Paul Rosenberg, MD, PhD
Senior Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School
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Paul Rosenberg, MD, PhD
Senior Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School
Medical Services
Education
Medical School
Albert Einstein College of Medicine
1978
Bronx
NY
Internship
The University Hospital
1979
Boston
MA
Residency
Longwood Area Neurological Training Program
1982
Boston
MA
Fellowship
Boston Children's Hospital
1985
Boston
MA
Professional History
Dr. Rosenberg combines research with clinical practice in sleep medicine. His research has been devoted to understanding brain injury in premature infants, basic mechanisms of sleep, as well as neurodegenerative disorders.
Approach to Care
I entered medicine to use our knowledge to advance our understanding of medical and specifically neurological problems through research, to provide the basis for improved treatments of these problems, and to use medical knowledge to take care of patients with diseases and disorders of the nervous system.
Publications
Impairment of hippocampal long-term potentiation by soluble amyloid-ß oligomers is mediated by glutamate transporter 1 expressed in neurons. View Abstract
Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT-1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide production. View Abstract
Developmental regulation of zinc homeostasis in differentiating oligodendrocytes. View Abstract
Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress. View Abstract
Developmental regulation of zinc homeostasis in differentiating oligodendrocytes. View Abstract
Deletion of the Sodium-Dependent Glutamate Transporter GLT-1 in Maturing Oligodendrocytes Attenuates Myelination of Callosal Axons During a Postnatal Phase of Central Nervous System Development. View Abstract
Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus. View Abstract
Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration. View Abstract
Blood-Brain Barrier Breakdown in Relationship to Alzheimer and Vascular Disease. View Abstract
Non-Cell-Autonomous Regulation of Optic Nerve Regeneration by Amacrine Cells. View Abstract
Glutamate homeostasis and dopamine signaling: Implications for psychostimulant addiction behavior. View Abstract
The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc. View Abstract
Association of cerebrovascular reactivity and Alzheimer pathologic markers with cognitive performance. View Abstract
Cerebrovascular reactivity mapping using intermittent breath modulation. View Abstract
Conditional Knockout of GLT-1 in Neurons Leads to Alterations in Aspartate Homeostasis and Synaptic Mitochondrial Metabolism in Striatum and Hippocampus. View Abstract
Why and how to investigate the role of protein phosphorylation in ZIP and ZnT zinc transporter activity and regulation. View Abstract
STIM1-Ca2+ signaling in coronary sinus cardiomyocytes contributes to interatrial conduction. View Abstract
Divergent roles of astrocytic versus neuronal EAAT2 deficiency on cognition and overlap with aging and Alzheimer's molecular signatures. View Abstract
Zinc homeostasis and zinc signaling in white matter development and injury. View Abstract
Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. View Abstract
Ventral tegmental area astrocytes orchestrate avoidance and approach behavior. View Abstract
Deletion of Neuronal GLT-1 in Mice Reveals Its Role in Synaptic Glutamate Homeostasis and Mitochondrial Function. View Abstract
Huntington's disease pattern of transcriptional dysregulation in the absence of mutant huntingtin is produced by knockout of neuronal GLT-1. View Abstract
Behavioral phenotyping and dopamine dynamics in mice with conditional deletion of the glutamate transporter GLT-1 in neurons: resistance to the acute locomotor effects of amphetamine. View Abstract
Chromis-1, a Ratiometric Fluorescent Probe Optimized for Two-Photon Microscopy Reveals Dynamic Changes in Labile Zn(II) in Differentiating Oligodendrocytes. View Abstract
Zinc chelation and Klf9 knockdown cooperatively promote axon regeneration after optic nerve injury. View Abstract
Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration. View Abstract
An Evaluation of Situation Reports and Incident Notices: The DBPR/ESRB Experience. View Abstract
GLT-1: The elusive presynaptic glutamate transporter. View Abstract
