Jurriaan Peters, MD, PhD
Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School
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Jurriaan Peters, MD, PhD
Neurologist, Department of Neurology
Associate Professor of Neurology, Harvard Medical School
Medical Services
Languages
Dutch
English
Education
Medical School
Faculty of Medicine, Catholic University of Leuven
2002
Leuven
Belgium
Residency
Adult Neurology
VU University Medical Center Amsterdam
2003
Amsterdam
Netherlands
Residency
Adult Neurology
Haga Teaching Hospital
2006
Houten
Netherlands
Fellowship
Epilepsy & Clinical Neurophysiology
Boston Children's Hospital
2007
Boston
MA
Residency
Child Neurology
Boston Children's Hospital
2010
Boston
MA
Internship
Pediatrics
Boston Combined Residency Program (BCRP)
2011
Boston
MA
Fellowship
Neuroimaging at Neurology (ABPN Neuroscience Track)
Boston Children's Hospital
2012
Boston
MA
Certifications
American Board of Psychiatry and Neurology (Child and Adolescent Neurology)
American Board of Psychiatry and Neurology (Epilepsy)
Professional History
Jurriaan M. Peters MD, PhD, is an Associate Professor of Neurology at Harvard Medical School, and is a pediatric epileptologist with additional expertise in clinical neurophysiology and neuroimaging. He earned his MD at the Catholic University of Leuven, Belgium, and his PhD at the University of Utrecht. He did his Child Neurology training and Clinical Neurophysiology fellowship training at Boston Children’s Hospital.
Throughout his career he has operated on the boundary between clinical care and cutting edge novel technologies. He is the principal epileptologist at the Multidisciplinary Tuberous Sclerosis Clinic at Boston Children’s Hospital. His research in the Laboratory of Translational Neuroimaging and in the Computational Radiology Laboratory focuses on novel MRI and EEG modeling techniques in the localization of the seizure onset zone in children with medically refractory epilepsy, on how focal lesions give rise to a generalized epileptic encephalopathy; and on early medical and surgical treatment of epilepsy to mitigate detrimental effects on neurodevelopment.
Approach to Care
It is amazing that science can be applied to humans, so it is less abstract than mathematics or physics. But it is exactly the clinical application of novel technologies and innovations that can drive patient care forward and change the field.
Clinically, I am amazed by how hard work and a sustained effort in care can make a difference, not on a group level, but for individual patients. I believe strongly in “putting up a good fight”, as it often pays off. In that, I find that forming a diagnostic and therapeutic alliance with parents, and if needed with colleagues, can really positively impact the lives of patients and their families.
Clinically, I am amazed by how hard work and a sustained effort in care can make a difference, not on a group level, but for individual patients. I believe strongly in “putting up a good fight”, as it often pays off. In that, I find that forming a diagnostic and therapeutic alliance with parents, and if needed with colleagues, can really positively impact the lives of patients and their families.
Publications
Exploring proposed recommendations for immediate-use seizure medication: Treating both cluster and prolonged seizures with diazepam nasal spray. View Abstract
Prevalence, Characteristics, and Management of Pancreatic Tumors Among Children With Tuberous Sclerosis Complex. View Abstract
Accumulated seizure burden predicts neurodevelopmental outcome at 36?months of age in patients with tuberous sclerosis complex. View Abstract
Association of earlier surgery with improved postoperative language development in children with tuberous sclerosis complex. View Abstract
Drug-Resistant Epilepsy in Tuberous Sclerosis Complex Is Associated With TSC2 Genotype: More Findings From the Preventing Epilepsy Using Vigatrin (PREVeNT) Trial. View Abstract
Short-Term Impact of Seizures and Mitigation Opportunities. View Abstract
Publisher Correction to: Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. View Abstract
Taking a Newer, Faster, Intranasal Route: A Narrative Review of Transitioning to a Less-Invasive Rescue Treatment for Seizure Clusters. View Abstract
Analyses of patients who self-administered diazepam nasal spray for acute treatment of seizure clusters. View Abstract
Comment on: Failure to use new breakthrough treatments for epilepsy. View Abstract
Mapping Lesion-Related Epilepsy to a Human Brain Network. View Abstract
Early Treatment with Vigabatrin Does Not Decrease Focal Seizures or Improve Cognition in Tuberous Sclerosis Complex: The PREVeNT Trial. View Abstract
Acute seizure therapies in people with epilepsy: Fact or fiction? A U.S. Perspective. View Abstract
Morphological Features of Language Regions in Individuals with Tuberous Sclerosis Complex. View Abstract
Concomitant cannabidiol does not impact safety and effectiveness of diazepam nasal spray for seizure clusters: Post hoc analysis of a phase 3 safety study. View Abstract
Focal epilepsies: Update on diagnosis and classification. View Abstract
Treatment-Resistant Epilepsy and Tuberous Sclerosis Complex: Treatment, Maintenance, and Future Directions. View Abstract
Aluminum Thin Film Nanostructure Traces in Pediatric EEG Net for MRI and CT Artifact Reduction. View Abstract
