Lynda Schneider , MD

Section Chief, Allergy and Asthma Program
Professor of Pediatrics, Harvard Medical School
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Lynda Schneider, MD

Lynda Schneider , MD

Section Chief, Allergy and Asthma Program
Professor of Pediatrics, Harvard Medical School
Education
Undergraduate School
Pennsylvania State University
1979
University Park
PA
Medical School
Jefferson Medical College
1983
Philadelphia
PA
Internship
Massachusetts General Hospital
1984
Boston
MA
Residency
Massachusetts General Hospital
1987
Boston
MA
Fellowship
Boston Children's Hospital
1989
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Allergy & Immunology (General)
American Board of Allergy & Immunology (Diagnostic Laboratory Immunology)
Professional History

Lynda Schneider received her MD from Jefferson Medical College.  She completed an internship and residency at Massachusetts General Hospital and a postdoctoral fellowship at Boston Children’s Hospital.  Dr. Schneider received the 2004 AAAAI/Aventis Women in Allergy Project Grant Award.  In 2009, she served as a member of the NIH Food Allergy Clinical Guideline Expert Panel.  In 2011, she was the Chair on the Atopic Dermatitis Practice Parameter Workgroup.

Publications

Depression and anxiety in patients with atopic dermatitis: Recognizing and addressing mental health burden. View Abstract
Long-Term Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: An Open-Label Active Treatment (REALISE Study). View Abstract
Efficacy and Safety of Epicutaneous Immunotherapy in Peanut-Allergic Toddlers: Open-Label Extension to EPITOPE. View Abstract
Corrigendum to 'A systematic review and expert Delphi Consensus recommendation on the use of vaccines in patients receiving dupilumab: A position paper of the American College of Allergy, Asthma and Immunology' [Annals of Allergy, Asthma & Immunology 133/3 (2024) 286-94]. View Abstract
Systemic Therapy for Atopic Dermatitis in Children and Adolescents: A US Expert Consensus. View Abstract
Atopic Dermatitis: Updated Guidelines From the AAAAI/ACAAI Joint Task Force on Practice Parameters. View Abstract
Updated Guidelines for Atopic Dermatitis-AAAAI/ACAAI Joint Task Force. View Abstract
Atopic Dermatitis (Eczema) Guidelines 2023: Highlights. View Abstract
Dupilumab treatment reduces caregiver-reported skin pain in patients with moderate-to-severe atopic dermatitis aged 6 months to 5 years. View Abstract
The Association Between Child Food Allergy and Family Food Insecurity in a Nationally Representative US Sample. View Abstract
Evaluation of dupilumab on the disease burden in children and adolescents with atopic dermatitis: A population-based cohort study. View Abstract
Patient-Reported Outcome Measures in Chronic Spontaneous Urticaria, Angioedema, and Atopic Dermatitis. View Abstract
Comparative safety of oral Janus kinase inhibitors versus dupilumab in patients with atopic dermatitis: A population-based cohort study. View Abstract
Characterization and Incidence of Sunflower Seed Allergy in a Pediatric Allergy Clinic. View Abstract
Managing Childhood and Adolescent Atopic Dermatitis in Primary Care: A US Expert Group Consensus. View Abstract
A systematic review and expert Delphi Consensus recommendation on the use of vaccines in patients receiving dupilumab: A position paper of the American College of Allergy, Asthma and Immunology. View Abstract
Mental health interventions for atopic dermatitis: knowledge gaps, pilot programmes and future directions. View Abstract
Atopic dermatitis (eczema) guidelines: 2023 American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology Joint Task Force on Practice Parameters GRADE- and Institute of Medicine-based recommendations. View Abstract
Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitis. View Abstract
Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. View Abstract
Systemic treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. View Abstract
Global warming and implications for epithelial barrier disruption and respiratory and dermatologic allergic diseases. View Abstract
History of S. aureus Skin Infection Significantly Associates with History of Eczema Herpeticum in Patients with Atopic Dermatitis. View Abstract
Rethinking Immunological Risk: A Retrospective Cohort Study of Severe SARS-Cov-2 Infections in Individuals With Congenital Immunodeficiencies. View Abstract
Rethinking immunologic risk: a retrospective cohort study of severe SARS-CoV-2 infections in individuals with congenital immunodeficiencies. View Abstract
Phenotypic and Endotypic Determinants of Atopic Dermatitis Severity From the Atopic Dermatitis Research Network (ADRN) Registry. View Abstract
Phase 3 Trial of Epicutaneous Immunotherapy in Toddlers with Peanut Allergy. View Abstract
Values and Preferences of Patients and Caregivers Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review. View Abstract
Cancer risk with topical calcineurin inhibitors, pimecrolimus and tacrolimus, for atopic dermatitis: a systematic review and meta-analysis. View Abstract
What Parents Should Know About Atopic Dermatitis. View Abstract
Allergen immunotherapy for atopic dermatitis: Systematic review and meta-analysis of benefits and harms. View Abstract
