Gregory Priebe, MD
Senior Associate, Critical Care Medicine; Senior Associate Physician, Division of Infectious Diseases
Associate Professor of Anaesthesia, Harvard Medical School
Image
Gregory Priebe, MD
Senior Associate, Critical Care Medicine; Senior Associate Physician, Division of Infectious Diseases
Associate Professor of Anaesthesia, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
Harvard Medical School
Boston
MA
Internship
Pediatrics
Boston Children's Hospital
Boston
MA
Residency
Chief Medical Resident
Boston Children's Hospital
Boston
MA
Fellowship
Pediatric Critical Care Medicine
Boston Children's Hospital
Boston
MA
Fellowship
Pediatric Infectious Disease
Boston Children's Hospital
Boston
MA
Fellowship
Research, Microbiology, Immunology
Brigham and Women’s Hospital
Boston
MA
Certifications
American Board of Pediatrics (Critical Care Medicine)
American Board of Pediatrics (Infectious Diseases)
Publications
Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock. View Abstract
Plasma Microbial Cell-Free DNA Metagenomic Next-Generation Sequencing in People With Cystic Fibrosis. View Abstract
Risk factors for central line-associated bloodstream infection in the pediatric intensive care setting despite standard prevention measures. View Abstract
De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen. View Abstract
Cystic Fibrosis Mice Are Highly Susceptible to Repeated Acute Pseudomonas aeruginosa Pneumonia after Intranasal Inoculation. View Abstract
Stress Ulcer Prophylaxis Versus Placebo-A Blinded Pilot Randomized Controlled Trial to Evaluate the Safety of Two Strategies in Critically Ill Infants With Congenital Heart Disease. View Abstract
Small-molecule activators of a bacterial signaling pathway inhibit virulence. View Abstract
Pediatric Ventilator-Associated Events Before and After a Multicenter Quality Improvement Initiative. View Abstract
Bundled Care to Reduce Sepsis Mortality: The Improving Pediatric Sepsis Outcomes (IPSO) Collaborative. View Abstract
Preventing pediatric catheter-associated urinary tract infections utilizing urinary catheter Kamishibai cards (K-cards). View Abstract
Multicomponent Pseudomonas aeruginosa Vaccines Eliciting Th17 Cells and Functional Antibody Responses Confer Enhanced Protection against Experimental Acute Pneumonia in Mice. View Abstract
An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. View Abstract
Association of Diagnostic Stewardship for Blood Cultures in Critically Ill Children With Culture Rates, Antibiotic Use, and Patient Outcomes: Results of the Bright STAR Collaborative. View Abstract
Optimizing surveillance for pediatric ventilator-associated events-But are they preventable? View Abstract
Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update. View Abstract
Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. View Abstract
Evolution towards Virulence in a Burkholderia Two-Component System. View Abstract
A Pseudomonas aeruginosa-Derived Particulate Vaccine Protects against P. aeruginosa Infection. View Abstract
Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung. View Abstract
Risk factors for pediatric surgical site infection following neurosurgical procedures for hydrocephalus: a retrospective single-center cohort study. View Abstract
Stewardship Intervention to Optimize Central Venous Catheter Utilization in Critically Ill Children. View Abstract
The Role of Anesthetic Management in Surgical Site Infections After Pediatric Intestinal Surgery. View Abstract
Stress ulcer prophylaxis versus placebo-a blinded randomized control trial to evaluate the safety of two strategies in critically ill infants with congenital heart disease (SUPPRESS-CHD). View Abstract
Central venous catheter bundle adherence: Kamishibai card (K-card) rounding for central-line-associated bloodstream infection (CLABSI) prevention. View Abstract
Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients. View Abstract
Multidisciplinary Quality Improvement Intervention to Achieve Sustained Improvement in Hand Hygiene Reliability in a Pediatric Intensive Care Unit. View Abstract
Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. View Abstract
Whole-Genome Sequences of Staphylococcus aureus Isolates from Cystic Fibrosis Lung Infections. View Abstract
Progress Toward the Elusive Pseudomonas aeruginosa Vaccine. View Abstract
Variability in antimicrobial use in pediatric ventilator-associated events. View Abstract
PLGA-encapsulation of the Pseudomonas aeruginosa PopB vaccine antigen improves Th17 responses and confers protection against experimental acute pneumonia. View Abstract
Construction of a Protective Vaccine Against Lipopolysaccharide-Heterologous Pseudomonas aeruginosa Strains Based on Expression Profiling of Outer Membrane Proteins During Infection. View Abstract
A putative lateral flagella of the cystic fibrosis pathogen Burkholderia dolosa regulates swimming motility and host cytokine production. View Abstract
Ceftaroline pharmacokinetics and pharmacodynamics in patients with cystic fibrosis. View Abstract
