Adrienne Randolph, MD, MSc
Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School
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Adrienne Randolph, MD, MSc
Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School
Medical Services
Languages
English
Education
Graduate School
Medical Informatics
University of Utah
Salt Lake City
UT
Graduate School
Psychology
California State University
Fresno
CA
Medical School
Stanford University School of Medicine
Stanford
CA
Internship
Children's Hospital of Philadelphia
Philadelphia
PA
Residency
University of California Medical Center
San Francisco
CA
Fellowship
Pediatric Critical Care Medicine
University of California at San Francisco and Children's Hospital
Oakland
CA
Fellowship
Health Outcomes and Health Policy Research
University of California at San Francisco
San Francisco
CA
Fellowship
Cardiovascular Medicine
University of California at San Francisco
San Francisco
CA
Fellowship
University of Utah
Salt Lake City
UT
Fellowship
University of Toronto
Toronto
Ontario
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Critical Care Medicine)
Professional History
Dr. Randolph serves as an expert for the Department of Medicine for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.
Publications
Use of procalcitonin in therapeutic decisions in the pediatric intensive care unit. View Abstract
Concordance between parent-reported and documented COVID-19 vaccination status among hospitalized children and adolescents: Implications for vaccine effectiveness estimates, May 2021-October 2023. View Abstract
The 2024 Phoenix Sepsis Score Criteria: Part 1, the Evolution in Definition of Sepsis and Septic Shock. View Abstract
The 2024 Phoenix Sepsis Score Criteria: Part 3, What About Using Stages of Sepsis in the Criteria? View Abstract
The 2024 Phoenix Sepsis Score Criteria: Part 5, What About "Parsimony" in the Criteria-Is Less Really More? View Abstract
Assessing Clinical Improvement of Infants Hospitalized for Respiratory Syncytial Virus-Related Critical Illness. View Abstract
Hospital-wide access to genomic data advanced pediatric rare disease research and clinical outcomes. View Abstract
Impact of Viral Lower Respiratory Tract Infection (LRTI) in Early Childhood (0-2 Years) on Lung Growth and Development and Lifelong Trajectories of Pulmonary Health: A National Institutes of Health (NIH) Workshop Summary. View Abstract
Consequences beyond acute SARS-CoV-2 infection in children. View Abstract
Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis. View Abstract
Pre-existing Immunocompromising Conditions and Outcomes of Acute COVID-19 Patients Admitted for Pediatric Intensive Care. View Abstract
High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases. View Abstract
Molecular mimicry in multisystem inflammatory syndrome in children. View Abstract
From ICU Syndromes to ICU Subphenotypes: Consensus Report and Recommendations for Developing Precision Medicine in the ICU. View Abstract
Enhancing sepsis biomarker development: key considerations from public and private perspectives. View Abstract
Durability of Original Monovalent mRNA Vaccine Effectiveness Against COVID-19 Omicron-Associated Hospitalization in Children and Adolescents - United States, 2021-2023. View Abstract
Adolescents and Young Adults: An Understudied, yet Likely Informative, Population in ARDS. View Abstract
International Consensus Criteria for Pediatric Sepsis and Septic Shock. View Abstract
Development and Validation of the Phoenix Criteria for Pediatric Sepsis and Septic Shock. View Abstract
The RECOVERY trial of PIMS-TS: important lessons from the pandemic. View Abstract
Characteristics and Clinical Outcomes of Vaccine-Eligible US Children Under-5 Years Hospitalized for Acute COVID-19 in a National Network. View Abstract
Neutralization of SARS-CoV-2 Omicron BQ.1, BQ.1.1 and XBB.1 variants following SARS-CoV-2 infection or vaccination in children. View Abstract
Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. View Abstract
Risk factors for health impairments in children after hospitalization for acute COVID-19 or MIS-C. View Abstract
Effectiveness of Maternal mRNA COVID-19 Vaccination During Pregnancy Against COVID-19-Associated Hospitalizations in Infants Aged <6 Months During SARS-CoV-2 Omicron Predominance - 20 States, March 9, 2022-May 31, 2023. View Abstract
The Modified Clinical Progression Scale for Pediatric Patients: Evaluation as a Severity Metric and Outcome Measure in Severe Acute Viral Respiratory Illness. View Abstract
Infants Admitted to US Intensive Care Units for RSV Infection During the 2022 Seasonal Peak. View Abstract
