Sarah de Ferranti, MD, MPH
Chief, Division of Ambulatory Cardiology; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Pediatrics, Harvard Medical School
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Sarah de Ferranti, MD, MPH
Chief, Division of Ambulatory Cardiology; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
University of Michigan
1991
Ann Arbor
MI
Graduate School
MPH
Tufts University
1995
Boston
MA
Medical School
Tufts University School of Medicine
1995
Boston
MA
Residency
Boston Children's Hospital
1999
Boston
MA
Fellowship
Boston Children's Hospital
2003
Boston
MA
Media
Caregiver Profile
Meet Dr. Sarah de Ferranti
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Cardiology)
Publications
Unplanned Readmissions in Pediatric Cardiac Disease: Impacts of Social Determinants of Health. View Abstract
Myocardial Infarction in Kawasaki Disease. View Abstract
Trajectory of Cardiovascular Health Across Childhood and Adolescence. View Abstract
Implementation strategies for improving the care of familial hypercholesterolaemia from the International Atherosclerosis Society: next steps in implementation science and practice. View Abstract
Prenatal and Perinatal Factors of Life's Essential 8 Cardiovascular Health Trajectories. View Abstract
Recent updates on the screening, diagnosis, and management of lipids disorders in children and adolescents. View Abstract
Expert-Level Automated Diagnosis of the Pediatric ECG Using a Deep Neural Network. View Abstract
Correction: Isometric Exercise Does Not Affect the Diameter of the Ascending Aorta in Youth with Bicuspid Aortic Valves. View Abstract
Parent and Primary Care Clinician Perceptions About Pediatric Hypertension. View Abstract
Low-Density Lipoprotein Cholesterol Level Distributions Across Different Ages: Implications for Screening Children for Severe and Familial Hypercholesterolemia. View Abstract
Trends in Gaps of Care for Patients With Congenital Heart Disease: Implications for Social Determinants of Health and Child Opportunity Index. View Abstract
Society for Cardiovascular Magnetic Resonance 2023 Cases of SCMR case series. View Abstract
Forecasting the Burden of Cardiovascular Disease and Stroke in the United States Through 2050-Prevalence of Risk Factors and Disease: A Presidential Advisory From the American Heart Association. View Abstract
Enhanced Safety and Efficiency of Ambulatory Cardiology Admissions: A Quality Improvement Initiative. View Abstract
Implementation of the International Consortium of Health Outcomes Measurement CHD standard set in patients undergoing pulmonary valve replacement. View Abstract
It is Time to Screen for Homozygous Familial Hypercholesterolemia in the United States. View Abstract
Food Insecurity and Ideal Cardiovascular Health Risk Factors Among US Adolescents. View Abstract
Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolaemia: An expert consensus statement from ERKNet and ESPN. View Abstract
Familial Hypercholesterolemia Variant and Cardiovascular Risk in Individuals With Elevated Cholesterol. View Abstract
Social Determinants of Health Including Child Opportunity Index Leading to Gaps in Care for Patients With Significant Congenital Heart Disease. View Abstract
Genetic testing for familial hypercholesterolemia. View Abstract
Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. View Abstract
Clinical practice recommendations on lipoprotein apheresis for children with homozygous familial hypercholesterolemia: an expert consensus statement from ERKNet and ESPN. View Abstract
Still "on the Fence" About Universal Childhood Lipid Screening: The USPSTF Reaffirms an I Statement. View Abstract
International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia. View Abstract
Association of Severe Hypercholesterolemia and Familial Hypercholesterolemia Genotype With Risk of Coronary Heart Disease. View Abstract
Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry. View Abstract
MIS-C across three SARS-CoV-2 variants: Changes in COVID-19 testing and clinical characteristics in a cohort of U.S. children. View Abstract
Relationship of Left Ventricular Mass to Lean Body Mass in the Obese Pediatric Population. View Abstract
The association of objectively measured sedentary time with asthma in US youth: A glimpse into the connection between obesity and asthma. View Abstract
Using Adult Ambulatory Blood Pressure Thresholds in Youth: Impact of Nocturnal Hypertension. View Abstract
Adherence to lipid-lowering therapy and reaching treatment goals in youth seen in a preventive cardiology clinic. View Abstract
Cardiovascular Risk Assessment and Management for Pediatricians. View Abstract
