Maitreyi Mazumdar, MD, MPH
Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School; Associate Professor in Environmental Health, Harvard T.H. Chan School of Public Health
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Maitreyi Mazumdar, MD, MPH
Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School; Associate Professor in Environmental Health, Harvard T.H. Chan School of Public Health
Medical Services
Languages
Bengali
English
Education
Undergraduate School
Yale University
1991
New Haven
CT
Graduate School
MPH
Tufts University School of Medicine
1997
Boston
MA
Medical School
Tufts University School of Medicine
1997
Boston
MA
Residency
Pediatrics
New England Medical Center
2000
Boston
MA
Residency
Chief Resident
New England Medical Center
2001
Boston
MA
Residency
Child Neurology
Boston Children's Hospital
2004
Boston
MA
Fellowship
Harvard Pediatric Health Services
Research
2006
Boston
MA
Graduate School
MSc, Epidemiology
Harvard School of Public Health
2006
Boston
MA
Fellowship
Interdisciplinary Training Program in Neurotoxicology Research
Harvard School of Public Health
2008
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
American Board of Pediatrics (General)
Professional History
My current research program studies the associations between environmental arsenic exposure and neural tube defects, a particular group of birth defects that involve the developing brain and spinal cord. The study of neural tube defects provides a unique opportunity to learn about the complex interaction between environment, genes, and nutrition, and their combined effects on the developing nervous system. The long-range goals of my research program are 1) to develop novel screening strategies, appropriate for use in resource poor settings, to identify populations at high risk of neural tube defects, 2) to direct the development of more effective, mechanism-based preventive interventions for neural tube defects and 3) to test whether the biological pathways discovered linking nutrition, environmental hazards and neural tube defect risk are also involved in less severe neurodevelopmental disorders in children. Currently, this NIH-supported research takes place among infants and children in Bangladesh, a country grappling with the largest arsenic epidemic in world history.
Approach to Care
I observed that doctors often play an important role in a family’s life, often at a time that is particularly stressful for the family. I thought that as a doctor, I could use my own particular skills – my knowledge of science – to be a resource for families during difficult times.
Publications
Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study. View Abstract
Author Response to Comments. View Abstract
Parental arsenic exposure and tissue-specific DNA methylation in Bangladeshi infants with spina bifida. View Abstract
Environmental exposures influence multigenerational epigenetic transmission. View Abstract
Developmental Milestones for Children With Down Syndrome. View Abstract
Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: a cross sectional study. View Abstract
Arsenic exposure and measures of glucose tolerance in Bangladeshi adults: A cross-sectional study. View Abstract
Maternal arsenic exposure modifies associations between arsenic, folate and arsenic metabolism gene variants, and spina bifida risk: A case?control study in Bangladesh. View Abstract
Arsenic modifies the effect of folic acid in spina bifida prevention, a large hospital-based case-control study in Bangladesh. View Abstract
The Importance of Neurosurgical Intervention and Surgical Timing for Management of Pediatric Patients with Myelomeningoceles in Bangladesh. View Abstract
Genome-wide analysis of spina bifida risk variants in a case-control study from Bangladesh. View Abstract
Arsenic modifies the effect of folic acid in spina bifida prevention, a large hospital-based case-control study in Bangladesh. View Abstract
Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. View Abstract
Pregnancy pesticide exposure and child development in low- and middle-income countries: A prospective analysis of a birth cohort in rural Bangladesh and meta-analysis. View Abstract
Clinical characteristics of children with infantile epileptic spasms syndrome from a tertiary-care hospital in Dhaka, Bangladesh. View Abstract
Prepregnancy exposure to dietary arsenic and congenital heart defects. View Abstract
Identifying biomarkers for epilepsy after cerebral malaria in Zambian children: rationale and design of a prospective observational study. View Abstract
Pre-pregnancy exposure to arsenic in diet and non-cardiac birth defects. View Abstract
Response to: Correspondence on: Household use of crop residues and fuelwood for cooking and newborn birth size in rural Bangladesh by Lee et al. View Abstract
Household use of crop residues and fuelwood for cooking and newborn birth size in rural Bangladesh. View Abstract
Neural tube defects prevalence does not increase after modification of the folic acid fortification program in Chile. View Abstract
