Dario Fauza, MD, PhD
Fellowship Co-Director, Surgical Research Laboratories
Associate Professor of Surgery, Harvard Medical School
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Dario Fauza, MD, PhD
Fellowship Co-Director, Surgical Research Laboratories
Associate Professor of Surgery, Harvard Medical School
Medical Services
Languages
English
Portuguese
Education
Medical School
University of Sao Paulo
1985
Brazil
Internship
Hospital of Clinics of the University of Sao Paulo Medical School
1986
San Paulo
Brazil
Residency
Hospital of Clinics / Children's Hospital of the University of Sao Paulo Medical School
1991
San Paulo
Brazil
Fellowship
Boston Children's Hospital
1997
Boston
MA
Fellowship
Boston Children's Hospital
2000
Boston
MA
Professional History
Dario Fauza received MD and PhD degrees from the University of Sao Paulo, in Brazil, where he also attended internship and residencies in general and pediatric surgery. He then moved to the United States in the 1990’s, where he completed further training in different clinical and postdoctoral fellowships, all at Boston Children's Hospital and Harvard Medical School. He is currently a staff member of Boston Children's Hospital’s Department of Surgery, as well as an Associate Professor of Surgery at Harvard Medical School.
He has a prolific bibliography and is the recipient of multiple awards and honors in the United States and abroad. He has pioneered novel cell-based strategies for the treatment of congenital diseases, including the principles of fetal tissue engineering in parallel to gestation and of transamniotic stem cell therapy (TRASCET), among others. He has an extensive record of mentoring surgical trainees who went on to successful careers in Pediatric Surgery.
Publications
Bidirectional Feto-Maternal Traffic of Donor Mesenchymal Stem Cells Following Transamniotic Stem Cell Therapy (TRASCET). View Abstract
Morphometric, Developmental, and Anti-Inflammatory Effects of Transamniotic Stem Cell Therapy (TRASCET) on the Fetal Heart and Lungs in a Model of Intrauterine Growth Restriction. View Abstract
Hematogenous Routing of Exogenous Messenger RNA Delivered Into the Amniotic Fluid. View Abstract
Fetal Secretory IgA Delivery via Transamniotic Fetal Immunotherapy (TRAFIT) in a Rodent Model. View Abstract
Transamniotic stem cell therapy (TRASCET): An emerging minimally invasive strategy for intrauterine stem cell delivery. View Abstract
Transamniotic Fetal Administration of Genetically Modified Hematopoietic Stem Cells Carrying a Human Transgene in a Syngeneic Rat Model. View Abstract
Invited Commentary for Disruption of Enterohepatic Circulation of Bile Acids Ameliorates Small Bowel Resection Associated Hepatic Injury. View Abstract
Fetal Alloimmune Hemolytic Anemia (AHA) as a Potential Target for Transamniotic Fetal Immunotherapy (TRAFIT). View Abstract
Transamniotic stem cell therapy (TRASCET) for intrauterine growth restriction (IUGR): A comparison between placental and amniotic fluid donor mesenchymal stem cells. View Abstract
Brain protection by transamniotic stem cell therapy (TRASCET) in a model of intrauterine growth restriction (IUGR). View Abstract
Early functional analysis on the pulmonary hemodynamic effects of Transamniotic Stem Cell Therapy (TRASCET) in the nitrofen model of congenital diaphragmatic hernia. View Abstract
Invited Commentary. View Abstract
Routing kinetics of human immunoglobulin-G after transamniotic fetal immunotherapy (TRAFIT) in a rodent model. View Abstract
Intrauterine Growth Restriction (IUGR) as a potential target for transamniotic stem cell therapy. View Abstract
Routing pathway of syngeneic donor hematopoietic stem cells after simple intra-amniotic delivery. View Abstract
Passive perinatal immunotherapy via transamniotic antibody delivery. View Abstract
Wound healing potential of human umbilical cord mesenchymal stem cell conditioned medium: An in vitro and in vivo study in diabetes-induced rats. View Abstract
Unselected CD117 expression in amniotic and placental mesenchymal stem cells. View Abstract
Transamniotic Stem Cell Therapy for Experimental Congenital Diaphragmatic Hernia: Structural, Transcriptional, and Cell Kinetics Analyses in the Nitrofen Model. View Abstract
Enhancement of transamniotic stem cell therapy for spina bifida by genetic engineering of donor mesenchymal stem cells with an Fgf2 transgene. View Abstract
