Chellamani Harini, MD
Director, Infantile Spasms Program; Neurologist, Department of Neurology
Assistant Professor of Neurology, Harvard Medical School
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Chellamani Harini, MD
Director, Infantile Spasms Program; Neurologist, Department of Neurology
Assistant Professor of Neurology, Harvard Medical School
Medical Services
Education
Medical School
Madras Medical College
1989
Madras
India
Internship
Government General Hospital, Madras Medical College
1989
Madra
India
Internship
Henry Ford Hospital
1996
Detriot
MI
Residency
Pediatrics
Henry Ford Hospital
2000
Detroit
MI
Residency
Child Neurology
Tufts New England Medical Center
2005
Boston
MA
Fellowship
Epilepsy and Neurophysiology
Boston Children's Hospital
2006
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
American Board of Psychiatry and Neurology (Epilepsy)
American Board of Clinical Neurophysiology
Professional History
Dr. Harini serves as an expert for the Department of Neurology for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit bostonchildrens.org/precisionmed.
Publications
Evaluating the effectiveness of medical therapy in infantile epileptic spasms syndrome due to surgically-remediable lesions. View Abstract
Outcomes following resective and disconnective strategies in the treatment of epileptic spasms: a systematic review of the literature and individual patient data meta-analysis. View Abstract
Infantile-Onset Epilepsies: Steering Towards New Horizons. View Abstract
A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome. View Abstract
A Multicenter Training and Interrater Reliability Study of the BASED Score for Infantile Epileptic Spasms Syndrome. View Abstract
The spectrum of movement disorders in young children with ARX-related epilepsy-dyskinesia syndrome. View Abstract
Diagnostic Yield of CSF Testing in Infants for Disorders of Biogenic Amine Neurotransmitter Metabolism. View Abstract
Timing the clinical onset of epileptic spasms in infantile epileptic spasms syndrome: A tertiary health center's experience. View Abstract
Initial combination versus early sequential standard therapies for Infantile Epileptic Spasms Syndrome-Feedback from stakeholders. View Abstract
Delays to care in infantile epileptic spasms syndrome: Racial and ethnic inequities. View Abstract
Post-zygotic rescue of meiotic errors causes brain mosaicism and focal epilepsy. View Abstract
Influence of extent and age at corpus callosotomy on seizure outcomes. A single center experience. View Abstract
Epileptic spasms in CDKL5 deficiency disorder: Delayed treatment and poor response to first-line therapies. View Abstract
Hospital readmissions in children with new-onset infantile epileptic spasms syndrome. View Abstract
Clinical characteristics of children with infantile epileptic spasms syndrome from a tertiary-care hospital in Dhaka, Bangladesh. View Abstract
Temporal trends in the cost and use of first-line treatments for infantile epileptic spasms syndrome. View Abstract
Association of Time to Clinical Remission With Sustained Resolution in Children With New-Onset Infantile Spasms. View Abstract
Interictal Connectivity Revealed by Granger Analysis of Stereoelectroencephalography: Association With Ictal Onset Zone, Resection, and Outcome. View Abstract
Inequities in Therapy for Infantile Spasms: A Call to Action. View Abstract
Infantile spasms: Assessing the diagnostic yield of an institutional guideline and the impact of etiology on long-term treatment response. View Abstract
Comparison of Cosyntropin, Vigabatrin, and Combination Therapy in New-Onset Infantile Spasms in a Prospective Randomized Trial. View Abstract
Confirmation of infantile spasms resolution by prolonged outpatient EEGs. View Abstract
Comparative Effectiveness of Initial Treatment for Infantile Spasms in a Contemporary US Cohort. View Abstract
Subclinical seizures detected on intracranial EEG: Patient characteristics and impact on surgical outcome in a single pediatric epilepsy surgery center. View Abstract
Hippocampal Involvement With Vigabatrin-Related MRI Signal Abnormalities in Patients With Infantile Spasms: A Novel Finding. View Abstract
Cost-effectiveness of adrenocorticotropic hormone versus oral steroids for infantile spasms. View Abstract
Management of Infantile Spasms During the COVID-19 Pandemic. View Abstract
Crisis Standard of Care: Management of Infantile Spasms during COVID-19. View Abstract
Mortality in infantile spasms: A hospital-based study. View Abstract
Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. View Abstract
Brain MRI abnormalities in patients with infantile spasms and Down syndrome. View Abstract
Detailed Magnetic Resonance Imaging (MRI) Analysis in Infantile Spasms. View Abstract
White matter spongiosis with vigabatrin therapy for infantile spasms. View Abstract
Seizure clustering during presurgical electroencephalographic monitoring in children. View Abstract
Brain tumors and epileptic spasms: Natural history and outcomes. View Abstract
Patterns of Head Computed Tomography Abnormalities During Pediatric Extracorporeal Membrane Oxygenation and Association With Outcomes. View Abstract
Expanding the phenotypic spectrum of GABRG2 variants: a recurrent GABRG2 missense variant associated with a severe phenotype. View Abstract
A pediatric epilepsy diagnostic tool for use in resource-limited settings: A pilot study. View Abstract
Effectiveness of once-daily high-dose ACTH for infantile spasms. View Abstract
Utility of initial EEG in first complex febrile seizure. View Abstract
Clinical and Neuroimaging Profile of Children with Lesions in the Corpus Callosum. View Abstract
Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. View Abstract
Localization of the epileptogenic foci in tuberous sclerosis complex: a pediatric case report. View Abstract
Rasmussen's encephalitis presenting as focal cortical dysplasia. View Abstract
Clobazam: effect on frequency of seizures and safety profile in different subgroups of children with epilepsy. View Abstract
Neurological maturation of late preterm infants at 34?wk assessed by amplitude integrated electroencephalogram. View Abstract
Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management. View Abstract
Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. View Abstract
Predictors of seizure occurrence in children undergoing pre-surgical monitoring. View Abstract
Teaching NeuroImages: mesial temporal sclerosis after a prolonged unprovoked seizure in an infant. View Abstract
Transient suppression of seizures by repetitive transcranial magnetic stimulation in a case of Rasmussen's encephalitis. View Abstract
Locations