Transcriptomic profiles of multiple organ dysfunction syndrome phenotypes in pediatric critical influenza. View Abstract
Early, Persistent Lymphopenia Is Associated With Prolonged Multiple Organ Failure and Mortality in Septic Children. View Abstract
Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. View Abstract
Immunomodulatory Therapy for MIS-C. View Abstract
Single cell transcriptomics identifies distinct profiles in pediatric acute respiratory distress syndrome. View Abstract
Longitudinal Analysis of Contrasts in Gene Expression Data. View Abstract
Variation in Early Anakinra Use and Short-Term Outcomes in Multisystem Inflammatory Syndrome in Children. View Abstract
Operationalizing Appropriate Sepsis Definitions in Children Worldwide: Considerations for the Pediatric Sepsis Definition Taskforce. View Abstract
Extracorporeal Membrane Oxygenation Characteristics and Outcomes in Children and Adolescents With COVID-19 or Multisystem Inflammatory Syndrome Admitted to U.S. ICUs. View Abstract
Risk Factors for Multisystem Inflammatory Syndrome in Children: A Case-control Investigation. View Abstract
Community-Onset Bacterial Coinfection in Children Critically Ill With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. View Abstract
Clinical Course Associated with Aseptic Meningitis Induced by Intravenous Immunoglobulin for the Treatment of Multisystem Inflammatory Syndrome in Children. View Abstract
Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19. View Abstract
BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5-18 Years-United States, July 2021 - April 2022. View Abstract
Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children. View Abstract
Executive Summary of the Second International Guidelines for the Diagnosis and Management of Pediatric Acute Respiratory Distress Syndrome (PALICC-2). View Abstract
Pulmonary Specific Ancillary Treatment for Pediatric Acute Respiratory Distress Syndrome: From the Second Pediatric Acute Lung Injury Consensus Conference. View Abstract
Genetic Predisposition to Neurological Complications in Patients with COVID-19. View Abstract
ATP breakdown in plasma of children limits the antimicrobial effectiveness of their neutrophils. View Abstract
Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis. View Abstract
The Notch1/CD22 signaling axis disrupts Treg function in SARS-CoV-2-associated multisystem inflammatory syndrome in children. View Abstract
Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. View Abstract
Unsupervised outlier detection applied to SARS-CoV-2 nucleotide sequences can identify sequences of common variants and other variants of interest. View Abstract
Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy. View Abstract
NFKB2 haploinsufficiency identified via screening for IFN-a2 autoantibodies in children and adolescents hospitalized with SARS-CoV-2-related complications. View Abstract
DDX58 Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents. View Abstract
Association of Asthma With Treatments and Outcomes in Children With Critical Influenza. View Abstract
Pediatric Acute Lung Injury and Sepsis Investigators (PALISI): Evolution of an Investigator-Initiated Research Network. View Abstract
Postdischarge Glucocorticoid Use and Clinical Outcomes of Multisystem Inflammatory Syndrome in Children. View Abstract
Tachyarrhythmias During Hospitalization for COVID-19 or Multisystem Inflammatory Syndrome in Children and Adolescents. View Abstract
Measurement of Severe Acute Respiratory Syndrome Coronavirus 2 Antigens in Plasma of Pediatric Patients With Acute Coronavirus Disease 2019 or Multisystem Inflammatory Syndrome in Children Using an Ultrasensitive and Quantitative Immunoassay. View Abstract
Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. View Abstract
COVID-19 and children. View Abstract
Investigating Health Disparities Associated With Multisystem Inflammatory Syndrome in Children After SARS-CoV-2 Infection. View Abstract
Health Impairments in Children and Adolescents After Hospitalization for Acute COVID-19 or MIS-C. View Abstract
SARS-CoV-2-specific T cell responses in patients with multisystem inflammatory syndrome in children. View Abstract
Vaccine Effectiveness Against Life-Threatening Influenza Illness in US Children. View Abstract
Author Correction: Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. View Abstract
Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies. View Abstract
Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants. View Abstract
A Description of COVID-19-Directed Therapy in Children Admitted to US Intensive Care Units 2020. View Abstract
Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C. View Abstract
Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. View Abstract
BNT162b2 Protection against the Omicron Variant in Children and Adolescents. View Abstract
Resuscitation Fluid Composition and Acute Kidney Injury in Critical Illness. View Abstract
Candidacy for Extracorporeal Life Support in Children After Hematopoietic Cell Transplantation: A Position Paper From the Pediatric Acute Lung Injury and Sepsis Investigators Network's Hematopoietic Cell Transplant and Cancer Immunotherapy Subgroup. View Abstract
Frequency, Characteristics and Complications of COVID-19 in Hospitalized Infants. View Abstract
Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19-Associated Hospitalization in Infants Aged <6 Months - 17 States, July 2021-January 2022. View Abstract
Systemic and Lower Respiratory Tract Immunity to SARS-CoV-2 Omicron and Variants in Pediatric Severe COVID-19 and Mis-C. View Abstract
Immunology of SARS-CoV-2 infection in children. View Abstract
Effectiveness of BNT162b2 (Pfizer-BioNTech) mRNA Vaccination Against Multisystem Inflammatory Syndrome in Children Among Persons Aged 12-18 Years - United States, July-December 2021. View Abstract
Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents. View Abstract
Optical genome mapping identifies rare structural variations as predisposition factors associated with severe COVID-19. View Abstract
Severe COVID-19 and Multisystem Inflammatory Syndrome in Children in Children and Adolescents. View Abstract
An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2. View Abstract
Multisystem Inflammatory-like Syndrome in a Child Following COVID-19 mRNA Vaccination. View Abstract
Modeling the Impacts of Clinical Influenza Testing on Influenza Vaccine Effectiveness Estimates. View Abstract
Measurement of SARS-CoV-2 antigens in plasma of pediatric patients with acute COVID-19 or MIS-C using an ultrasensitive and quantitative immunoassay. View Abstract
Surfactant protein D is a biomarker of influenza-related pediatric lung injury. View Abstract
Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12-18 Years - United States, June-September 2021. View Abstract
Estimated Pao2: A Continuous and Noninvasive Method to Estimate Pao2 and Oxygenation Index. View Abstract
Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents. View Abstract
Therapy for Multisystem Inflammatory Syndrome in Children. Reply. View Abstract
Rate of thrombosis in children and adolescents hospitalized with COVID-19 or MIS-C. View Abstract
Mechanisms underlying genetic susceptibility to multisystem inflammatory syndrome in children (MIS-C). View Abstract
Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain. View Abstract
Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes. View Abstract
Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions. View Abstract
Variation in Intravenous Acetaminophen Use in Pediatric Hospitals: Priorities for Standardization. View Abstract
Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2. View Abstract
Incorporating Real-time Influenza Detection Into the Test-negative Design for Estimating Influenza Vaccine Effectiveness: The Real-time Test-negative Design (rtTND). View Abstract
Sepsis Subclasses: A Framework for Development and Interpretation. View Abstract
Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. View Abstract
Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19. View Abstract
Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4. View Abstract
Exuberant fibroblast activity compromises lung function via ADAMTS4. View Abstract
Multisystem Inflammatory Syndrome in Children in the United States. Reply. View Abstract
Inclusion of Children in Clinical Trials of Treatments for Coronavirus Disease 2019 (COVID-19). View Abstract
Pediatric Cardiac Intensive Care Distribution, Service Delivery, and Staffing in the United States in 2018. View Abstract
Immune dysregulation and multisystem inflammatory syndrome in children (MIS-C) in individuals with haploinsufficiency of SOCS1. View Abstract
Machine Learning Predicts Prolonged Acute Hypoxemic Respiratory Failure in Pediatric Severe Influenza. View Abstract
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. View Abstract
Early Amplified Respiratory Bioactive Lipid Response Is Associated With Worse Outcomes in Pediatric Influenza-Related Respiratory Failure. View Abstract
RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness. View Abstract
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract
Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract
Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract
Growth and Changing Characteristics of Pediatric Intensive Care 2001-2016. View Abstract