Factors Associated With Pediatric Ventilator-Associated Conditions in Six U.S. Hospitals: A Nested Case-Control Study. View Abstract
Incident Stenotrophomonas maltophilia infection and lung function decline in cystic fibrosis. View Abstract
Immune Recognition of the Epidemic Cystic Fibrosis Pathogen Burkholderia dolosa. View Abstract
From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. View Abstract
Global and local selection acting on the pathogen Stenotrophomonas maltophilia in the human lung. View Abstract
An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity. View Abstract
A Pediatric Approach to Ventilator-Associated Events Surveillance. View Abstract
Efficacy of Antibody to PNAG Against Keratitis Caused by Fungal Pathogens. View Abstract
Enteral Nutrition and Acid-Suppressive Therapy in the PICU: Impact on the Risk of Ventilator-Associated Pneumonia. View Abstract
Ventilator-Associated Events in Neonates and Children--A New Paradigm. View Abstract
Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia. View Abstract
Impact of Mandatory Public Reporting of Central Line-Associated Bloodstream Infections on Blood Culture and Antibiotic Utilization in Pediatric and Neonatal Intensive Care Units. View Abstract
Strategies to prevent ventilator-associated pneumonia in acute care hospitals: 2014 update. View Abstract
Microbiota-driven immune cellular maturation is essential for antibody-mediated adaptive immunity to Staphylococcus aureus infection in the eye. View Abstract
Vaccines for Pseudomonas aeruginosa: a long and winding road. View Abstract
Genetic variation of a bacterial pathogen within individuals with cystic fibrosis provides a record of selective pressures. View Abstract
Trehalose biosynthesis promotes Pseudomonas aeruginosa pathogenicity in plants. View Abstract
Disinfection of needleless connectors with chlorhexidine-alcohol provides long-lasting residual disinfectant activity. View Abstract
Collaboration between macrophages and vaccine-induced CD4+ T cells confers protection against lethal Pseudomonas aeruginosa pneumonia during neutropenia. View Abstract
Hepoxilin A(3) facilitates neutrophilic breach of lipoxygenase-expressing airway epithelial barriers. View Abstract
Topical neutralization of interleukin-17 during experimental Pseudomonas aeruginosa corneal infection promotes bacterial clearance and reduces pathology. View Abstract
Th17-stimulating protein vaccines confer protection against Pseudomonas aeruginosa pneumonia. View Abstract
Targeting pan-resistant bacteria with antibodies to a broadly conserved surface polysaccharide expressed during infection. View Abstract
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. View Abstract
Mucosal vaccination with a multivalent, live-attenuated vaccine induces multifactorial immunity against Pseudomonas aeruginosa acute lung infection. View Abstract
Analysis of acquisition of Pseudomonas aeruginosa gastrointestinal mucosal colonization and horizontal transmission in a murine model. View Abstract
Caveolin-1 modifies the immunity to Pseudomonas aeruginosa. View Abstract
Inescapable need for neutrophils as mediators of cellular innate immunity to acute Pseudomonas aeruginosa pneumonia. View Abstract
IL-17 is a critical component of vaccine-induced protection against lung infection by lipopolysaccharide-heterologous strains of Pseudomonas aeruginosa. View Abstract
The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection. View Abstract
A live-attenuated Pseudomonas aeruginosa vaccine elicits outer membrane protein-specific active and passive protection against corneal infection. View Abstract
Sepsis in the immunocompromised child: the least studied with the most to gain. View Abstract
Virulence of Pseudomonas aeruginosa in a murine model of gastrointestinal colonization and dissemination in neutropenia. View Abstract
Human monoclonal antibodies to Pseudomonas aeruginosa alginate that protect against infection by both mucoid and nonmucoid strains. View Abstract
The galU Gene of Pseudomonas aeruginosa is required for corneal infection and efficient systemic spread following pneumonia but not for infection confined to the lung. View Abstract
Protection against fatal Pseudomonas aeruginosa pneumonia in mice after nasal immunization with a live, attenuated aroA deletion mutant. View Abstract
Vaccines for Pseudomonas aeruginosa View Abstract
Construction and characterization of a live, attenuated aroA deletion mutant of Pseudomonas aeruginosa as a candidate intranasal vaccine. View Abstract
High-frequency oscillatory ventilation in pediatric patients. View Abstract
The effect of human serum DNAases on the ability to detect antibiotic-killed Escherichia coli in blood by PCR. View Abstract
Acquisition of expression of the Pseudomonas aeruginosa ExoU cytotoxin leads to increased bacterial virulence in a murine model of acute pneumonia and systemic spread. View Abstract
Bacterial subretinal abscess: a case report and review of the literature. View Abstract
Continuous improvement learning for residents. View Abstract