Fetal hematogenous routing of a donor hematopoietic stem cell line in a healthy syngeneic model of transamniotic stem cell therapy. View Abstract
A novel two-component, expandable bioadhesive for exposed defect coverage: Applicability to prenatal procedures. View Abstract
Initial Mechanistic Screening of Transamniotic Stem Cell Therapy in the Rodent Model of Spina Bifida: Host Bone Marrow and Paracrine Activity. View Abstract
Hematogenous Donor Cell Routing Pathway After Transamniotic Stem Cell Therapy. View Abstract
Postnatal fate of donor mesenchymal stem cells after transamniotic stem cell therapy in a healthy model. View Abstract
Transamniotic Stem Cell Therapy. View Abstract
Donor mesenchymal stem cell kinetics after transamniotic stem cell therapy (TRASCET) in a rodent model of gastroschisis. View Abstract
Congenital diaphragmatic hernia as a potential target for transamniotic stem cell therapy. View Abstract
A comparison between placental and amniotic mesenchymal stem cells in transamniotic stem cell therapy for experimental gastroschisis. View Abstract
An experimental study on magnetic esophageal compression anastomosis in piglets. View Abstract
Transamniotic stem cell therapy (TRASCET) in a rabbit model of spina bifida. View Abstract
A comparison of clinically relevant sources of mesenchymal stem cell-derived exosomes: Bone marrow and amniotic fluid. View Abstract
Donor mesenchymal stem cell linetics after transamniotic stem cell therapy (TRASCET) for experimental spina bifida. View Abstract
Regenerative medicine and spina bifida: Recent developments in induced fetal regeneration. View Abstract
Fetal bone marrow homing of donor mesenchymal stem cells after transamniotic stem cell therapy (TRASCET). View Abstract
Transamniotic stem cell therapy: a novel strategy for the prenatal management of congenital anomalies. View Abstract
Donor mesenchymal stem cells home to maternal wounds after transamniotic stem cell therapy (TRASCET) in a rodent model. View Abstract
Comparisons of human amniotic mesenchymal stem cell viability in FDA-approved collagen-based scaffolds: Implications for engineered diaphragmatic replacement. View Abstract
Transamniotic stem cell therapy (TRASCET) in a leporine model of gastroschisis. View Abstract
A comparison between placental and amniotic mesenchymal stem cells for transamniotic stem cell therapy (TRASCET) in experimental spina bifida. View Abstract
Transamniotic stem cell therapy (TRASCET) mitigates bowel damage in a model of gastroschisis. View Abstract
Trans-amniotic stem cell therapy (TRASCET) minimizes Chiari-II malformation in experimental spina bifida. View Abstract
Extraluminal distraction enterogenesis using shape-memory polymer. View Abstract
Limb reconstruction with decellularized, non-demineralized bone in a young leporine model. View Abstract
Partial or complete coverage of experimental spina bifida by simple intra-amniotic injection of concentrated amniotic mesenchymal stem cells. View Abstract
Operative indications in recurrent ileocolic intussusception. View Abstract
Extraluminal helicoidal stretch (Helixtretch): a novel method of intestinal lengthening. View Abstract
The impact of gestational age on targeted amniotic cell profiling in experimental neural tube defects. View Abstract
Tissue engineering in congenital diaphragmatic hernia. View Abstract
A comparative analysis of human mesenchymal stem cell response to hypoxia in vitro: Implications to translational strategies. View Abstract
Targeted quantitative amniotic cell profiling: a potential diagnostic tool in the prenatal management of neural tube defects. View Abstract
Intra-amniotic delivery of amniotic-derived neural stem cells in a syngeneic model of spina bifida. View Abstract
Pediatric postoperative intussusception in the minimally invasive surgery era: a 13-year, single center experience. View Abstract
The amniotic fluid as a source of neural stem cells in the setting of experimental neural tube defects. View Abstract
Prenatal tracheal reconstruction with a hybrid amniotic mesenchymal stem cells-engineered construct derived from decellularized airway. View Abstract
Craniofacial repair with fetal bone grafts engineered from amniotic mesenchymal stem cells. View Abstract
Preclinical regulatory validation of an engineered diaphragmatic tendon made with amniotic mesenchymal stem cells. View Abstract