Clinical response to lifestyle counseling for dyslipidemia and elevated blood pressure in childhood cancer survivors. View Abstract
Atherosclerotic Cardiovascular Risk as an Emerging Priority in Pediatrics. View Abstract
Multi-disciplinary collaborative consensus guidance statement on the assessment and treatment of postacute sequelae of SARS-CoV-2 infection (PASC) in children and adolescents. View Abstract
Prevalence of High Blood Pressure Among Youth in India and Association With Future Cardiovascular Disease. View Abstract
Lack of Age-Appropriate Reference Intervals Causing Potentially Missed Alerts in Clinical Reports of Dyslipidemia. View Abstract
Dyslipidemia Among Adults With Congenital Heart Disease. View Abstract
Isometric Exercise Increases the Diameter of the Ascending Aorta in Youth with Bicuspid Aortic Valves. View Abstract
Disproportionate Negative Career Impact of the COVID-19 Pandemic on Female Pediatric Cardiologists in the Northeast United States. View Abstract
Estimated Yield of Screening for Heterozygous Familial Hypercholesterolemia With and Without Genetic Testing in US Adults. View Abstract
Follow-up cardiac magnetic resonance in children with vaccine-associated myocarditis. View Abstract
SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association. View Abstract
Insulin Prevents Hypercholesterolemia by Suppressing 12a-Hydroxylated Bile Acids. View Abstract
Age, Sex, Race/Ethnicity, and Income Patterns in Ideal Cardiovascular Health Among Adolescents and Adults in the U.S. View Abstract
Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events. View Abstract
Activity During the COVID-19 Pandemic in Children with Cardiac Rhythm Management Devices. View Abstract
Association of Myocarditis With BNT162b2 Messenger RNA COVID-19 Vaccine in a Case Series of Children. View Abstract
Special Considerations for Healthy Lifestyle Promotion Across the Life Span in Clinical Settings: A Science Advisory From the American Heart Association. View Abstract
Low-Density Lipoprotein Cholesterol Trajectories and Prevalence of High Low-Density Lipoprotein Cholesterol Consistent With Heterozygous Familial Hypercholesterolemia in US Children. View Abstract
Perspectives on Identifying and Treating Familial Hypercholesterolemia in Childhood. View Abstract
Helping young women go red: Harnessing the power of personal and digital information to prevent heart disease. View Abstract
Detailed Assessment of Left Ventricular Function in Multisystem Inflammatory Syndrome in Children, Using Strain Analysis. View Abstract
Socioeconomic and Racial and/or Ethnic Disparities in Multisystem Inflammatory Syndrome. View Abstract
Improving Cardiovascular Health in a Pediatric Preventive Cardiology Practice. View Abstract
Multiple Emergency Department Visits for a Diagnosis of Kawasaki Disease: An Examination of Risk Factors and Outcomes. View Abstract
Variation in the management of Kawasaki disease in Australia and New Zealand: A survey of paediatricians. View Abstract
Cardiovascular health decline in adolescent girls in the NGHS cohort, 1987-1997. View Abstract
Review of Cardiac Involvement in Multisystem Inflammatory Syndrome in Children. View Abstract
Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. View Abstract
Evolocumab in Children with Heterozygous Familial Hypercholesterolemia. View Abstract
Evidence-Based Policy Making for Public Health Interventions in Cardiovascular Diseases: Formally Assessing the Feasibility of Clinical Trials. View Abstract
Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the Cascade Screening for Awareness and Detection-FH Registry. View Abstract
Primary adjunctive corticosteroid therapy is associated with improved outcomes for patients with Kawasaki disease with coronary artery aneurysms at diagnosis. View Abstract
Markers of cholesterol synthesis are elevated in adolescents and young adults with type 2 diabetes. View Abstract
Atrioventricular Block in Children With Multisystem Inflammatory Syndrome. View Abstract
Update on Preventive Cardiology. View Abstract
Medium-Term Complications Associated With Coronary Artery Aneurysms After Kawasaki Disease: A Study From the International Kawasaki Disease Registry. View Abstract
Young Women's Perceptions of Heart Disease Risk. View Abstract
Low-Molecular-Weight Heparin vs Warfarin for Thromboprophylaxis in Children With Coronary Artery Aneurysms After Kawasaki Disease: A Pragmatic Registry Trial. View Abstract
Cardiovascular Risk and Cardiovascular Health Behaviours in the Transition From Childhood to Adulthood. View Abstract
Pediatric Lipid Screening and Treatment in Canada: Practices, Attitudes, and Barriers. View Abstract