Dupilumab in children aged 6 months to younger than 6 years with uncontrolled atopic dermatitis: a randomised, double-blind, placebo-controlled, phase 3 trial. View Abstract
Dietary Elimination for the Treatment of Atopic Dermatitis: A Systematic Review and Meta-Analysis. View Abstract
Trustworthy Patient-Centered Guidelines: Insights From Atopic Dermatitis and a Proposal for the Future. View Abstract
Author Correction: DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. View Abstract
Bleach baths for atopic dermatitis: A systematic review and meta-analysis including unpublished data, Bayesian interpretation, and GRADE. View Abstract
Safely Reducing Hospitalizations for Anaphylaxis in Children Through an Evidence-Based Guideline. View Abstract
Atopic Dermatitis and Food Allergy: Best Practices and Knowledge Gaps-A Work Group Report from the AAAAI Allergic Skin Diseases Committee and Leadership Institute Project. View Abstract
Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results. View Abstract
High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy. View Abstract
Multiethnic genome-wide and HLA association study of total serum IgE level. View Abstract
Anaphylaxis knowledge gaps and future research priorities: A consensus report. View Abstract
Polygenic prediction of atopic dermatitis improves with atopic training and filaggrin factors. View Abstract
Whole genome sequencing identifies novel genetic mutations in patients with eczema herpeticum. View Abstract
Effect of Dupilumab on Laboratory Parameters in Adolescents with Atopic Dermatitis: Results from a Randomized, Placebo-Controlled, Phase 3 Clinical Trial. View Abstract
Improving patient education for atopic dermatitis: A randomized controlled trial of a caregiver handbook. View Abstract
Severity grading system for acute allergic reactions: A multidisciplinary Delphi study. View Abstract
Food allergy and atopic dermatitis. View Abstract
Persistent, refractory, and biphasic anaphylaxis: A multidisciplinary Delphi study. View Abstract
Long-term, open-label extension study of the efficacy and safety of epicutaneous immunotherapy for peanut allergy in children: PEOPLE 3-year results. View Abstract
Nickel Allergic Contact Dermatitis: Identification, Treatment, and Prevention. View Abstract
Combining teledermatology with nonphysician members of the health care team to address access and compliance barriers in pediatric atopic dermatitis: A needs assessment. View Abstract
Replicated methylation changes associated with eczema herpeticum and allergic response. View Abstract
Effect of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Ingestion Among Children With Peanut Allergy: The PEPITES Randomized Clinical Trial. View Abstract
Identification of children with anaphylaxis at low risk of receiving acute inpatient therapies. View Abstract
Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies. View Abstract
Acquired Cold-Induced Urticaria in Pediatric Patients: A 22-Year Experience in a Tertiary Care Center (1996-2017). View Abstract
Long-Term Outcome of Peanut Oral Immunotherapy Facilitated Initially by Omalizumab. View Abstract
A twenty-two-year experience with Hymenoptera venom immunotherapy in a US pediatric tertiary care center 1996-2018. View Abstract
Oral immunotherapy with omalizumab reverses the Th2 cell-like programme of regulatory T cells and restores their function. View Abstract
Developing drugs for treatment of atopic dermatitis in children (=3 months to <18 years of age): Draft guidance for industry. View Abstract
Photocleavage-based affinity purification of biomarkers from serum: Application to multiplex allergy testing. View Abstract
Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment. View Abstract
Effect of Varying Doses of Epicutaneous Immunotherapy vs Placebo on Reaction to Peanut Protein Exposure Among Patients With Peanut Sensitivity: A Randomized Clinical Trial. View Abstract
Combining anti-IgE with oral immunotherapy. View Abstract
Reducing Hospitalization Rates for Children With Anaphylaxis. View Abstract
Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. View Abstract
Ditching the Itch with Anti-Type 2 Cytokine Therapies for Atopic Dermatitis. View Abstract
Addendum guidelines for the prevention of peanut allergy in the United States. View Abstract
A clinical trial of intradermal and intramuscular seasonal influenza vaccination in patients with atopic dermatitis. View Abstract
Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. View Abstract
Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. View Abstract
Addendum guidelines for the prevention of peanut allergy in the United States: Summary of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. View Abstract
Addendum Guidelines for the Prevention of Peanut Allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-Sponsored Expert Panel. View Abstract
Addendum guidelines for the prevention of peanut allergy in the United States: Report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. View Abstract
Temporal and Racial Differences Associated with Atopic Dermatitis Staphylococcusaureus and Encoded Virulence Factors. View Abstract