Clinical heterogeneity associated with KCNA1 mutations include cataplexy and nonataxic presentations. View Abstract
GLT-1 Transport Stoichiometry Is Constant at Low and High Glutamate Concentrations when Chloride Is Substituted by Gluconate. View Abstract
Differential Diagnosis of a Periapical Radiolucent Lesion. A Case Report and Review of the Literature. View Abstract
Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes. View Abstract
Histological observations of pulpal replacement tissue in immature dog teeth after revascularization of infected pulps. View Abstract
Familial testicular germ cell tumors (FTGCT) - overview of a multidisciplinary etiologic study. View Abstract
Treatment of a large cystlike inflammatory periapical lesion associated with mature necrotic teeth using regenerative endodontic therapy. View Abstract
Dysregulation of system xc(-) expression induced by mutant huntingtin in a striatal neuronal cell line and in R6/2 mice. View Abstract
Changes in QTc interval in the citalopram for agitation in Alzheimer's disease (CitAD) randomized trial. View Abstract
The challenge of understanding cerebral white matter injury in the premature infant. View Abstract
Pathophysiology of glia in perinatal white matter injury. View Abstract
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. View Abstract
Ceftriaxone treatment after traumatic brain injury restores expression of the glutamate transporter, GLT-1, reduces regional gliosis, and reduces post-traumatic seizures in the rat. View Abstract
Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion. View Abstract
Decreased expression of GLT-1 in the R6/2 model of Huntington's disease does not worsen disease progression. View Abstract
Glutamate transporter expression and function in a striatal neuronal model of Huntington's disease. View Abstract
Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography. View Abstract
Expression of EAAT2 in neurons and protoplasmic astrocytes during human cortical development. View Abstract
Hyperbaric articaine with or without fentanyl in spinal anaesthesia: patient and observer blinded comparison. View Abstract
Histologic observation of a human immature permanent tooth with irreversible pulpitis after revascularization/regeneration procedure. View Abstract
STIM1-Ca(2+) signaling is required for the hypertrophic growth of skeletal muscle in mice. View Abstract
Responses of immature permanent teeth with infected necrotic pulp tissue and apical periodontitis/abscess to revascularization procedures. View Abstract
Fibroblast growth factor homologous factor 13 regulates Na+ channels and conduction velocity in murine hearts. View Abstract
Reprint of "The developing oligodendrocyte: key cellular target in brain injury in the premature infant". View Abstract
Repair and regeneration in endodontics. View Abstract
The developing oligodendrocyte: key cellular target in brain injury in the premature infant. View Abstract
Glutamate receptors, transporters, and periventricular leukomalacia View Abstract
RIP1 kinase mediates arachidonic acid-induced oxidative death of oligodendrocyte precursors. View Abstract
In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). View Abstract
Guided tissue regeneration in periapical surgery. View Abstract
Evaluation of pathologists (histopathology) and radiologists (cone beam computed tomography) differentiating radicular cysts from granulomas. View Abstract
Neuroanatomical correlates of depression in post traumatic brain injury: preliminary results of a pilot study. View Abstract
RIP1 kinase mediates
arachidonic acid-induced oxidative death of oligodendrocyte precursors View Abstract
Identify the endodontic treatment modalities. View Abstract
Evidence for change in current-flux coupling of GLT1 at high glutamate concentrations in rat primary forebrain neurons and GLT1a-expressing COS-7 cells. View Abstract
17beta-estradiol protects against hypoxic/ischemic white matter damage in the neonatal rat brain. View Abstract
Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes. View Abstract
Regulation of glutamate transport in developing rat oligodendrocytes. View Abstract
Nonsurgical root canal therapy of large cyst-like inflammatory periapical lesions and inflammatory apical cysts. View Abstract
Pulse oximetry: review of a potential aid in endodontic diagnosis. View Abstract
Evidence for change in current flux coupling of GLT1 at high glutamate concentrations in primary forebrain neurons and GLT1a expressing COS7 cells View Abstract