The authors reply. View Abstract
A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. View Abstract
Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness. View Abstract
Cost Implications of Escalating Intravenous Acetaminophen Use in Children. View Abstract
Acute respiratory distress syndrome. View Abstract
Antibiotic Prescription in Young Children With Respiratory Syncytial Virus-Associated Respiratory Failure and Associated Outcomes. View Abstract
Vancomycin Monotherapy May Be Insufficient to Treat Methicillin-resistant Staphylococcus aureus Coinfection in Children With Influenza-related Critical Illness. View Abstract
Cytokine Profiles of Severe Influenza Virus-Related Complications in Children. View Abstract
A Biosignature Predicting Complicated Course in Children Presenting with Septic Shock. Why PERSEVERE? View Abstract
SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans. View Abstract
Simulation of a Novel Schedule for Intensivist Staffing to Improve Continuity of Patient Care and Reduce Physician Burnout. View Abstract
Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection. View Abstract
Why So Few Randomized Trials in Pediatric Critical Care Medicine? Ask the Trialists. View Abstract
Mannose-Binding Lectin Levels in Critically Ill Children With Severe Infections. View Abstract
1444: MANNOSE-BINDING LECTIN AND PEDIATRIC SEPSIS SUSCEPTIBILITY: A SYSTEMATIC REVIEW AND META-ANALYSIS. View Abstract
933: ASSOCIATIONS BETWEEN PNEUMONIA AND CLINICAL OUTCOMES IN PICU PATIENTS WITH RSV BRONCHIOLITIS. View Abstract
Enterovirus D68 Reemerges Globally as a Severe Pathogen Targeting Children. View Abstract
Determinants of red blood cell transfusion in pediatric trauma patients admitted to the intensive care unit. View Abstract
Staphylococcus aureus a-Toxin Response Distinguishes Respiratory Virus-Methicillin-Resistant S. aureus Coinfection in Children. View Abstract
The Impact of Clinical Trials Conducted by Research Networks in Pediatric Critical Care. View Abstract
High Variability in the Reported Management of Hepatic Veno-Occlusive Disease in Children after Hematopoietic Stem Cell Transplantation. View Abstract
The authors reply. View Abstract
Incidence and risk factors for postoperative vomiting following atrial septal defect repair in children. View Abstract
Optimizing Virus Identification in Critically Ill Children Suspected of Having an Acute Severe Viral Infection. View Abstract
Pragmatic trials in critically ill children are CATCHing on. View Abstract
Anesthesiologist- and System-Related Risk Factors for Risk-Adjusted Pediatric Anesthesia-Related Cardiac Arrest. View Abstract
Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis? View Abstract
Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy. View Abstract
Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D. View Abstract
Therapeutic Hypothermia in Children. View Abstract
Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome? View Abstract
Recognizing and managing sepsis: what needs to be done? View Abstract
The tremendous burden of sepsis on China's youngest children. View Abstract
Variability in IRBs regarding parental acceptance of passive consent. View Abstract
More consistent site institutional review board (IRB) input-more consistent site IRB output. View Abstract
A multinational study of thromboprophylaxis practice in critically ill children. View Abstract
Effectiveness of influenza vaccine against life-threatening RT-PCR-confirmed influenza illness in US children, 2010-2012. View Abstract
The authors reply. View Abstract
Vitamin D-binding protein haplotype is associated with hospitalization for RSV bronchiolitis. View Abstract
Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU. View Abstract
Rigorous scoping review of randomized trials in pediatric critical care highlights need for a rigorous rethink. View Abstract
Pediatric sepsis: important considerations for diagnosing and managing severe infections in infants, children, and adolescents. View Abstract
The authors reply. View Abstract
Mechanical ventilation strategies in children with acute lung injury: a survey on stated practice pattern*. View Abstract
The authors reply. View Abstract
Innate immune function and mortality in critically ill children with influenza: a multicenter study. View Abstract
A pilot, randomized, controlled clinical trial of lucinactant, a peptide-containing synthetic surfactant, in infants with acute hypoxemic respiratory failure. View Abstract
Risk factors for mechanical ventilation in U.S. children hospitalized with seasonal influenza and 2009 pandemic influenza A*. View Abstract
