Jaymin Upadhyay, PhD

Assistant Professor of Anaesthesia, Harvard Medical School

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Jaymin Upadhyay, PhD

Assistant Professor of Anaesthesia, Harvard Medical School

Medical Services

Languages

Gujarati

Spanish

Education

Undergraduate School

West Virginia University

Morgantown

Graduate School

Boston University

Boston

Fellowship

McLean Hospital

Belmont

Publications

Reduced Cerebellar Volumes Associate with P300 Amplitude Attenuation in Children with Clinical High Risk for Psychosis and Early Onset Psychosis. View Abstract

Levacetylleucine (N-acetyl-l-leucine) for Niemann-Pick disease type C. View Abstract

The Impact of Childhood Maltreatment on Central Pain Processing in Individuals With Psychosis. View Abstract

Implications of the choroid plexus in Niemann-Pick disease Type C neuropathogenesis. View Abstract

Identifying Pain Subtypes in Patients With Craniofacial Lesions of Fibrous Dysplasia/McCune-Albright Syndrome. View Abstract

Current insights in ultra-rare adenylosuccinate synthetase 1 myopathy - meeting report on the First Clinical and Scientific Conference. 3 June 2024, National Centre for Advancing Translational Science, Rockville, Maryland, the United States of America. View Abstract

Characterization of pain and somatization and its relationship with psychopathology in early onset psychosis. View Abstract

Focused Ultrasound-Mediated Disruption of the Blood-Brain Barrier for AAV9 Delivery in a Mouse Model of Huntington's Disease. View Abstract

Phenotyping Pain in Patients With Fibrous Dysplasia/McCune-Albright Syndrome. View Abstract

Implications of Inflammatory Processes on a Developing Central Nervous System in Childhood-Onset Systemic Lupus Erythematosus. View Abstract

Characterization of central manifestations in patients with Niemann-Pick disease type C. View Abstract

Peripheral Pain Captured Centrally: Altered Brain Morphology on MRI in Small Fiber Neuropathy Patients With and Without an SCN9A Gene Variant. View Abstract

Case report: Chronic pain in a pediatric patient with late-onset pompe disease. View Abstract

A pilot investigation of muscle integrity in patients with ADSSL1 myopathy using electrical impedance myography. View Abstract

Synthetic CT Assessment of Lesions in Children With Rare Musculoskeletal Diseases. View Abstract

The experience of living with Niemann-Pick type C: a patient and caregiver perspective. View Abstract

Pharmacological Interventions Targeting Pain in Fibrous Dysplasia/McCune-Albright Syndrome. View Abstract

Diminished muscle integrity in patients with fibrodysplasia ossificans progressiva assessed with at-home electrical impedance myography. View Abstract

Continuing the conversation around opioid use disorder and post-traumatic stress disorder comorbidity. View Abstract

Case Report: The Imperfect Association Between Craniofacial Lesion Burden and Pain in Fibrous Dysplasia. View Abstract

Case Report: A Neuro-Ophthalmological Assessment of Vision Loss in a Pediatric Case of McCune-Albright Syndrome. View Abstract

Childhood maltreatment and its role in the development of pain and psychopathology. View Abstract

Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. View Abstract

Targeting neurological abnormalities in lysosomal storage diseases. View Abstract

Neurocircuitry basis of the opioid use disorder-post-traumatic stress disorder comorbid state: conceptual analyses using a dimensional framework. View Abstract

A multidisciplinary assessment of pain in juvenile idiopathic arthritis. View Abstract

Pain Phenotypes in Rare Musculoskeletal and Neuromuscular Diseases. View Abstract

Suppressed prefrontal cortex oscillations associate with clinical pain in fibrodysplasia ossificans progressiva. View Abstract

Altered Brain Network Connectivity Underlies Persistent Post-Traumatic Headache following Mild Traumatic Brain Injury in Youth. View Abstract

Mechanisms Underlying Unconscious Processing and Their Alterations in Post-traumatic Stress Disorder: Neuroimaging of Zero Monetary Outcomes Contextually Framed as "No Losses" vs. "No Gains". View Abstract

Implications of the putamen in pain and motor deficits in complex regional pain syndrome. View Abstract

Enhancing Choice and Outcomes for Therapeutic Trials in Chronic Pain: N-of-1 + Imaging (+ i). View Abstract

Delineating conditions and subtypes in chronic pain using neuroimaging. View Abstract

Longitudinal Evaluation of Pain, Flare-Up, and Emotional Health in Fibrodysplasia Ossificans Progressiva: Analyses of the International FOP Registry. View Abstract

Reward and aversion processing in patients with post-traumatic stress disorder: functional neuroimaging with visual and thermal stimuli. View Abstract

The role of fMRI in drug development. View Abstract

The Expansion of Heterotopic Bone in Fibrodysplasia Ossificans Progressiva Is Activin A-Dependent. View Abstract

A critical evaluation of validity and utility of translational imaging in pain and analgesia: Utilizing functional imaging to enhance the process. View Abstract

Detection of central circuits implicated in the formation of novel pain memories. View Abstract

Test-retest reliability of evoked heat stimulation BOLD fMRI. View Abstract

Multimodal assessment of nervous and immune system responses following sciatic nerve injury. View Abstract

Parallel buprenorphine phMRI responses in conscious rodents and healthy human subjects. View Abstract

Pain facilitation brain regions activated by nalbuphine are revealed by pharmacological fMRI. View Abstract

Pharmacological modulation of brain activity in a preclinical model of osteoarthritis. View Abstract

Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain. View Abstract

Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine. View Abstract

Default-mode-like network activation in awake rodents. View Abstract

Imaging drugs with and without clinical analgesic efficacy. View Abstract

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements. View Abstract

A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices. View Abstract

Direct optic nerve pulvinar connections defined by diffusion MR tractography in humans: implications for photophobia. View Abstract

Awake rat pharmacological magnetic resonance imaging as a translational pharmacodynamic biomarker: metabotropic glutamate 2/3 agonist modulation of ketamine-induced blood oxygenation level dependence signals. View Abstract

Alterations in brain structure and functional connectivity in prescription opioid-dependent patients. View Abstract

Robust, unbiased general linear model estimation of phMRI signal amplitude in the presence of variation in the temporal response profile. View Abstract

Evaluation of novel drugs using fMRI in early-phase clinical trials: safety monitoring. View Abstract

A key role of the basal ganglia in pain and analgesia--insights gained through human functional imaging. View Abstract

A fMRI evaluation of lamotrigine for the treatment of trigeminal neuropathic pain: pilot study. View Abstract

Improved characterization of BOLD responses for evoked sensory stimuli. View Abstract

Noninvasive mapping of human trigeminal brainstem pathways. View Abstract

A 'BOLD' experiment in defining the utility of fMRI in drug development. View Abstract

Effective and structural connectivity in the human auditory cortex. View Abstract

Diffusion properties of NAA in human corpus callosum as studied with diffusion tensor spectroscopy. View Abstract

Diffusion tensor spectroscopy and imaging of the arcuate fasciculus. View Abstract

Function and connectivity in human primary auditory cortex: a combined fMRI and DTI study at 3 Tesla. View Abstract