Regulation of glutamate transport in developing rat oligodendrocytes View Abstract
Tumor necrosis factor alpha mediates lipopolysaccharide-induced microglial toxicity to developing oligodendrocytes when astrocytes are present. View Abstract
Glutamate transporter EAAT2 expression is up-regulated in reactive astrocytes in human periventricular leukomalacia. View Abstract
Novel lipoxygenase inhibitors as neuroprotective reagents. View Abstract
Epilepsy and dental procedures. A review. View Abstract
Hyperoxia causes maturation-dependent cell death in the developing white matter. View Abstract
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. View Abstract
One-appointment endodontic therapy: biological considerations. View Abstract
Intracellular zinc release, 12-lipoxygenase activation and MAPK dependent neuronal and oligodendroglial death. View Abstract
Estradiol attenuates hyperoxia-induced cell death in the developing white matter. View Abstract
NMDA receptor-mediated extracellular adenosine accumulation is blocked by phosphatase 1/2A inhibitors. View Abstract
The glutamate transporter EAAT2 is transiently expressed in developing human cerebral white matter. View Abstract
Proliferation of epithelial cell rests, formation of apical cysts, and regression of apical cysts after periapical wound healing. View Abstract
Treatment planning: a new paradigm. View Abstract
Comparison of 4% articaine with 1:100,000 epinephrine and 2% lidocaine with 1:100,000 epinephrine when used as a supplemental anesthetic. View Abstract
Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1. View Abstract
The glutamate transporter EAAT2 is transiently expressed in developing human
cerebral white matter
View Abstract
Nitric oxide-induced adenosine inhibition of hippocampal synaptic transmission depends on adenosine kinase inhibition and is cyclic GMP independent. View Abstract
Nitric oxide production in the basal forebrain is required for recovery sleep. View Abstract
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor subunit composition and cAMP-response element-binding protein regulate oligodendrocyte excitotoxicity. View Abstract
Inducible and neuronal nitric oxide synthases (NOS) have complementary roles in recovery sleep induction. View Abstract
Oligodendrocyte excitotoxicity determined by local glutamate accumulation and mitochondrial function. View Abstract
Exercise can prevent and reverse the severity of hypertrophic cardiomyopathy. View Abstract
Intracellular zinc release and ERK phosphorylation are required upstream of 12-lipoxygenase activation in peroxynitrite toxicity to mature rat oligodendrocytes. View Abstract
Nitric oxide-induced adenosine inhibition of hippocampal synaptic transmission depends on adenosine kinase inhibition and is cGMP independent View Abstract
Inducible and neuronal nitric oxide have complementary roles in homeostatic sleep regulation View Abstract
AMPA receptor subunit composition and CREB regulate oligodendrocyte excitotoxicity View Abstract
Histological study of periradicular tissue responses to uninfected and infected devitalized pulps in dogs. View Abstract
Cellular and subcellular mRNA localization of glutamate transporter isoforms GLT1a and GLT1b in rat brain by in situ hybridization. View Abstract
Homer modulates NFAT-dependent signaling during muscle differentiation. View Abstract
Peroxynitrite generated by inducible nitric oxide synthase and NADPH oxidase mediates microglial toxicity to oligodendrocytes. View Abstract
On the role of cholinergic neurons of the basal forebrain in regulation of recovery sleep View Abstract
Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction. View Abstract
Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway. View Abstract
The major glutamate transporter of the brain, GLT1, changes its stoichiometry View Abstract
Do procedural errors cause endodontic treatment failure? View Abstract
GLT1 enters a high throughput mode at synaptic concentrations of glutamate View Abstract
Peroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation. View Abstract
Zaprinast stimulates extracellular adenosine accumulation in rat pontine slices. View Abstract
Nitric oxide-induced cell death in developing oligodendrocytes is associated with mitochondrial dysfunction and apoptosis-inducing factor translocation. View Abstract