Serial amnioinfusions prevent fetal pulmonary hypoplasia in a large animal model of oligohydramnios. View Abstract
Amniotic and placental mesenchymal stem cell isolation and culture. View Abstract
Amniotic mesenchymal stem cells enhance normal fetal wound healing. View Abstract
Structural and biomechanical characteristics of the diaphragmatic tendon in infancy and childhood: an initial analysis. View Abstract
Correlation between prenatal urinary matrix metalloproteinase activity and the degree of kidney damage in a large animal model of congenital obstructive uropathy. View Abstract
Chest wall repair with engineered fetal bone grafts: an efficacy analysis in an autologous leporine model. View Abstract
A large animal model of the fetal tracheal stenosis/atresia spectrum. View Abstract
Prenatal urinary matrix metalloproteinase profiling as a potential diagnostic tool in fetal obstructive uropathy. View Abstract
Optical properties of human amniotic fluid: implications for videofetoscopic surgery. View Abstract
Sternal repair with bone grafts engineered from amniotic mesenchymal stem cells. View Abstract
Fetal tissue engineering. View Abstract
Differential risk for neonatal surgical airway intervention in prenatally diagnosed neck masses. View Abstract
Preservation of intestinal motility after the serial transverse enteroplasty procedure in a large animal model of short bowel syndrome. View Abstract
Neural stem cell delivery to the spinal cord in an ovine model of fetal surgery for spina bifida. View Abstract
Preclinical regulatory validation of a 3-stage amniotic mesenchymal stem cell manufacturing protocol. View Abstract
Extracorporeal membrane oxygenation as a bridge to definitive tracheal reconstruction in neonates. View Abstract
Liver position is a prenatal predictive factor of prosthetic repair in congenital diaphragmatic hernia. View Abstract
Autologous Approaches to Tissue Engineering View Abstract
A comparative analysis of cartilage engineered from different perinatal mesenchymal progenitor cells. View Abstract
Tissue engineering from human mesenchymal amniocytes: a prelude to clinical trials. View Abstract
Isolation of mesenchymal stem cells from amniotic fluid and placenta. View Abstract
Large fetal congenital cystic adenomatoid malformations: growth trends and patient survival. View Abstract
Ex utero intrapartum treatment with placement on extracorporeal membrane oxygenation for fetal thoracic masses. View Abstract
Ex utero intrapartum treatment with extracorporeal membrane oxygenation for severe congenital diaphragmatic hernia. View Abstract
Percent predicted lung volumes as measured on fetal magnetic resonance imaging: a useful biometric parameter for risk stratification in congenital diaphragmatic hernia. View Abstract
The second STEP: the feasibility of repeat serial transverse enteroplasty. View Abstract
Fetal hepatic haematopoiesis is modulated by arterial blood flow to the liver. View Abstract
Postnatal myocardial augmentation with skeletal myoblast-based fetal tissue engineering. View Abstract
Hyperoncotic enhancement of fetal pulmonary growth after tracheal occlusion: an alveolar and capillary morphometric analysis. View Abstract
Fetal tracheal reconstruction with cartilaginous grafts engineered from mesenchymal amniocytes. View Abstract
Extracellular matrix dynamics associated with tissue-engineered intravascular sclerotherapy. View Abstract
Fetal cartilage engineering from amniotic mesenchymal progenitor cells. View Abstract
Serial transverse enteroplasty enhances intestinal function in a model of short bowel syndrome. View Abstract
Diaphragmatic repair through fetal tissue engineering: a comparison between mesenchymal amniocyte- and myoblast-based constructs. View Abstract
Bronchial atresia: the hidden pathology within a spectrum of prenatally diagnosed lung masses. View Abstract
In vitro cartilage regeneration from proliferated adult elastic chondrocytes. View Abstract
Cartilage engineering from ovine umbilical cord blood mesenchymal progenitor cells. View Abstract
Pneumonectomy in the mouse: technique and perioperative management. View Abstract
An injectable tissue-engineered embolus prevents luminal recanalization after vascular sclerotherapy. View Abstract
Enhancement of intravascular sclerotherapy by tissue engineering: short-term results. View Abstract
Intratracheal pulmonary ventilation improves gas exchange during laparoscopy in a pediatric lung injury model. View Abstract