Fluid balance in critically ill children with acute lung injury. View Abstract
Vitamin D deficiency in critically ill children. View Abstract
Critical illness from 2009 pandemic influenza A virus and bacterial coinfection in the United States. View Abstract
Impact of a conservative red blood cell transfusion strategy in children undergoing hematopoietic stem cell transplantation. View Abstract
Critically ill children during the 2009-2010 influenza pandemic in the United States. View Abstract
Survey of pharmacologic thromboprophylaxis in critically ill children. View Abstract
Summary of recommendations: Guidelines for the Prevention of Intravascular Catheter-related Infections. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. View Abstract
Central venous line thromboprophylaxis: transforming "experience-based care" into "evidence-based care". View Abstract
Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. View Abstract
Risk factors for central line-associated bloodstream infection in pediatric intensive care units. View Abstract
WITHDRAWN: Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. View Abstract
Association between length of storage of red blood cell units and outcome of critically ill children: a prospective observational study. View Abstract
Early observational research and registries during the 2009-2010 influenza A pandemic. View Abstract
Steroids for post extubation stridor: pediatric evidence is still inconclusive. View Abstract
Beyond mortality: future clinical research in acute lung injury. View Abstract
Clinical prediction rules: new opportunities for pharma. View Abstract
No child left behind: Enrolling children and adults simultaneously in critical care randomized trials. View Abstract
Management of acute lung injury and acute respiratory distress syndrome in children. View Abstract
Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. View Abstract
The unique challenges of enrolling patients into multiple clinical trials. View Abstract
Addressing the unit of analysis in medical care studies: a systematic review. View Abstract
Anemia, blood loss, and blood transfusions in North American children in the intensive care unit. View Abstract
Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. View Abstract
Gender differences in research grant applications and funding outcomes for medical school faculty. View Abstract
The financial impact of underestimating personnel needs associated with implementing a computerized patient record in the intensive care unit. View Abstract
Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. View Abstract
Surfactant therapy for acute respiratory failure in children: a systematic review and meta-analysis. View Abstract
Real-time evaluation of patient monitoring algorithms for critical care at the bedside. View Abstract
Potential for donation after cardiac death in a children's hospital. View Abstract
Cumulative fluid intake minus output is not associated with ventilator weaning duration or extubation outcomes in children. View Abstract
Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes. View Abstract
Identification of central venous catheter-related infections in infants and children. View Abstract
Genetic polymorphisms in sepsis. View Abstract
Assessing the quality of case-control association studies on the genetic basis of sepsis. View Abstract
International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. View Abstract
Risk of bacterial infection in previously healthy respiratory syncytial virus-infected young children admitted to the intensive care unit. View Abstract
Ribavirin for respiratory syncytial virus infection of the lower respiratory tract in infants and young children. View Abstract
Effect of lung compliance and endotracheal tube leakage on measurement of tidal volume. View Abstract
Efficacy of interventions for bronchiolitis in critically ill infants: a systematic review and meta-analysis. View Abstract
The IL12B gene is associated with asthma. View Abstract
Growth of pediatric intensive care units in the United States from 1995 to 2001. View Abstract
All roses are flowers, but not all flowers are roses. View Abstract
How are children mechanically ventilated in pediatric intensive care units? View Abstract
IL10 gene polymorphisms are associated with asthma phenotypes in children. View Abstract
IL-10 gene polymorphisms are associated with asthma phenotypes in children View Abstract
Effect of endotracheal tube leak and lung compliance on measurement of tidal volume in children View Abstract
How are children mechanically ventilated in PICUs? View Abstract
International Pediatric Sepsis Consensus Conference: Definitions for sepsis and organ dysfunction in pediatrics View Abstract