Caspase-1 and poly (ADP-ribose) polymerase inhibitors may protect against peroxynitrite-induced neurotoxicity independent of their enzyme inhibitor activity. View Abstract
12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes. View Abstract
Developmental lag in superoxide dismutases relative to other antioxidant enzymes in premyelinated human telencephalic white matter. View Abstract
Developmental up-regulation of MnSOD in rat oligodendrocytes confers protection against oxidative injury. View Abstract
TRPC3 channels confer cellular memory of recent neuromuscular activity. View Abstract
Role of metabotropic glutamate receptors in oligodendrocyte excitotoxicity and oxidative stress. View Abstract
Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. View Abstract
Glutamate receptor-mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate. View Abstract
Elevation of intracellular cAMP evokes activity-dependent release of adenosine in cultured rat forebrain neurons. View Abstract
Effect of enamel matrix proteins on the phenotype expression of periodontal ligament cells cultured on dental materials. View Abstract
Effect of enamel matrix proteins on the periodontal connective tissue-material interface after wound healing. View Abstract
Identification of gammadeltaT lymphocytes in human periapical lesions. View Abstract
Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes. View Abstract
GLT1 is the major electrogenic glutamate transporter in cultured rat neurons View Abstract
The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons. View Abstract
Peroxynitrite induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activation View Abstract
Glutamate receptor mediated oligodendrocyte toxicity in periventricular leukomalacia: a protective role for topiramate View Abstract
The glutamate transporter GLT1a is expressed in excitatory axon terminals of mature hippocampal neurons View Abstract
Nitric oxide induces cell death through mitochondrial dysfunction and Apoptosis-Inducing Factor translocation in developing oligodendrocytes View Abstract
Zinc release and 12-lipoxygenase activation are required for peroxynitrite-induced toxicity to mature oligodendrocytes
View Abstract
Glutathione peroxidase-catalase cooperativity is required for resistance to hydrogen peroxide by mature rat oligodendrocytes View Abstract
Novel role of MGluRs in oligodendrocyte excitotoxicity and oxidative stress View Abstract
Interaction of the glutamate transporter GLT1b with the PDZ protein PICK1 and GLT1a View Abstract
Modulation of expression of the glutamate transporter GLT1/EAAT2 may be involved in the pathogenesis of PVL
View Abstract
Oligodendrocyte excitotoxicity determined by glutamate diffusion and Glur2-free AMPA receptors
View Abstract
Developmental upregulation of MnSOD in rat oligodendrocytes confers protection against oxidative toxicity View Abstract
Caspase-1 and poly (ADP-ribose) polymerase inhibitors protect against peroxynitrite-induced neurotoxicity by a direct scavenging effect View Abstract
On the role of neuronal and inducible nitric oxide synthases in regulation of sleep need
View Abstract
Elevation of intracellular cyclic AMP evokes activity dependent release of adenosine in cultured rat forebrain neurons View Abstract
Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. View Abstract
Activation of innate immunity in the CNS triggers neurodegeneration through a Toll-like receptor 4-dependent pathway. View Abstract
The role of nitric oxide in regulation of sleep need View Abstract
Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. View Abstract
Nitrosative and oxidative injury to premyelinating oligodendrocytes in periventricular leukomalacia. View Abstract
NMDA receptor-mediated extracellular adenosine accumulation in rat forebrain neurons in culture is associated with inhibition of adenosine kinase. View Abstract
Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity. View Abstract
Novel role of vitamin K in preventing oxidative injury to developing oligodendrocytes and neurons View Abstract
Transient expression of the glutamate transporter GLT1a in cerebral white matter of the developing rat brain
View Abstract
Interaction of GLT1b with the synaptic protein PICK1 View Abstract
Functional interaction of GLT1b, a variant form of the glutamate transporter GLT1, with PICK1
View Abstract
Nitric oxide: does it mediate effects of prolonged wakefulness?