Missed or delayed diagnosis of Kawasaki disease during the 2019 novel coronavirus disease (COVID-19) pandemic. View Abstract
Practice of lipoprotein apheresis and short-term efficacy in children with homozygous familial hypercholesterolemia: Data from an international registry. View Abstract
Reducing the Clinical and Public Health Burden of Familial Hypercholesterolemia: A Global Call to Action. View Abstract
The American Heart Association 2030 Impact Goal: A Presidential Advisory From the American Heart Association. View Abstract
Anti-thrombosis management of patients with Kawasaki disease: Results from an international survey. View Abstract
The Use of Nonnutritive Sweeteners in Children. View Abstract
Type 1 diabetes is associated with an increase in cholesterol absorption markers but a decrease in cholesterol synthesis markers in a young adult population. View Abstract
Omega-3 Fatty Acids for the Management of Hypertriglyceridemia: A Science Advisory From the American Heart Association. View Abstract
Wearable Biosensors in Pediatric Cardiovascular Disease. View Abstract
Associations of Blood Pressure and Cholesterol Levels During Young Adulthood With Later Cardiovascular Events. View Abstract
The relationship between payer type and lipid outcomes in response to clinical lifestyle interventions in youth with dyslipidemia. View Abstract
Is Echocardiography Critical in Patients With Kawasaki Disease With a Z-Score < 2 6 Weeks From Onset?-Reply. View Abstract
Impact of Socioeconomic Status on Outcomes of Patients with Kawasaki Disease. View Abstract
Variation in the management of Kawasaki disease. View Abstract
Risk Model Development and Validation for Prediction of Coronary Artery Aneurysms in Kawasaki Disease in a North American Population. View Abstract
Familial Hypercholesterolemia Among Young Adults With Myocardial Infarction. View Abstract
Trends in Levels of Lipids and Apolipoprotein B in US Youths Aged 6 to 19 Years, 1999-2016. View Abstract
Fish, Shellfish, and Children's Health: An Assessment of Benefits, Risks, and Sustainability. View Abstract
Treatment Intensification in Patients With Kawasaki Disease and Coronary Aneurysm at Diagnosis. View Abstract
Impact of Treatment Modality on Vascular Function in Coarctation of the Aorta: The LOVE - COARCT Study. View Abstract
Cardiovascular Risk Reduction in High-Risk Pediatric Patients: A Scientific Statement From the American Heart Association. View Abstract
Will Teens Go Red? Low Cardiovascular Disease Awareness Among Young Women. View Abstract
Hepatotoxicity of Statins as Determined by Serum Alanine Aminotransferase in a Pediatric Cohort With Dyslipidemia. View Abstract
Association of Initially Normal Coronary Arteries With Normal Findings on Follow-up Echocardiography in Patients With Kawasaki Disease. View Abstract
Association of Maternal Prepregnancy Weight with Offspring Adiposity Throughout Adulthood over 37 Years of Follow-up. View Abstract
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
Experience participating in the American College of Cardiology Quality NetworkTM: paediatric and adult congenital cardiology collaborative quality improvement. View Abstract
Rationale and design of Long-term Outcomes and Vascular Evaluation after Successful Coarctation of the Aorta Treatment study. View Abstract
Diagnosis, Evaluation, and Management of High Blood Pressure in Children and Adolescents. View Abstract
Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel. View Abstract
Hypertriglyceridemia in Diabetes Mellitus: Implications for Pediatric Care. View Abstract
Squaring the Curve of Cardiovascular Health From the Beginning of Life. View Abstract
Prevalence and Predictors of Cholesterol Screening, Awareness, and Statin Treatment Among US Adults With Familial Hypercholesterolemia or Other Forms of Severe Dyslipidemia (1999-2014). View Abstract
Obesity, Hypertension, and Dyslipidemia in Childhood Are Key Modifiable Antecedents of Adult Cardiovascular Disease: A Call to Action. View Abstract
Awareness of Cardiovascular Risk Factors in U.S. Young Adults Aged 18-39 Years. View Abstract
Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. View Abstract
Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents. View Abstract
USPSTF is unable to recommend for or against lipid screening to identify multifactorial dyslipidaemia in childhood: no recommendation is not without consequences. View Abstract
PCSK9 Is Increased in Youth With Type 1 Diabetes. View Abstract
Safety and Efficacy of Warfarin Therapy in Kawasaki Disease. View Abstract