A practical approach to evidence-based medicine: lessons learned from developing ventilator management protocols. View Abstract
Central line complications in an infant View Abstract
Pediatric critical care medicine: planning for our research future. View Abstract
The feasibility of conducting clinical trials in infants and children with acute respiratory failure. View Abstract
for the Pediatric Acute Lung Injury and Sepsis Investigator’s Network. The feasibility of conducting clinical trials in infants and children with acute respiratory failure View Abstract
Preventing central venous catheter-related complications. In Evidence-Based Resource in Anaesthesia and Analgesia, Editor: Martin R. Tramer View Abstract
Association between IL12B polymorphisms in the CAMP study View Abstract
Guidelines for the prevention of intravascular catheter-related infections. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. View Abstract
Effect of mechanical ventilator weaning protocols on respiratory outcomes in infants and children: a randomized controlled trial. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. The Hospital Infection Control Practices Advisory Committee, Center for Disease Control and Prevention, U.S. View Abstract
Guidelines for the prevention of intravascular catheter-related infections. Centers for Disease Control and Prevention. View Abstract
What underlies race and sex differences in acute respiratory distress syndrome-associated mortality? View Abstract
Corticosteroids for the prevention of reintubation and postextubation stridor in pediatric patients: A meta-analysis. View Abstract
Mining for the genetic determinants of septic shock: when is it really gold? View Abstract
Randomized clinical trials in pediatric critical care: Rarely done but desperately needed. View Abstract
Reorganizing the delivery of intensive care could improve efficiency and save lives. View Abstract
Measured tidal volume is influenced by lung compliance View Abstract
for the Pediatric Acute Lung Injury and Sepsis Investigator’s Network. Weaning critically ill children from ventilator support: a randomized trial comparing two protocols to standard care View Abstract
Measuring the health status of pediatric intensive care unit survivors View Abstract
What underlies racial and gender differences in ARDS-associated mortality? View Abstract
Corticosteroids for the prevention of reintubation and post-extubation stridor in pediatric patients: a meta-analysis View Abstract
Reorganising the delivery of intensive care could improve efficiency and save lives View Abstract
Guidelines for the prevention of intravascular catheter-related infections View Abstract
Upper gastrointestinal bleeding in the pediatric intensive care unit: clinically important but questionably preventable. View Abstract
Tidal volume (VT) is most accurately measured at the endotracheal tube when lung compliance is poor View Abstract
Therapy and validity: Computer Decision Support Systems. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature View Abstract
Systematic review of treatments for critically ill infants with bronchiolitis View Abstract
Randomized clinical trials in pediatric critical care View Abstract
Prognosis. In: Guyatt G, Rennie D, editors. Users’ guides to the medical literature View Abstract
Evaluation of a pediatric extubation readiness test View Abstract
Ribavirin for respiratory syncytial virus infection of the lower respiratory tract. View Abstract
Corticosteroids for the prevention and treatment of post-extubation stridor in neonates, children and adults. View Abstract
Users' Guides to the Medical Literature: XVIII. How to use an article evaluating the clinical impact of a computer-based clinical decision support system. View Abstract
Reorganizing the delivery of intensive care may improve patient outcomes. View Abstract
Variability in physician opinion on limiting pediatric life support. View Abstract
Is informed consent always necessary for randomized, controlled trials? . View Abstract
Single versus multilumen central venous catheters: a critical appraisal of the infection risk View Abstract
The Pediatric Critical Care Evidence-Based Internet Journal Club: interim evaluation View Abstract
Weaning from mechanical ventilation View Abstract
Antiseptic hub connectors reduce central venous catheter-related sepsis View Abstract
Efficacy of continuous vs. intermittent furosemide View Abstract
Outcome of out-of-hospital pediatric pulseless arrest View Abstract
Evaluation of compliance with a computerized protocol: weaning from mechanical ventilator support using pressure support. View Abstract