Omalizumab facilitates rapid oral desensitization for peanut allergy. View Abstract
Multidisciplinary interventions in the management of atopic dermatitis. View Abstract
Implementation of a Standardized Clinical Assessment and Management Plan (SCAMP) for Food Challenges. View Abstract
Study of the Atopic March: Development of Atopic Comorbidities. View Abstract
Chronic mucocutaneous candidiasis associated with an SH2 domain gain-of-function mutation that enhances STAT1 phosphorylation. View Abstract
Evaluating a handbook for parents of children with food allergy: a randomized clinical trial. View Abstract
Food Allergy in Infants With Atopic Dermatitis: Limitations of Food-Specific IgE Measurements. View Abstract
Targeted deep sequencing identifies rare loss-of-function variants in IFNGR1 for risk of atopic dermatitis complicated by eczema herpeticum. View Abstract
Plasma-derived C1-INH for managing hereditary angioedema in pediatric patients: A systematic review. View Abstract
Oral immunotherapy and anti-IgE antibody treatment for food allergy. View Abstract
A Review of Multidisciplinary Interventions in Atopic Dermatitis. View Abstract
Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome associated with neonatal epidermolysis bullosa acquisita. View Abstract
Ovomucoid specific immunoglobulin E as a predictor of tolerance to cooked egg. View Abstract
Oral immunotherapy induces IgG antibodies that act through Fc?RIIb to suppress IgE-mediated hypersensitivity. View Abstract
Clinical management of atopic dermatitis: practical highlights and updates from the atopic dermatitis practice parameter 2012. View Abstract
Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis. View Abstract
Eczema and sensitization to common allergens in the United States: a multiethnic, population-based study. View Abstract
A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients. View Abstract
Atopic dermatitis complicated by eczema herpeticum is associated with HLA B7 and reduced interferon-?-producing CD8+ T cells. View Abstract
Prenatal food allergen exposures and odds of childhood peanut, tree nut, or sesame seed sensitization. View Abstract
Ovomucoid is not superior to egg white testing in predicting tolerance to baked egg. View Abstract
A holistic view on dermatitis: patch testing should be considered in patients with atopic dermatitis. Reply. View Abstract
Atopic dermatitis: a practice parameter update 2012. View Abstract
Management of difficult-to-treat atopic dermatitis. View Abstract
C1-INH concentrate for treatment of acute hereditary angioedema: a pediatric cohort from the I.M.P.A.C.T. studies. View Abstract
Predicting food challenge outcomes for baked milk: role of specific IgE and skin prick testing. View Abstract
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. View Abstract
Role of specific IgE and skin-prick testing in predicting food challenge results to baked egg. View Abstract
Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis. View Abstract
Changes in antigen-specific T-cell number and function during oral desensitization in cow's milk allergy enabled with omalizumab. View Abstract
Genetic variants in interferon regulatory factor 2 (IRF2) are associated with atopic dermatitis and eczema herpeticum. View Abstract
C1 esterase inhibitor concentrate in 1085 Hereditary Angioedema attacks--final results of the I.M.P.A.C.T.2 study. View Abstract
Predictors of clinical success in a multidisciplinary model of atopic dermatitis treatment. View Abstract
Severe atopic dermatitis and transient hypogammaglobulinemia in children. View Abstract
The signal transducer and activator of transcription 6 gene (STAT6) increases the propensity of patients with atopic dermatitis toward disseminated viral skin infections. View Abstract
Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy. View Abstract
Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis. View Abstract
Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-? response. View Abstract
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel Report. View Abstract
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. View Abstract
Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-Sponsored Expert Panel report. View Abstract
Research abstracts presented at the Fall Meeting of the New England Society of Allergy, October 23-24, 2010, Woodstock, Vermont. View Abstract
Tight junction defects in patients with atopic dermatitis. View Abstract
Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. View Abstract
Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. View Abstract
Immune response to varicella vaccine in children with atopic dermatitis compared with nonatopic controls. View Abstract
Characterizing the relationship between sesame, coconut, and nut allergy in children. View Abstract
Tree nut allergy, egg allergy, and asthma in children. View Abstract
Hypersensitivity to systemic corticosteroids: an infrequent but potentially life-threatening condition. View Abstract
Prospective study of rapid relief provided by C1 esterase inhibitor in emergency treatment of acute laryngeal attacks in hereditary angioedema. View Abstract
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum. View Abstract