Statin-Associated Myopathy in a Pediatric Preventive Cardiology Practice. View Abstract
Kawasaki disease and immunisation: A systematic review. View Abstract
Cholesterol Screening and Treatment Practices and Preferences: A Survey of United States Pediatricians. View Abstract
Extracellular RNAs Are Associated With Insulin Resistance and Metabolic Phenotypes. View Abstract
Ideal Cardiovascular Health, Cardiovascular Remodeling, and Heart Failure in Blacks: The Jackson Heart Study. View Abstract
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association. View Abstract
Obesity and type 2 diabetes are associated with elevated PCSK9 levels in young women. View Abstract
Calorically restricted diets decrease PCSK9 in overweight adolescents. View Abstract
Stakeholders' Perspectives on Stakeholder-engaged Research (SER): Strategies to Operationalize Patient-centered Outcomes Research Principles for SER. View Abstract
Kawasaki disease and immunisation: Standardised case definition & guidelines for data collection, analysis. View Abstract
Transitioning from pediatric to adult health care with familial hypercholesterolemia: Listening to young adult and parent voices. View Abstract
Adolescent Dyslipidemia and Standardized Lifestyle Modification: Benchmarking Real-World Practice. View Abstract
Nutrition in Children and Adolescents. View Abstract
Response by de Ferranti et al to Letter Regarding Article, "Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES)". View Abstract
Transitions in Metabolic Risk and Long-Term Cardiovascular Health: Coronary Artery Risk Development in Young Adults (CARDIA) Study. View Abstract
Cardiovascular Consequences of Childhood Secondhand Tobacco Smoke Exposure: Prevailing Evidence, Burden, and Racial and Socioeconomic Disparities: A Scientific Statement From the American Heart Association. View Abstract
Correlates of Achieving Statin Therapy Goals in Children and Adolescents with Dyslipidemia. View Abstract
Lipid Screening in Children and Adolescents. View Abstract
Young adult and parent stakeholder perspectives on participation in patient-centered comparative effectiveness research. View Abstract
Census tract based income level and lipid levels in urban pediatric primary care: a retrospective study. View Abstract
Long-Term Risk of Atherosclerotic Cardiovascular Disease in US Adults With the Familial Hypercholesterolemia Phenotype. View Abstract
The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia. View Abstract
Adolescent Perceptions of Cholesterol Screening Results: "Young Invincibles" or Developing Adults? View Abstract
Prevalence of Familial Hypercholesterolemia in the 1999 to 2012 United States National Health and Nutrition Examination Surveys (NHANES). View Abstract
Effect of Leptin Replacement on PCSK9 in ob/ob Mice and Female Lipodystrophic Patients. View Abstract
Executive Summary: Heart Disease and Stroke Statistics--2016 Update: A Report From the American Heart Association. View Abstract
Premature subclinical atherosclerosis in children and young adults with juvenile idiopathic arthritis. A review considering preventive measures. View Abstract
Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. View Abstract
Massachusetts Pediatricians' Views Toward Body Mass Index Screening in Schools: Continued Controversy. View Abstract
The Agenda for Familial Hypercholesterolemia: A Scientific Statement From the American Heart Association. View Abstract
Effect on Physical Activity of a Randomized Afterschool Intervention for Inner City Children in 3rd to 5th Grade. View Abstract
Factors Associated with Clinical Research Recruitment in a Pediatric Academic Medical Center--A Web-Based Survey. View Abstract
Coronary Artery Aneurysm Measurement and Z Score Variability in Kawasaki Disease. View Abstract
Providing food to treat adolescents at risk for cardiovascular disease. View Abstract
Application of Pediatric and Adult Guidelines for Treatment of Lipid Levels Among US Adolescents Transitioning to Young Adulthood. View Abstract
Treatment decision making for adolescents with familial hypercholesterolemia: Role of family history and past experiences. View Abstract
Familial hypercholesterolemia in children and adolescents: A clinical perspective. View Abstract
Childhood environmental tobacco smoke exposure: a smoking gun for atherosclerosis in adulthood. View Abstract
Associations of total and abdominal adiposity with risk marker patterns in children at high-risk for cardiovascular disease. View Abstract
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. View Abstract
Rates of cholesterol screening of youth--reply. View Abstract