Epilepsy Severity Is Associated With Head Circumference and Growth Rate in Infants With Tuberous Sclerosis Complex. View Abstract
The nose has it: Opportunities and challenges for intranasal drug administration for neurologic conditions including seizure clusters. View Abstract
Tubers Affecting the Fusiform Face Area Are Associated with Autism Diagnosis. View Abstract
Significant improvements in SEIzure interVAL (time between seizure clusters) across time in patients treated with diazepam nasal spray as intermittent rescue therapy for seizure clusters. View Abstract
Limited utility of structural MRI to identify the epileptogenic zone in young children with tuberous sclerosis. View Abstract
Reply to "Added value of high-resolution electrical source imaging of ictal activity in children with structural focal epilepsy". View Abstract
Virtual implantation using conventional scalp EEG delineates seizure onset and predicts surgical outcome in children with epilepsy. View Abstract
Comment on "Intranasal midazolam versus intravenous/rectal benzodiazepines for acute seizure control in children: A systematic review and meta-analysis". View Abstract
Infantile Hemiconvulsion-Hemiplegia and Epilepsy (IHHE) in a boy with tuberous sclerosis complex. View Abstract
Startle Epilepsy Triggered By Maternal Cough. View Abstract
Convolutional neural networks to identify malformations of cortical development: A feasibility study. View Abstract
Source imaging of seizure onset predicts surgical outcome in pediatric epilepsy. View Abstract
High-Density EEG in Current Clinical Practice and Opportunities for the Future. View Abstract
Tuber Locations Associated with Infantile Spasms Map to a Common Brain Network. View Abstract
Hippocampal Involvement With Vigabatrin-Related MRI Signal Abnormalities in Patients With Infantile Spasms: A Novel Finding. View Abstract
Patient-Specific Sensor Registration for Electrical Source Imaging Using a Deformable Head Model. View Abstract
LEARNING TO DETECT BRAIN LESIONS FROM NOISY ANNOTATIONS. View Abstract
A structural brain network of genetic vulnerability to psychiatric illness. View Abstract
Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex. View Abstract
The Connectivity Fingerprint of the Fusiform Gyrus Captures the Risk of Developing Autism in Infants with Tuberous Sclerosis Complex. View Abstract
Pilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex. View Abstract
EEG Spectral Features in Sleep of Autism Spectrum Disorders in Children with Tuberous Sclerosis Complex. View Abstract
Update on Drug Management of Refractory Epilepsy in Tuberous Sclerosis Complex. View Abstract
Clinical Reasoning: A 6-week-old infant with migrating focal seizures. View Abstract
Lesion-Constrained Electrical Source Imaging: A Novel Approach in Epilepsy Surgery for Tuberous Sclerosis Complex. View Abstract
Early white matter development is abnormal in tuberous sclerosis complex patients who develop autism spectrum disorder. View Abstract
Scalp EEG spikes predict impending epilepsy in TSC infants: A longitudinal observational study. View Abstract
Reproducibility of Structural and Diffusion Tensor Imaging in the TACERN Multi-Center Study. View Abstract
Resting-State fMRI Networks in Children with Tuberous Sclerosis Complex. View Abstract
Increased electroencephalography connectivity precedes epileptic spasm onset in infants with tuberous sclerosis complex. View Abstract
The Evolution of Subclinical Seizures in Children With Tuberous Sclerosis Complex. View Abstract
White matter mean diffusivity correlates with myelination in tuberous sclerosis complex. View Abstract
Seizure Prediction Models in the Neonatal Intensive Care Unit. View Abstract
Recurrent SLC1A2 variants cause epilepsy via a dominant negative mechanism. View Abstract
Multi-Resolution Graph Based Volumetric Cortical Basis Functions From Local Anatomic Features. View Abstract
Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy. View Abstract
Longitudinal Effects of Everolimus on White Matter Diffusion in Tuberous Sclerosis Complex. View Abstract
High vigabatrin dosage is associated with lower risk of infantile spasms relapse among children with tuberous sclerosis complex. View Abstract
Corpus Callosum White Matter Diffusivity Reflects Cumulative Neurological Comorbidity in Tuberous Sclerosis Complex. View Abstract
Surgical resection of ripple onset predicts outcome in pediatric epilepsy. View Abstract
A Comparison of Point and Complete Electrode Models in a Finite Difference Model of Invasive Electrode Measurements. View Abstract
Presurgical language fMRI: Technical practices in epilepsy surgical planning. View Abstract
Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy. View Abstract
Vigabatrin for Epileptic Spasms and Tonic Seizures in Tuberous Sclerosis Complex. View Abstract
Detailed Magnetic Resonance Imaging (MRI) Analysis in Infantile Spasms. View Abstract
Presurgical language fMRI: Clinical practices and patient outcomes in epilepsy surgical planning. View Abstract
Response to clobazam in continuous spike-wave during sleep. View Abstract
Presentation and Diagnosis of Tuberous Sclerosis Complex in Infants. View Abstract
Localization of stereo-electroencephalography signals using a finite difference complete electrode model. View Abstract
Systemic Manifestations in Pyridox(am)ine 5'-Phosphate Oxidase Deficiency. View Abstract
Reduced thalamic volume in patients with Electrical Status Epilepticus in Sleep. View Abstract