Understanding articles describing clinical prediction tools. Evidence Based Medicine in Critical Care Group. View Abstract
Tunneling short-term central venous catheters to prevent catheter-related infection: a meta-analysis of randomized, controlled trials. View Abstract
An evidence-based approach to central venous catheter management to prevent catheter-related infection in critically ill patients. View Abstract
Prognosis in the intensive care unit: finding accurate and useful estimates for counseling patients. View Abstract
Understanding articles comparing outcomes among intensive care units to rate quality of care. Evidence Based Medicine in Critical Care Group. View Abstract
Benefit of heparin in peripheral venous and arterial catheters: systematic review and meta-analysis of randomised controlled trials. View Abstract
Benefit of heparin in central venous and pulmonary artery catheters: a meta-analysis of randomized controlled trials. View Abstract
Clinical prediction guides. View Abstract
Potential for meeting clinician information requirements in an intensive care unit (ICU) via the web. View Abstract
Tunneling of central venous catheters: a meta-analysis of randomized controlled trials View Abstract
Cost-effectiveness of 10 strategies for managing suspected central venous catheter-related infections View Abstract
Understanding articles describing clinical prediction tools View Abstract
Positive predictive value of bilateral absence of somatosensory evoked potentials in severe traumatic brain injury View Abstract
Variability in physician opinion on limiting pediatric life support. URL
http://www.pediatrics.org/cgi/content/full/103/4/e46 View Abstract
Clinical Prediction Guidelines View Abstract
An evidence based approach to central venous catheter management View Abstract
Central venous catheter replacement strategies: a systematic review of the literature. View Abstract
Factors explaining variability among caregivers in the intent to restrict life-support interventions in a pediatric intensive care unit. View Abstract
Paediatric index of mortality (PIM): do we need another paediatric mortality prediction score? View Abstract
Critical appraisal of “UK collaborative randomized trial of neonatal extracorporeal membrane oxygenation” by the UK Collaborative ECMO Trial Group View Abstract
Resources for applying evidence based medicine in the Pediatric Intensive Care Unit (PICU) View Abstract
The critical care database of randomized controlled trials: A resource to facilitate evidence-based practice in the intensive care unit View Abstract
Critical appraisal of “Outcome of out-of-hospital cardiac or respiratory arrest in children” by MB Schindler et al View Abstract
Central venous catheter exchange strategies: a meta-analysis of randomized controlled trials View Abstract
Critical appraisal of “Dexamethasone in the prevention of postextubation stridor in children” by DW Tellez et al View Abstract
Critical appraisal of “Diagnosis and treatment of ventilator-associated pneumonia—impact on survival” by TR Sterling et al View Abstract
Critical appraisal of “Dexamethasone for the prevention of postextubation airway obstruction: a prospective, randomized, double-blind, placebo-controlled trial” by O. Anene et al View Abstract
Pediatric intensive care units in 1995;numbers, characteristics, and distribution View Abstract
Ultrasound guidance for placement of central venous catheters: a meta-analysis of the literature. View Abstract
Acyclovir prophylaxis in late pregnancy to prevent neonatal herpes: a cost-effectiveness analysis. View Abstract
Ribavirin for respiratory syncytial virus lower respiratory tract infection. A systematic overview. View Abstract
Testing and validation of computerized decision support systems. View Abstract
A computerized protocol for weaning patients from mechanical ventilation using the pressure support mode View Abstract
Ribavirin for respiratory syncytial virus lower respiratory tract infection: a systematic overview View Abstract
Learning airway management skills: guidelines for pediatrics. View Abstract
Learning airway management skills: guidelines for pediatrics View Abstract
Cesarean delivery for women presenting with genital herpes lesions. Efficacy, risks, and costs. View Abstract
Screening for Chlamydia trachomatis in adolescent males: a cost-based decision analysis. View Abstract
Screening for Chlamydia trachomatis in adolescent males: cost and benefits of the leukocyte esterase urine dipstick test View Abstract
Cerebral hemisphere involvement in recognizing nonsense words, and in matching picture patterns and facial emotions View Abstract