Arsenic exposure during pregnancy and postpartum maternal glucose tolerance: evidence from Bangladesh. View Abstract
Bayesian kernel machine regression-causal mediation analysis. View Abstract
A Cross-validated Ensemble Approach to Robust Hypothesis Testing of Continuous Nonlinear Interactions: Application to Nutrition-Environment Studies. View Abstract
Parental metal exposures as potential risk factors for spina bifida in Bangladesh. View Abstract
Umbilical Cord Blood Metal Mixtures and Birth Size in Bangladeshi Children. View Abstract
Feasibility of Lead Exposure Assessment in Blood Spots using Energy-Dispersive X-ray Fluorescence. View Abstract
Stunting and lead: using causal mediation analysis to better understand how environmental lead exposure affects cognitive outcomes in children. View Abstract
EEG markers predictive of epilepsy risk in pediatric cerebral malaria - A feasibility study. View Abstract
Development and Evaluation of a Pediatric Epilepsy Training Program for First Level Providers in Zambia. View Abstract
Association of prenatal pesticide exposures with adverse pregnancy outcomes and stunting in rural Bangladesh. View Abstract
A case-control analysis of maternal diet and risk of neural tube defects in Bangladesh. View Abstract
Med4way: a Stata command to investigate mediating and interactive mechanisms using the four-way effect decomposition. View Abstract
Lead in Air in Bangladesh: Exposure in a Rural Community with Elevated Blood Lead Concentrations among Young Children. View Abstract
Identification of novel loci associated with infant cognitive ability. View Abstract
Growth parameters at birth mediate the relationship between prenatal manganese exposure and cognitive test scores among a cohort of 2- to 3-year-old Bangladeshi children. View Abstract
Prenatal arsenic exposure, child marriage, and pregnancy weight gain: Associations with preterm birth in Bangladesh. View Abstract
Prenatal folic acid use associated with decreased risk of myelomeningocele: A case-control study offers further support for folic acid fortification in Bangladesh. View Abstract
Investigating causal relation between prenatal arsenic exposure and birthweight: Are smaller infants more susceptible? View Abstract
Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment. View Abstract
Anthropometric measures at birth and early childhood are associated with neurodevelopmental outcomes among Bangladeshi children aged 2-3years. View Abstract
The Joint Effect of Prenatal Exposure to Metal Mixtures on Neurodevelopmental Outcomes at 20-40 Months of Age: Evidence from Rural Bangladesh. View Abstract
Associations between post translational histone modifications, myelomeningocele risk, environmental arsenic exposure, and folate deficiency among participants in a case control study in Bangladesh. View Abstract
Does arsenic increase the risk of neural tube defects among a highly exposed population? A new case-control study in Bangladesh. View Abstract
Stunting is associated with blood lead concentration among Bangladeshi children aged 2-3 years. View Abstract
Neurodevelopmental outcomes among 2- to 3-year-old children in Bangladesh with elevated blood lead and exposure to arsenic and manganese in drinking water. View Abstract
Estimating Effects of Arsenic Exposure During Pregnancy on Perinatal Outcomes in a Bangladeshi Cohort. View Abstract
Polymorphisms in maternal folate pathway genes interact with arsenic in drinking water to influence risk of myelomeningocele. View Abstract
Arsenic is associated with reduced effect of folic acid in myelomeningocele prevention: a case control study in Bangladesh. View Abstract
Elevated sweat chloride levels due to arsenic toxicity. View Abstract
Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. View Abstract
Contaminated turmeric is a potential source of lead exposure for children in rural Bangladesh. View Abstract
Journal club: pretreatment EEG in childhood absence epilepsy. View Abstract
A prospective cohort study of the association between drinking water arsenic exposure and self-reported maternal health symptoms during pregnancy in Bangladesh. View Abstract
Prenatal lead levels, plasma amyloid ß levels, and gene expression in young adulthood. View Abstract
Low-level environmental lead exposure in childhood and adult intellectual function: a follow-up study. View Abstract
Risk of death is not increased in children with simple febrile seizures. View Abstract
Febrile seizures and risk of death. View Abstract
No association between parental or subject occupation and brain tumor risk. View Abstract
Preventing stroke among children with sickle cell anemia: an analysis of strategies that involve transcranial Doppler testing and chronic transfusion. View Abstract
Does albendazole affect seizure remission and computed tomography response in children with neurocysticercosis? A Systematic review and meta-analysis. View Abstract
X-linked creatine transporter defect: a report on two unrelated boys with a severe clinical phenotype. View Abstract
Creatine deficiency syndrome: A case of defective creatine transport presenting with episodic dystonia View Abstract
Locations