Margaret Chang, MD, PhD
Rheumatologist, Rheumatology Program
Assistant Professor of Pediatrics, Harvard Medical School
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Margaret Chang, MD, PhD
Rheumatologist, Rheumatology Program
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
David Geffen School of Medicine at UCLA
2013
Los Angeles
CA
Internship
Boston Children's Hospital
2014
Boston
MA
Residency
Boston Children's Hospital
2016
Boston
MA
Fellowship
Boston Children's Hospital
2019
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Rheumatology)
Publications
Sex Differences in B Cells From the Joints of Children With Oligoarticular Juvenile Idiopathic Arthritis. View Abstract
Implementation study of the CARRA Uveitis Consensus Treatment Plans: feasibility for clinical practice and applicability for research. View Abstract
Severe Features of Systemic Juvenile Idiopathic Arthritis in Patients With Congenital Heart Disease. View Abstract
Joint-specific memory, resident memory T cells and the rolling window of opportunity in arthritis. View Abstract
Elevation of IL-17 Cytokines Distinguishes Kawasaki Disease From Other Pediatric Inflammatory Disorders. View Abstract
Type I interferon signature and cycling lymphocytes in macrophage activation syndrome. View Abstract
Development of a Screening Algorithm for Lung Disease in Systemic Juvenile Idiopathic Arthritis. View Abstract
Incidence and Risk Factors for Eosinophilia and Lung Disease in Biologic-Exposed Children With Systemic Juvenile Idiopathic Arthritis. View Abstract
Disordered T cell-B cell interactions in autoantibody-positive inflammatory arthritis. View Abstract
mTORC1 links pathology in experimental models of Still's disease and macrophage activation syndrome. View Abstract
Joint-Specific Memory and Sustained Risk for New Joint Accumulation in Autoimmune Arthritis. View Abstract
An Evidence-Based Guideline Improves Outcomes for Patients With Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome. View Abstract
Proteomics based markers of clinical pain severity in juvenile idiopathic arthritis. View Abstract
Weekly Adalimumab, an Effective Alternative for Refractory Uveitis in Children. View Abstract
Arthritis flares mediated by tissue-resident memory T cells in the joint. View Abstract
Th1 polarization defines the synovial fluid T cell compartment in oligoarticular juvenile idiopathic arthritis. View Abstract
IL-1ß-driven osteoclastogenic Tregs accelerate bone erosion in arthritis. View Abstract
Uveitis in Children and Adolescents. View Abstract
A multidisciplinary assessment of pain in juvenile idiopathic arthritis. View Abstract
Cyclophosphamide use in treatment of refractory Kawasaki disease with coronary artery aneurysms. View Abstract
Distinct clinical and immunological features of SARS-CoV-2-induced multisystem inflammatory syndrome in children. View Abstract
Identification of Prevotella Oralis as a possible target antigen in children with Enthesitis related arthritis. View Abstract
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis. View Abstract
Adenosine deaminase 2 as a biomarker of macrophage activation syndrome in systemic juvenile idiopathic arthritis. View Abstract
Antibody-dependent and -independent mechanisms of inflammatory arthritis. View Abstract
Calm in the midst of cytokine storm: a collaborative approach to the diagnosis and treatment of hemophagocytic lymphohistiocytosis and macrophage activation syndrome. View Abstract
Megakaryocytes compensate for Kit insufficiency in murine arthritis. View Abstract
Galectin-1 regulates tissue exit of specific dendritic cell populations. View Abstract
Glucose metabolism is required for oxidized LDL-induced macrophage survival: role of PI3K and Bcl-2 family proteins. View Abstract
Galectin-1 co-clusters CD43/CD45 on dendritic cells and induces cell activation and migration through Syk and protein kinase C signaling. View Abstract
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation. View Abstract
Phosphatidylinostitol-3 kinase and phospholipase C enhance CSF-1-dependent macrophage survival by controlling glucose uptake. View Abstract
beta-Adrenoreceptors reactivate Kaposi's sarcoma-associated herpesvirus lytic replication via PKA-dependent control of viral RTA. View Abstract