system for displaying icons representing informational items stored in a database View Abstract
Corticotropin releasing hormone increases Apparent Potency of ACTH Stimulation of Cortisol Secretion View Abstract
Zora: A Pilot Virtual Community in the Pediatric Dialysis Unit View Abstract
Cardiac Experience Journal: A computer-based intervention for families facing pediatric heart disease. Available online: http://www.experiencejournal.com View Abstract
Zora: a pilot virtual community in the pediatric dialysis unit. View Abstract
A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. View Abstract
Implementation of an electronic medical record system in a pediatric psychopharmacology program. View Abstract
The experience journal: a computer-based intervention for families facing congenital heart disease. View Abstract
Olanzapine in the Treatment of Bipolar Disorder in Juveniles View Abstract
Bupropion SR for Attention Deficit Hyperactivity Disorder (ADHD)in Adults with Bipolar Disorder (BPD)and ADHD View Abstract
Zora: A Pilot Virtual Community in the Pediatric Dialysis Unit View Abstract
Epilepsy in children and adolescents. View Abstract
Using 'off the shelf', computer programs to mine additional insights from published data: diurnal variation in potency of ACTH stimulation of cortisol secretion revealed. View Abstract
Interactive Storytelling Environments: Coping with Cardiac Illness at Boston's Children's Hospital View Abstract
Experience Journals: Using Computers to Share Stories About Illness and Medical Intervention View Abstract
Experience Journals: Using Computers to Share Stories About Illness and Medical Intervention View Abstract
Experience journals: using computers to share personal stories about illness and medical intervention. View Abstract
Computer Modeling of Human Data Reveals CRH Increases the Potency of ACTH Effect on Cortisol and Rate of Cortisol Degradation With Differences in Sexually Abused Girls View Abstract
Computer Modeling of Human Data Reveals CRH Increases the Potency of ACTH Effect on Cortisol and Rate of Cortisol Degradation With Differences in Sexually Abused Girls View Abstract
A Neural Network Approach to Modelling Personality Development View Abstract
Book Review of Child and Adolescent Depression: Clinical and Research Perspectives View Abstract
Transexuals: MCMI-II Severe Personality Disorder Incidence Depends on Setting and Sex View Abstract
A Computer Simulation of the Hypothalamic-Pituitary-Adrenal Axis View Abstract
A Computer Stimulation of the Hypothalamic-Pituitary-Adrenal Axis View Abstract
Book Review of The Kaspar Hauser Syndrome of "Psychosocial Dwarfism": Deficient Statural, Intellectual and Social Growth Induced by Child Abuse View Abstract
A computer simulation of the hypothalamic-pituitary-adrenal axis. View Abstract
Rates of Personality Disorders in Gender Dysphorics Using a Self Report Inventory, the MCMI-II View Abstract
Using neural networks to model personality development. View Abstract
Testing the psychogenic vomiting diagnosis. Four pediatric patients. View Abstract
Testing the Psychogenic Vomitting Diagnosis: Four Pediatric Patients View Abstract
Postsynaptic localization of 5-HT1D receptor binding sites in human caudate. View Abstract
Serotonin receptor and reuptake sites: pharmacologic significance. View Abstract
Aphrodiesiology: History, Folklore and Efficacy. In: The Pharmacology and Endocrinology of Sexual Function View Abstract
Reductions of Serotonergic Receptors in Alzheimer's Disease: An Autoradiographic Study View Abstract