View Abstract
AMPA/KA receptor mediated excitotoxicity induced by oxygen-glucose deprivation in cultured oligodendrocyte lineage cells View Abstract
Expression of inducible nitric oxide synthase and endothelial nitric oxide synthase in reactive astrocytes in human periventricular leukomalacia View Abstract
Call-tracking data and the public health response to bioterrorism-related anthrax. View Abstract
The essential nutrient pyrroloquinoline quinone may act as a neuroprotectant by suppressing peroxynitrite formation. View Abstract
The toll-like receptor TLR4 is necessary for lipopolysaccharide-induced oligodendrocyte injury in the CNS. View Abstract
Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain. View Abstract
The toll-like receptor TL4 is necessary for lipopolysaccharide-induced oligodendrocytre injury in the CNS View Abstract
The glutamate transporter GLT1b & PICK1 both localize to pre- and post-synaptic processes of pyramidal neurons as well as astrocytes of intact
adult rat View Abstract
Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain View Abstract
Expression of cGMP-specific phosphodiesterase 9A mRNA in the rat brain. View Abstract
Activation of MEF2 by muscle activity is mediated through a calcineurin-dependent pathway. View Abstract
Quantitation of catecholamines in inflamed human dental pulp by high-performance liquid chromatography. View Abstract
A variant form of the glutamate transporter GLT1 interacts with the PDZ protein PICK1 in rat forebrain View Abstract
Expression of cGMP specific phosphodiesterase 9a mRNA in the rat brain View Abstract
NBQX attenuates excitotoxic injury in developing white matter. View Abstract
NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro. View Abstract
Differential expression of glutamate receptor subtypes in human brainstem sites involved in perinatal hypoxia-ischemia. View Abstract
Nitric oxide-stimulated increase in extracellular adenosine accumulation in rat forebrain neurons in culture is associated with ATP hydrolysis and inhibition of adenosine kinase activity. View Abstract
Novel role for the NMDA receptor redox modulatory site in the pathophysiology of seizures. View Abstract
NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro View Abstract
Nitric oxide stimulated increase in extracellular adenosine accumulation in rat forebrain neurons in culture is associated with ATP hydrolysis and inhibition of adenosine kinase activity View Abstract
Novel role for the NMDA receptor redox modulatory site in the pathophysiology of seizures View Abstract
NBQX attenuates excitotoxicity in developing oligodendrocytes in vivo View Abstract
An evaluation of resin-ionomers to prevent coronal microleakage in endodontically treated teeth. View Abstract
A new Alamar Blue viability assay to rapidly quantify oligodendrocyte death. View Abstract
Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in culture. View Abstract
Axon outgrowth is regulated by an intracellular purine-sensitive mechanism in retinal ganglion cells. View Abstract
Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion. View Abstract
Dihydrokainate-sensitive neuronal glutamate transport is required for protection of rat cortical neurons in culture against synaptically released glutamate. View Abstract
The effect of occlusal reduction on pain after endodontic instrumentation. View Abstract
Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion View Abstract
Why is the role of nitric oxide in NMDA receptor function and dysfunction so controversial? View Abstract
High affinity glutamate transport in rat cortical neurons in culture. View Abstract
Why is the role of nitric oxide in NMDA receptor function and dysfunction so controversial? View Abstract
The effect of endodontic materials on periodontal ligament cell proliferation, alkaline phosphatase activity, and extracellular matrix protein synthesis in vitro. View Abstract
Characterization of brain ecto-apyrase: evidence for only one ecto-apyrase (CD39) gene. View Abstract
NMDA receptor-mediated neurotoxicity: a paradoxical requirement for extracellular Mg2+ in Na+/Ca2+-free solutions in rat cortical neurons in vitro. View Abstract
An in-vitro evaluation of sealer placement methods. View Abstract
Potential therapeutic intervention following hypoxic/ischemic insult View Abstract
NMDA receptor activation inhibits neuronal volume regulation after swelling induced by veratridine-stimulated Na+ influx in rat cortical cultures. View Abstract
Extracellular synthesis of cADP-ribose from nicotinamide-adenine dinucleotide by rat cortical astrocytes in culture. View Abstract