Cardiovascular disease risk factors in youth with diabetes mellitus: a scientific statement from the American Heart Association. View Abstract
Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association. View Abstract
Type 1 diabetes mellitus and cardiovascular disease: a scientific statement from the American Heart Association and American Diabetes Association. View Abstract
Temporal trends in pulse pressure and mean arterial pressure during the rise of pediatric obesity in US children. View Abstract
Cholesterol testing among children and adolescents during health visits. View Abstract
Using high-dose omega-3 fatty acid supplements to lower triglyceride levels in 10- to 19-year-olds. View Abstract
A compound heterozygous mutation in GPD1 causes hepatomegaly, steatohepatitis, and hypertriglyceridemia. View Abstract
Observational studies may be more important than randomized clinical trials: weaknesses in US Preventive Services Task Force recommendation on blood pressure screening in youth. View Abstract
Leveraging electronic health records to notify pediatric patients of a drug recall. View Abstract
Childhood obesity: today and tomorrow's health challenge. View Abstract
Myocardial tissue remodeling in adolescent obesity. View Abstract
Vascular health in Kawasaki disease. View Abstract
Promotion of physical activity for children and adults with congenital heart disease: a scientific statement from the American Heart Association. View Abstract
The Changing Demographics of Congenital Heart Disease Hospitalizations in the United States, 1998 Through 2010. View Abstract
NHLBI integrated pediatric guidelines: battle for a future free of cardiovascular disease. View Abstract
Pediatric metabolic syndrome: from prevention to treatment. View Abstract
Hypertension in children and adolescents: more questions than answers. View Abstract
Declining cholesterol levels in US youths: a reason for optimism. View Abstract
NHLBI Integrated Guidelines on Cardiovascular Disease Risk Reduction: can we clarify the controversy about cholesterol screening and treatment in childhood? View Abstract
Dynamic evolution of practice guidelines: analysis of deviations from assessment and management plans. View Abstract
Childhood cholesterol disorders: the iceberg base or nondisease? View Abstract
Nontraditional risk factors and biomarkers for cardiovascular disease: mechanistic, research, and clinical considerations for youth: a scientific statement from the American Heart Association. View Abstract
Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. View Abstract
Pediatric aspects of familial hypercholesterolemias: recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. View Abstract
Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. View Abstract
Hypertriglyceridemia in a pediatric referral practice: experience with 300 patients. View Abstract
Cardiovascular risk assessment and cholesterol management in adolescents: getting to the heart of the matter. View Abstract
Recovery from metabolic syndrome is both possible and beneficial. View Abstract
Endothelial pulse amplitude testing: feasibility and reproducibility in adolescents. View Abstract
Storm over statins--the controversy surrounding pharmacologic treatment of children. View Abstract
The perfect storm: obesity, adipocyte dysfunction, and metabolic consequences. View Abstract
Epidemiology of paediatric metabolic syndrome and type 2 diabetes mellitus. View Abstract
Obesity is a common comorbidity in children with congenital and acquired heart disease. View Abstract
Nonfasting low-density lipoprotein testing: utility for cholesterol screening in pediatric primary care. View Abstract
C-reactive protein: a nontraditional serum marker of cardiovascular risk. View Abstract
Inflammation and changes in metabolic syndrome abnormalities in US adolescents: findings from the 1988-1994 and 1999-2000 National Health and Nutrition Examination Surveys. View Abstract
Prevalence of the metabolic syndrome in American adolescents: findings from the Third National Health and Nutrition Examination Survey. View Abstract
Intraoperative hyperglycemia during infant cardiac surgery is not associated with adverse neurodevelopmental outcomes at 1, 4, and 8 years. View Abstract
C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. View Abstract
Direct measurement of LDL-C in children: performance of two surfactant-based methods in a general pediatric population. View Abstract
Are amoxycillin and folate inhibitors as effective as other antibiotics for acute sinusitis? A meta-analysis. View Abstract
Large trials vs meta-analysis of smaller trials: how do their results compare? View Abstract