Safety of influenza vaccine administration in egg-allergic patients. View Abstract
Assessment of psychological distress among children and adolescents with food allergy. View Abstract
Sesame allergy: role of specific IgE and skin-prick testing in predicting food challenge results. View Abstract
Cytokine modulation of atopic dermatitis filaggrin skin expression. View Abstract
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. View Abstract
Phenotype of atopic dermatitis subjects with a history of eczema herpeticum. View Abstract
Sesame Allergy: Role of Specific IgE and Skin Prick Testing in Predicting Food Challenge Results. View Abstract
A girl with severe hand swelling and abdominal cramps. View Abstract
Evaluation of a group intervention for children with food allergy and their parents. View Abstract
Hypotension from epinephrine in a food-allergic patient with long QT syndrome. View Abstract
Critical role of kallikrein in hereditary angioedema pathogenesis: a clinical trial of ecallantide, a novel kallikrein inhibitor. View Abstract
Cytokine modulation of atopic dermatitis filaggrin skin expression. View Abstract
Reexamining the role of TACI coding variants in common variable immunodeficiency and selective IgA deficiency. View Abstract
Integrating medical and psychological health care for children with atopic dermatitis. View Abstract
Assessment of adrenal suppression in children with asthma treated with inhaled corticosteroids: use of dehydroepiandrosterone sulfate as a screening test. View Abstract
Efficacy, safety and tolerability of a new 10% liquid intravenous immune globulin [IGIV 10%] in patients with primary immunodeficiency. View Abstract
Development of a preliminary questionnaire to assess parental response to children's food allergies. View Abstract
Visceral larva migrans associated with earthworm ingestion: clinical evolution in an adolescent patient. View Abstract
TACI is mutant in common variable immunodeficiency and IgA deficiency. View Abstract
Characteristics of mycobacterial infection in patients with immunodeficiency and nuclear factor-kappaB essential modulator mutation, with or without ectodermal dysplasia. View Abstract
Clinical features and anaphylaxis in children with cold urticaria. View Abstract
The presentation and natural history of immunodeficiency caused by nuclear factor kappaB essential modulator mutation. View Abstract
Understanding pediatric inner-city asthma: an explanatory model approach. View Abstract
A patient with severe black fly (Simuliidae) hypersensitivity referred for evaluation of suspected immunodeficiency. View Abstract
Montelukast improves asthma control in asthmatic children maintained on inhaled corticosteroids. View Abstract
Effect of anti-IgE therapy in patients with peanut allergy. View Abstract
Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations. View Abstract
Giant cell myocarditis in a 12-year-old girl with common variable immunodeficiency. View Abstract
A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO). View Abstract
X-linked hyper IgM syndrome. View Abstract
Atopic diseases and upper respiratory infections. View Abstract
Atopic diseases and upper respiratory infections. View Abstract
Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial. View Abstract
Atopic disease, rhinitis and conjunctivitis, and upper respiratory infections. View Abstract
IgE-mediated allergy and desensitization to factor IX in hemophilia B. View Abstract
Long-term therapy with recombinant interferon-gamma (rIFN-gamma) for atopic dermatitis. View Abstract
Atopic disease, rhinitis and conjunctivitis, and upper respiratory infections. View Abstract
Hepatitis C virus infection associated with administration of intravenous immune globulin. A cohort study. View Abstract
Atopic disease, rhinitis and conjunctivitis, and upper respiratory infections. View Abstract
Clinical and virologic features of hepatitis C virus infection associated with intravenous immunoglobulin. View Abstract
Intravenous immunoglobulin and hepatitis C virus: the Boston episode. View Abstract
Interleukin-4 receptor expression by human B cells: functional analysis with a human interleukin-4 toxin, DAB389IL-4. View Abstract
Quality of care for preschool children with asthma: the role of social factors and practice setting. View Abstract
Treatment of steroid-dependent asthma with recombinant interferon-gamma. View Abstract
Therapy for patients with recurrent infections and low serum IgG3 levels. View Abstract
Recombinant interferon gamma therapy for atopic dermatitis. View Abstract
Lymphokine profile in bone marrow transplant recipients. View Abstract
Induction of germ-line and mature C epsilon transcripts in human B cells stimulated with rIL-4 and EBV. View Abstract
Response to a Haemophilus influenzae type b diphtheria CRM197 conjugate vaccine in children with a defect of antibody production to Haemophilus influenzae type b polysaccharide. View Abstract
Bone marrow transplantation (BMT) for the syndrome of pigmentary dilution and lymphohistiocytosis (Griscelli's syndrome). View Abstract
Regulation of immunoglobulin (Ig)E synthesis in the hyper-IgE syndrome. View Abstract