Michael Singh, MD
Director, Adult Marfan Syndrome/Connective Tissue Disorder Clinic; Inpatient Director, Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Program; Senior Associate Cardiologist
Assistant Professor of Pediatrics, Harvard Medical School
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Michael Singh, MD
Director, Adult Marfan Syndrome/Connective Tissue Disorder Clinic; Inpatient Director, Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Program; Senior Associate Cardiologist
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Columbia Union College
1992
Takoma Park
MD
Medical School
Loma Linda University
1996
Loma Linda
CA
Internship
Medical College of Ohio
1997
Toledo
OH
Residency
Medical College of Ohio
2000
Toledo
OH
Fellowship
Baystate Medical Center, Tufts University of Medicine
2003
Boston
MA
Fellowship
Boston Children's Hospital/Brigham & Women's Hospital
2004
Boston
MA
Certifications
American Board of Internal Medicine (General)
American Board of Internal Medicine (Adult Congenital Heart Disease)
American Board of Internal Medicine (Cardiovascular Disease)
American Board of Pediatrics (General)
Professional History
Dr. Singh completed his M.D. at Loma Linda University Medical Center in California; Internal Medicine/Pediatric residency at the Medical College of Ohio; Adult Cardiovascular Disease fellowship at Baystate Medical Center-Tufts University of Medicine in Massachusetts; and Marfan Syndrome/Connective Tissue Disorder and Adult Congenital Heart Disease fellowships at Boston Children's Hospital and Brigham & Women’s Hospital. In addition to being co-director of the Adult Marfan Sydrome/Related Connective Tissue Disorder and Aortic Disease program of the Cardiovascular Genetics Service, he is also the inpatient director of the Boston Adult Congenital Heart (BACH)/Pulmonary Hypertension service. He is a staff cardiologist at the Brigham & Women’s Hospital and Boston Children's Hospital. His clinical efforts have centered on supporting existing programs in congenital heart disease, pulmonary hypertension, and pregnancy in congenital heart disease, currently spanning Brigham & Women’s Hospital and Boston Children’s Hospital, as well as, the establishment of regional center of excellence for adolescents and adults with Marfan syndrome and related connective tissue disorders at both Brigham & Women’s Hospital and Boston Children's Hospital. His research interests include aortic health, and database direction and development of outcomes assessment tools.
Approach to Care
Dr. Michael Singh is originally from Takoma Park, Maryland and first came to Boston for his fellowships at Boston Children’s and Brigham and Women’s Hospital in 2003. He is acutely aware of the unique challenges patients with congenital heart disease and cardiovascular genetic conditions face as they age out of pediatric care, and has dedicated his cardiology practice to this population. Dr. Singh is committed to providing top-quality, lifelong care to his patients, who range from teenagers to adults in their golden years. Dr. Singh’s particular interests include aortopathies and aortic health in Marfan Syndrome and related connective tissue disorders, congenital heart conditions such as tetralogy of Fallot, coarctation of the aorta, single ventricle/Fontan and bicuspid aortic valve, and caring for patients with congenital heart disease and connective tissue disorder through pregnancy.
Publications
Acute Effects of Enhanced External Counterpulsation in Adults With Fontan Circulation. View Abstract
Genetic syndromes associated with congenital heart disease. View Abstract
The Impact of Pregnancy in Patients with Thoracic Aortic Disease: Epidemiology, Risk Assessment, and Management Considerations. View Abstract
Genetically Triggered Thoracic Aortic Disease: Who Should be Tested? View Abstract
Molecular characterization and investigation of the role of genetic variation in phenotypic variability and response to treatment in a large pediatric Marfan syndrome cohort. View Abstract
Effect of Losartan or Atenolol on Children and Young Adults With Bicuspid Aortic Valve and Dilated Aorta. View Abstract
Surgical management of pediatric renovascular hypertension and midaortic syndrome at a single-center multidisciplinary program. View Abstract
Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience. View Abstract
Prevalence and Prognostic Association of a Clinical Diagnosis of Depression in Adult Congenital Heart Disease: Results of the Boston Adult Congenital Heart Disease Biobank. View Abstract
Planned vaginal delivery and cardiovascular morbidity in pregnant women with heart disease. View Abstract
Creatinine versus cystatin C to estimate glomerular filtration rate in adults with congenital heart disease: Results of the Boston Adult Congenital Heart Disease Biobank. View Abstract
Early and Midterm Outcomes of Valve-Sparing Aortic Root Replacement-Reimplantation Technique. View Abstract
Transcatheter Aortic Valve Replacement for Bioprosthetic Aortic Stenosis in Pregnancy. View Abstract
Relationship of Red Cell Distribution Width to Adverse Outcomes in Adults With Congenital Heart Disease (from the Boston Adult Congenital Heart Biobank). View Abstract
Whole Exome Sequencing Reveals a Monogenic Cause of Disease in ˜43% of 35 Families With Midaortic Syndrome. View Abstract
Three-generation family with novel contiguous gene deletion on chromosome 2p22 associated with thoracic aortic aneurysm syndrome. View Abstract
Longitudinal Changes in Segmental Aortic Stiffness Determined by Cardiac Magnetic Resonance in Children and Young Adults With Connective Tissue Disorders (the Marfan, Loeys-Dietz, and Ehlers-Danlos Syndromes, and Nonspecific Connective Tissue Disorders). View Abstract
Design and Implementation of a Prospective Adult Congenital Heart Disease Biobank. View Abstract
Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients. View Abstract
Response to Letters Regarding Article "Segmental Aortic Stiffness in Children and Young Adults With Connective Tissue Disorders: Relationships With Age, Aortic Size, Rate of Dilation, and Surgical Root Replacement". View Abstract
Galectin-3 Is Elevated and Associated With Adverse Outcomes in Patients With Single-Ventricle Fontan Circulation. View Abstract
Recent Clinical Drug Trials Evidence in Marfan Syndrome and Clinical Implications. View Abstract
Segmental Aortic Stiffness in Children and Young Adults With Connective Tissue Disorders: Relationships With Age, Aortic Size, Rate of Dilation, and Surgical Root Replacement. View Abstract
Distinct effects of losartan and atenolol on vascular stiffness in Marfan syndrome. View Abstract
Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes. View Abstract
Pheochromocytoma and paraganglioma in cyanotic congenital heart disease. View Abstract
Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. View Abstract
Aortic valve dysfunction and aortic dilation in adults with coarctation of the aorta. View Abstract
MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery. View Abstract
A shifting approach to management of the thoracic aorta in bicuspid aortic valve. View Abstract
Bicuspid aortic valve and associated aortic dilation in the young. View Abstract
Increased vertebral artery tortuosity index is associated with adverse outcomes in children and young adults with connective tissue disorders. View Abstract
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. View Abstract
Care of the adult with congenital heart disease. View Abstract
Stacked proximal aortic cuffs: an "off-the-shelf" solution for treating focal thoracic aortic pathology. View Abstract
Locations