The glutamate transport inhibitor L-trans-pyrrolidine-2,4-dicarboxylate indirectly evokes NMDA receptor mediated neurotoxicity in rat cortical cultures. View Abstract
Cystine deprivation induces oligodendroglial death: rescue by free radical scavengers and by a diffusible glial factor. View Abstract
Forskolin evokes extracellular adenosine accumulation in rat cortical cultures. View Abstract
Comparison of fatigue for three prefabricated threaded post systems. View Abstract
NMDA receptor activation inhibits neuronal volume regulation following swelling induced by veratridine-stimulated sodium influx in rat cortical cultures View Abstract
The glutamate transport inhibitor l-trans-pyrrolidine-2,4-dicarboxylate evokes NMDA receptor mediated neurotoxicity in rat cortical cultures View Abstract
Extracellular synthesis of cyclic adenosine diphospho-ribose from NAD by rat cortical astrocytes in culture View Abstract
Controlled release of lidocaine from injectable gels and efficacy in rat sciatic nerve block. View Abstract
Vasoactive intestinal peptide regulates extracellular adenosine levels in rat cortical cultures. View Abstract
Adenylyl cyclase activation underlies intracellular cyclic AMP accumulation, cyclic AMP transport, and extracellular adenosine accumulation evoked by beta-adrenergic receptor stimulation in mixed cultures of neurons and astrocytes derived from rat cerebral cortex. View Abstract
Quantitation of catecholamines in uninflamed human dental pulp tissues by high-performance liquid chromatography. View Abstract
beta-Bungarotoxin blocks phorbol ester-stimulated phosphorylation of MARCKS, GAP-43 and synapsin I in rat brain synaptosomes. View Abstract
An in vitro evaluation of the irrigating characteristics of ultrasonic and subsonic handpieces and irrigating needles and probes. View Abstract
TOPA quinone, a kainate-like agonist and excitotoxin is generated by a catecholaminergic cell line. View Abstract
Iron-mediated oxidation of 3,4-dihydroxyphenylalanine to an excitotoxin. View Abstract
Topa quinone, a kainate-like agonist and excitotoxin, is generated by a catecholaminergic cell line View Abstract
A comparison of the apical seals achieved using retrograde amalgam fillings and the Nd:YAG laser. View Abstract
Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA. View Abstract
The putative essential nutrient pyrroloquinoline quinone is neuroprotective in a rodent model of hypoxic/ischemic brain injury. View Abstract
Beta-adrenergic receptor-mediated regulation of extracellular adenosine in cerebral cortex in culture. View Abstract
Excitatory amino acids as a final common pathway for neurologic disorders. View Abstract
Further evidence that pyrroloquinoline quinone interacts with the N-methyl-D-aspartate receptor redox site in rat cortical neurons in vitro. View Abstract
Box I and II motif from myelin basic protein gene promoter binds to nuclear proteins from rodent brain. View Abstract
Box I and II motif from myelin basic protein gene promoter binds specifically to nuclear proteins from rodent brain View Abstract
Further evidence that pyrroloquinoline quinone interacts with the NMDA receptor redox modulatory site View Abstract
Beta-adrenergic receptor mediated regulation of extracellular adenosine in cerebral cortex in culture View Abstract
The putative essential nutrient pyrroloquinoline quinone is a neuroprotectant in a rodent stroke model View Abstract
Multifactor behavioral treatment of chronic sleep-onset insomnia using stimulus control and the relaxation response. A preliminary study. View Abstract
Nonenzymatic conversion of 3,4-dihydroxyphenylalanine to 2,4,5-trihydroxyphenylalanine and 2,4,5-trihydroxyphenylalanine quinone in physiological solutions. View Abstract
Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention. View Abstract
Localization of synapses in rat cortical cultures. View Abstract
The asymmetric distribution of phosphatidylcholine in rat brain synaptic plasma membranes. View Abstract
Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention View Abstract
Localization of synapses in rat cerebral cortex in dissociated cell culture View Abstract
Non-enzymatic conversion of 3,4-dihydroxyphenylalanine (DOPA) to 2,4,5-trihydroxyphenylalanine (TOPA) and TOPA quinone in physiological solutions View Abstract
Neuronal injury evoked by depolarizing agents in rat cortical cultures. View Abstract
Inhibition of phosphorylation of synapsin I and other synaptosomal proteins by beta-bungarotoxin, a phospholipase A2 neurotoxin. View Abstract
Controlling glutamine/glutamate related neuronal injury View Abstract
Effects of snake venom phospholipase A2 toxins (beta-bungarotoxin, notexin) and enzymes (Naja naja atra, Naja nigricollis) on aminophospholipid asymmetry in rat cerebrocortical synaptosomes. View Abstract