Dynamic Electrical Source Imaging (DESI) of Seizures and Interictal Epileptic Discharges Without Ensemble Averaging. View Abstract
Extensions to a manifold learning framework for time-series analysis on dynamic manifolds in bioelectric signals. View Abstract
A pediatric epilepsy diagnostic tool for use in resource-limited settings: A pilot study. View Abstract
SCN2A-Related Early-Onset Epileptic Encephalopathy Responsive to Phenobarbital. View Abstract
Improved fidelity of brain microstructure mapping from single-shell diffusion MRI. View Abstract
Tubers are neither static nor discrete: Evidence from serial diffusion tensor imaging. View Abstract
Clinical Electroencephalographic Biomarker for Impending Epilepsy in Asymptomatic Tuberous Sclerosis Complex Infants. View Abstract
Tuberous Sclerosis: A New Frontier in Targeted Treatment of Autism. View Abstract
Teaching video neuroimages: nonepileptic myoclonus in a neonate following severe hypoxic-ischemic injury. View Abstract
Altered Structural Brain Networks in Tuberous Sclerosis Complex. View Abstract
Localization of sleep spindles, k-complexes, and vertex waves with subdural electrodes in children. View Abstract
Safety and retention rate of rufinamide in 300 patients: a single pediatric epilepsy center experience. View Abstract
Treatment for continuous spikes and waves during sleep (CSWS): survey on treatment choices in North America. View Abstract
Clobazam: effect on frequency of seizures and safety profile in different subgroups of children with epilepsy. View Abstract
A fully Bayesian inference framework for population studies of the brain microstructure. View Abstract
Insult to injury: transient encephalopathy in a brain-injured adolescent. View Abstract
Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. View Abstract
A mathematical framework for the registration and analysis of multi-fascicle models for population studies of the brain microstructure. View Abstract
Long-term response to high-dose diazepam treatment in continuous spikes and waves during sleep. View Abstract
Diffusion tensor imaging and related techniques in tuberous sclerosis complex: review and future directions. View Abstract
Continuous Spikes and Waves during Sleep: Electroclinical Presentation and Suggestions for Management. View Abstract
[The brain functional network of children with autism: redundancy and disconnection]. View Abstract
Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. View Abstract
Brain functional networks in syndromic and non-syndromic autism: a graph theoretical study of EEG connectivity. View Abstract
A magnetic resonance imaging study of cerebellar volume in tuberous sclerosis complex. View Abstract
Automated quantification of spikes. View Abstract
Whole Brain Group Network Analysis Using Network Bias and Variance Parameters View Abstract
Electrical status epilepticus in sleep: clinical presentation and pathophysiology. View Abstract
The tower of Babel: survey on concepts and terminology in electrical status epilepticus in sleep and continuous spikes and waves during sleep in North America. View Abstract
Impaired language pathways in tuberous sclerosis complex patients with autism spectrum disorders. View Abstract
Clinical staging and electroencephalographic evolution of continuous spikes and waves during sleep. View Abstract
Short-term response of sleep-potentiated spiking to high-dose diazepam in electric status epilepticus during sleep. View Abstract
WHOLE BRAIN GROUP NETWORK ANALYSIS USING NETWORK BIAS AND VARIANCE PARAMETERS. View Abstract
Early thalamic lesions in patients with sleep-potentiated epileptiform activity. View Abstract
Patients with electrical status epilepticus in sleep share similar clinical features regardless of their focal or generalized sleep potentiation of epileptiform activity. View Abstract
Behavioral measures and EEG monitoring using the Brain Symmetry Index during the Wada test in children. View Abstract
Good outcome with early empiric treatment of neural larva migrans due to Baylisascaris procyonis. View Abstract
Loss of white matter microstructural integrity is associated with adverse neurological outcome in tuberous sclerosis complex. View Abstract
Registration and analysis of white matter group differences with a multi-fiber model. View Abstract
Spinal cord involvement in a child with raccoon roundworm (Baylisascaris procyonis) meningoencephalitis. View Abstract
Continuous spike and waves during sleep and electrical status epilepticus in sleep. View Abstract
Guillain-Barré syndrome in a child with pain: lessons learned from a late diagnosis. View Abstract
High-dose intravenous levetiracetam for acute seizure exacerbation in children with intractable epilepsy. View Abstract
Rapid resolution of diffusion weighted MRI abnormality in a patient with a stuttering stroke. View Abstract
Picture of the month--quiz case. Moyamoya disease. View Abstract
Intracranial penetration of a halo pin causing an epileptic seizure. View Abstract
Tijdschr Neurol Neurochir View Abstract
A brain symmetry index (BSI) for online EEG monitoring in carotid endarterectomy. View Abstract
Event-related correlations in learning impaired children during A hybrid go/no-go choice reaction visual-motor task. View Abstract
Tijdschr Neurol Neurochir View Abstract
Population study of benign rolandic epilepsy: is treatment needed? View Abstract
Locations