Lauren Henderson, MD, MMSc
Rheumatologist, Rheumatology Program
Associate Professor of Pediatrics, Harvard Medical School
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Lauren Henderson, MD, MMSc
Rheumatologist, Rheumatology Program
Associate Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Graduate School
Harvard Medical School
2014
Boston
MA
Medical School
Harvard Medical School
2008
Boston
MA
Internship
Boston Children's Hospital
2009
Boston
MA
Residency
Boston Children's Hospital
2011
Boston
MA
Fellowship
Pediatric Rheumatology
Boston Children's Hospital
2015
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Rheumatology)
Publications
Macrophage Activation Syndrome: Not Just for Rheumatologists Anymore. View Abstract
Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. View Abstract
Multidisciplinary approach to treating complex immune dysregulation disorders: an adaptive model for institutional implementation. View Abstract
A progranulin variant causing childhood interstitial lung disease responsive to anti-TNF-a biologic therapy. View Abstract
T cell and autoantibody profiling for primary immune regulatory disorders. View Abstract
The 'Treg paradox' in inflammatory arthritis. View Abstract
Features of hyperinflammation link the biology of Epstein-Barr virus infection and cytokine storm syndromes. View Abstract
Hyperferritinemia Screening to Aid Identification and Differentiation of Patients with Hyperinflammatory Disorders. View Abstract
Severe Features of Systemic Juvenile Idiopathic Arthritis in Patients With Congenital Heart Disease. View Abstract
Real-world application of the pediatric Glucocorticoid Toxicity Index in childhood-onset lupus. View Abstract
Hyperferritinemia screening to aid identification and differentiation of patients with hyperinflammatory disorders. View Abstract
COVID-19-Related Multi-systemic Inflammatory Syndrome in Children (MIS-C). View Abstract
Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. View Abstract
Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. View Abstract
Outcomes of hematopoietic stem cell gene therapy for Wiskott-Aldrich syndrome. View Abstract
Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis. View Abstract
The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS). View Abstract
The 2022 EULAR/ACR points to consider at the early stages of diagnosis and management of suspected haemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). View Abstract
Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. View Abstract
Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. View Abstract
The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. View Abstract
mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. View Abstract
Dr. Degar et al reply. View Abstract
SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. View Abstract
An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. View Abstract
HLH treatment: smarter, not harder. View Abstract
Genetic diagnosis of immune dysregulation can lead to targeted therapy for interstitial lung disease: A case series and single center approach. View Abstract
Fc?R-mediated SARS-CoV-2 infection of monocytes activates inflammation. View Abstract
Ageing and interferon gamma response drive the phenotype of neutrophils in the inflamed joint. View Abstract
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 3. View Abstract
Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. View Abstract
Arthritis flares mediated by tissue-resident memory TÂ cells in the joint. View Abstract
Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. View Abstract
Coagulation profiles and viscoelastic testing in multisystem inflammatory syndrome in children. View Abstract
Clinical features of multisystem inflammatory syndrome in children. View Abstract
Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C). View Abstract
Deciphering the cytokine fingerprint of macrophage activation syndrome. View Abstract
A multidisciplinary assessment of pain in juvenile idiopathic arthritis. View Abstract
Reply. View Abstract
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation. View Abstract
Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach. View Abstract
Socioeconomic and Racial and/or Ethnic Disparities in Multisystem Inflammatory Syndrome. View Abstract
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 2. View Abstract
MIS-C: early lessons from immune profiling. View Abstract
Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. View Abstract
American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1. View Abstract
On the Alert for Cytokine Storm: Immunopathology in COVID-19. View Abstract
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. View Abstract
Posterior-onset Rasmussen's encephalitis with ipsilateral cerebellar atrophy and uveitis resistant to rituximab. View Abstract
Macrophage Activation Syndrome and Secondary Hemophagocytic Lymphohistiocytosis in Childhood Inflammatory Disorders: Diagnosis and Management. View Abstract
The immunologic features of patients with early-onset and polyautoimmunity. View Abstract
Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. View Abstract
Emergent high fatality lung disease in systemic juvenile arthritis. View Abstract
SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. View Abstract
A Bullseye for Children With Systemic Juvenile Idiopathic Arthritis. View Abstract
Pediatric CNS-isolated hemophagocytic lymphohistiocytosis. View Abstract
Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis-Associated and Idiopathic Chronic Anterior Uveitis. View Abstract
Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. View Abstract
Central nervous system-restricted familial hemophagocytic lymphohistiocytosis responds to hematopoietic cell transplantation. View Abstract
Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. View Abstract
Histopathologic Correlates of Familial Hemophagocytic Lymphohistiocytosis Isolated to the Central Nervous System. View Abstract
Patients with CD3G mutations reveal a role for human CD3? in Treg diversity and suppressive function. View Abstract
Abnormalities of T-cell receptor repertoire in CD4+ regulatory and conventional T cells in patients with RAG mutations: Implications for autoimmunity. View Abstract
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. View Abstract
Characterization of T and B cell repertoire diversity in patients with RAG deficiency. View Abstract
Frequency and Morbidity of Temporomandibular Joint Involvement in Adult Patients With a History of Juvenile Idiopathic Arthritis. View Abstract
Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis. View Abstract
Ligase-4 Deficiency Causes Distinctive Immune Abnormalities in Asymptomatic Individuals. View Abstract
Medication use in juvenile uveitis patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance Registry. View Abstract
IMMUNODEFICIENCIES. Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations. View Abstract
A70: medication use in the treatment of juvenile idiopathic uveitis patients enrolled in the childhood arthritis and rheumatology research alliance registry. View Abstract
A119: deep sequencing analysis of the T regulatory and T effector repertoire in juvenile idiopathic arthritis. View Abstract
A161: Novel 3-Dimensional Explant Method Facilitates the Study of Lymphocyte Populations in the Synovium and Reveals a Large Population of Resident Memory T cells in Rheumatoid Arthritis. View Abstract
A systematic analysis of recombination activity and genotype-phenotype correlation in human recombination-activating gene 1 deficiency. View Abstract
Dr. Henderson, et al reply. View Abstract
Expanding the spectrum of recombination-activating gene 1 deficiency: a family with early-onset autoimmunity. View Abstract
Shrinking lung syndrome as a manifestation of pleuritis: a new model based on pulmonary physiological studies. View Abstract
First reported case of Omenn syndrome in a patient with reticular dysgenesis. View Abstract