Glutathione prevents 2,4,5-trihydroxyphenylalanine excitotoxicity by maintaining it in a reduced, non-active form. View Abstract
Method of resisting neurodegenerative disorders View Abstract
Method of resisting neurodegenerative disorders View Abstract
Functional significance of cyclic AMP secretion in cerebral cortex. View Abstract
Interaction of the putative essential nutrient pyrroloquinoline quinone with the N-methyl-D-aspartate receptor redox modulatory site. View Abstract
Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture. View Abstract
Interaction of the putative essential nutrient pyrroloquinoline quinone with the N-methyl-D-aspartate receptor redox modulatory site View Abstract
Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture View Abstract
2,4,5-trihydroxyphenylalanine in solution forms a non-N-methyl-D-aspartate glutamatergic agonist and neurotoxin. View Abstract
Accumulation of extracellular glutamate and neuronal death in astrocyte-poor cortical cultures exposed to glutamine. View Abstract
2,4,5-Trihydroxyphenylalanine in solution forms a non-NMDA glutamatergic agonist and neurotoxin View Abstract
Inhibitory effect of EDTA.Ca2+ on the hydrolysis of synaptosomal phospholipids by phospholipase A2 toxins and enzymes. View Abstract
A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons. View Abstract
A dopa oxidation product is a non-NMDA glutamatergic agonist View Abstract
Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. View Abstract
Extracellular cAMP accumulation and degradation in rat cerebral cortex in dissociated cell culture. View Abstract
Extracellular cAMP accumulation and degradation in rat cerebral cortex in dissociated cell culture View Abstract
Catecholamine toxicity in cerebral cortex in dissociated cell culture. View Abstract
Cell and fiber-type distribution of dystrophin. View Abstract
Catecholamine toxicity in cerebral cortex View Abstract
A small subset of cortical astrocytes in culture accumulates glycogen View Abstract
A small subset of cortical astrocytes in culture accumulates glycogen. View Abstract
Effects of norepinephrine on rat neocortical neurons in dissociated cell culture. View Abstract
Glycogen accumulation in rat cerebral cortex in dissociated cell culture. View Abstract
Local anesthetic complications: a review and case report. View Abstract
Glycogen cytochemistry in cerebral cortex in dissociated cell culture View Abstract
Afferent connections of the perirhinal cortex in the rat. View Abstract
Phospholipid distribution and stimulation of methylation during denervation and reinnervation in skeletal muscle. View Abstract
Occlusion, the dental pulp, and endodontic treatment. View Abstract
Comparison of endodontic measurement controls using a paralleling technique with a grid and a conventional measurement. View Abstract
Differential phospholipid hydrolysis by phospholipase C in sarcolemma of muscles with calcium or sodium generated action potentials. View Abstract
A quantitative examination of immunoglobulins in bovine gingiva and dental pulp. View Abstract
The effects of etching enamel with acid on human dental pulp. A preliminary study. View Abstract
The gramicidin channel: water permeability and ion-water coupling View Abstract
Single file transport: Implications for ion and water movement through gramicidin A channels View Abstract
Histologic identification of mast cells in human dental pulp. View Abstract
Interaction of ions and water in gramicidin A channels: streaming potentials across lipid bilayer membranes. View Abstract
Water permeability of gramicidin A-treated lipid bilayer membranes. View Abstract
Interaction of ions and water in gramicidin A channels. Streaming potentials across lipid bilayer membranes View Abstract
Determination of the accuracy of the Sono-Explorer for establishing endodontic measurement control. View Abstract
The effect of phospholipases and proteases on the binding of gamma-aminobutyric acid to junctional complexes of rat cerebellum. View Abstract
Role of the anesthetic solution in intrapulpal anesthesia. View Abstract
Periapical repair: apparent or real? View Abstract
The endodontic aspect of complete root amputation. View Abstract
Periapical surgery on a two-rooted maxillary central incisor. View Abstract
Exteroceptive stimulation of maternal behavior in the naive rat. View Abstract
Gold posts. Common problems in preparation and technique for fabrication. View Abstract
Lipid changes in tri-o-cresylphosphate-induced neuropathy. View Abstract
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