Amniotic fluid and placental stem cells. View Abstract
In situ inhibition of uterine activity by indomethacin: possible relevance to preterm labor prevention after fetal surgery. View Abstract
Diaphragmatic reconstruction with autologous tendon engineered from mesenchymal amniocytes. View Abstract
Rapidly polymerizing hydrogel prevents balloon dislodgement in a model of fetal tracheal occlusion. View Abstract
Hyperoncotic enhancement of pulmonary growth after fetal tracheal occlusion: a comparison between dextran and albumin. View Abstract
Local anesthetics inhibit uterine activity in vitro. Possible application on preterm labor prevention and treatment. View Abstract
Fetal tissue engineering: in vitro analysis of muscle constructs. View Abstract
Fetal tissue engineering: chest wall reconstruction. View Abstract
Serial transverse enteroplasty for short bowel syndrome: a case report. View Abstract
Fetal tracheal augmentation with cartilage engineered from bone marrow-derived mesenchymal progenitor cells. View Abstract
Tissue engineering: current state of clinical application. View Abstract
Fetal tissue engineering from amniotic fluid. View Abstract
Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure. View Abstract
Clostridium botulinum toxin inhibits myometrial activity in vitro: possible application on the prevention of preterm labor after fetal surgery. View Abstract
Engineered fetal cartilage: structural and functional analysis in vitro. View Abstract
The placenta as a cell source in fetal tissue engineering. View Abstract
Fetal tissue engineering: in utero tracheal augmentation in an ovine model. View Abstract
Positive intrapulmonary oncotic pressure enhances short-term lung growth acceleration after fetal tracheal occlusion. View Abstract
Ultrasound-guided fetal tracheal occlusion. View Abstract
The amniotic fluid as a source of cells for fetal tissue engineering. View Abstract
Continuous intrapulmonary distension with perfluorocarbon accelerates lung growth in infants with congenital diaphragmatic hernia: initial experience. View Abstract
Fetal tissue engineering: diaphragmatic replacement. View Abstract
The littlest patient. View Abstract
Prolonged local myometrial blockade prevents preterm labor after fetal surgery in a leporine model. View Abstract
Fetal response to neutral gas and liquid media for intraamniotic distension. View Abstract
Fetal carotid blood flow during videofetoscopy. View Abstract
Insulin-like growth factor-I gene expression in three models of accelerated lung growth. View Abstract
Continuous intrapulmonary distension with perfluorocarbon accelerates neonatal (but not adult) lung growth. View Abstract
Videofetoscopically assisted fetal tissue engineering: skin replacement. View Abstract
Videofetoscopically assisted fetal tissue engineering: bladder augmentation. View Abstract
Management of biliary atresia in the liver transplantation era: a 15-year, single-center experience. View Abstract
ECMO in evolution: the impact of changing patient demographics and alternative therapies on ECMO. View Abstract
Resection of a massive sacrococcygeal teratoma using hypothermic hypoperfusion: a novel use of extracorporeal membrane oxygenation. View Abstract
Fate of the reconstructed carotid artery after extracorporeal membrane oxygenation. View Abstract
Experimental fetal tracheal ligation and congenital diaphragmatic hernia: a pulmonary vascular morphometric analysis. View Abstract
Congenital diaphragmatic hernia and associated anomalies: their incidence, identification, and impact on prognosis. View Abstract
Surgically produced congenital diaphragmatic hernia in fetal rabbits. View Abstract
Antenatal diagnosis of isolated congenital diaphragmatic hernia is not an indicator of outcome. View Abstract
Experimental fetal tracheal ligation reverses the structural and physiological effects of pulmonary hypoplasia in congenital diaphragmatic hernia. View Abstract
[Liver transplantation in children: initial experience of the Instituto da Criança of the Hospital das Clínicas of Universidade de São Paulo]. View Abstract
[Acute abdomen in childhood caused by intestinal angiostrongylus infection: a case report]. View Abstract
[A new cannula for tracheostomy]. View Abstract
[Prevention of tracheo-innominate fistula following tracheostomy: anatomic relations of the trachea and brachiocephalic trunk]. View Abstract
Locations