Monica E. Kleinman, MD

Chief Safety Officer, Program for Patient Safety and Quality; Co-Chair, Resuscitation Quality Program
Associate Professor of Anesthesia (Pediatrics), Harvard Medical School
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 Monica Kleinman, MD

Monica E. Kleinman, MD

Chief Safety Officer, Program for Patient Safety and Quality; Co-Chair, Resuscitation Quality Program
Associate Professor of Anesthesia (Pediatrics), Harvard Medical School

Medical Services

Languages
English
Education
Medical School
Brown University Program in Medicine
1987
Providence
RI
Internship
Rhode Island Hospital
1988
Providence
RI
Residency
Chief Resident
Rhode Island Hospital
1990
Providence
RI
Fellowship
Pediatric Critical Care
Yale-New Haven Hospital
1994
New Haven
CT
Certifications
American Board of Pediatrics (Critical Care Medicine)

Publications

Early Sodium Bicarbonate Use in Pediatric In-Hospital Cardiac Arrest: A Single-Center, Retrospective Cohort Study, 2013-2023. View Abstract
Personal Public Disclosure: A New Paradigm for Meeting Regulatory Requirements Under Exception From Informed Consent. View Abstract
Longitudinal Changes in Myocardial Deformation in Hutchinson-Gilford Progeria Syndrome. View Abstract
Why physicians use sodium bicarbonate during cardiac arrest: A cross-sectional survey study of adult and pediatric clinicians. View Abstract
2024 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
2024 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
Anesthetic Management of Cardiopulmonary Bypass in Hutchinson-Gilford Progeria Syndrome: A Case Report. View Abstract
Willingness to participate in an active exception from informed consent trial in the pediatric intensive care unit. View Abstract
Characteristics of Pediatric In-Hospital Cardiac Arrests and Resuscitation Duration. View Abstract
Corrigendum to "2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces" [Resuscitation 195 (2024) 109992]. View Abstract
Handle with care: Preventing harm during critical care unit relocation. View Abstract
Intervention for critical aortic stenosis in Hutchinson-Gilford progeria syndrome. View Abstract
Recommendations for the Management of Initial and Refractory Pediatric Status Dystonicus. View Abstract
Association Between Chest Compression Pause Duration and Survival After Pediatric In-Hospital Cardiac Arrest. View Abstract
Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome. View Abstract
Prevention of postoperative stroke in pediatric moyamoya patients: a standardized perioperative care protocol. View Abstract
2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
2023 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
How do we detect and respond to clinical deterioration in hospitalized children? Results of the Pediatric Care BefOre Deterioration Events (CODE) survey. View Abstract
Can an individual be enrolled in more than one clinical trial using exception from informed consent? View Abstract
Progression of Cardiac Abnormalities in Hutchinson-Gilford Progeria Syndrome: A Prospective Longitudinal Study. View Abstract
Deep brain stimulation for medically refractory status dystonicus in UBA5-related disorder. View Abstract
Calcium during cardiac arrest: A systematic review. View Abstract
Plasma Progerin in Patients With Hutchinson-Gilford Progeria Syndrome: Immunoassay Development and Clinical Evaluation. View Abstract
2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
Community consultation in the pediatric intensive care unit for an exception from informed consent Trial: A survey of patient caregivers. View Abstract
Baseline Range of Motion, Strength, Motor Function, and Participation in Youth with Hutchinson-Gilford Progeria Syndrome. View Abstract
Characteristics and Outcomes of Cardiac Arrest in Adult Patients Admitted to Pediatric Services: A Descriptive Analysis of the American Heart Association's Get With The Guidelines-Resuscitation Data. View Abstract
2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
2022 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
Guidance for Cardiopulmonary Resuscitation of Children With Suspected or Confirmed COVID-19. View Abstract
Calcium Administration During Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest in Children With Heart Disease Is Associated With Worse Survival-A Report From the American Heart Association's Get With The Guidelines-Resuscitation (GWTG-R) Registry. View Abstract
Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. View Abstract
In-Hospital Cardiac Arrest in Adult Patients Admitted to a Quaternary Children's Center. View Abstract
Emergency Medical Response for Non-Hospitalized Person Events in a Children's Hospital. View Abstract
Emergency Medical Response for Non-Hospitalized Person Events in a Children's Hospital. View Abstract
A Multimodal Approach to Training Coronavirus Disease (COVID-19) Processes Across Four Intensive Care Units. View Abstract
2022 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19: From the Emergency Cardiovascular Care Committee and Get With The Guidelines-Resuscitation Adult and Pediatric Task Forces of the American Heart Association in Collaboration With the American Academy of Pediatrics, American Association for Respiratory Care, the Society of Critical Care Anesthesiologists, and American Society of Anesthesiologists. View Abstract
Peri-arrest bolus epinephrine practices amongst pediatric resuscitation experts. View Abstract
Weaning Dexmedetomidine in Non-ICU Areas: An Implementation Effort. View Abstract
Risk factors and outcomes for recurrent paediatric in-hospital cardiac arrest: Retrospective multicenter cohort study. View Abstract
2021 Interim Guidance to Health Care Providers for Basic and Advanced Cardiac Life Support in Adults, Children, and Neonates With Suspected or Confirmed COVID-19. View Abstract
Implementation of an Analgesia-Sedation Protocol Is Associated With Reduction in Midazolam Usage in the PICU. View Abstract
eSIMPLER: A Dynamic, Electronic Health Record-Integrated Checklist for Clinical Decision Support During PICU Daily Rounds. View Abstract
Acute Management of High-Risk and Intermediate-Risk Pulmonary Embolism in Children: A Review. View Abstract
Stewardship Intervention to Optimize Central Venous Catheter Utilization in Critically Ill Children. View Abstract
Family presence during resuscitation in paediatric and neonatal cardiac arrest: A systematic review. View Abstract
Pediatric timing of epinephrine doses: A systematic review. View Abstract
Trends over time in drug administration during pediatric in-hospital cardiac arrest in the United States. View Abstract
eStablish And Formalize Expert Criteria for Avoidable Resuscitation Review (SAFECARR) Electronic Delphi: Development of a Consensus Framework for Classifying and Reviewing Cardiac Arrests Within the PICU. View Abstract
Adult Advanced Life Support: International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
The Impact of Videolaryngoscopy on Endotracheal Intubation Success by a Pediatric/Neonatal Critical Care Transport Team. View Abstract
Interim Guidance for Basic and Advanced Life Support in Children and Neonates With Suspected or Confirmed COVID-19. View Abstract
Intravenous vs. intraosseous administration of drugs during cardiac arrest: A systematic review. View Abstract
Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study. View Abstract
Pediatric Massive and Submassive Pulmonary Embolism: A Single-Center Experience. View Abstract
2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces. View Abstract
2019 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Multidisciplinary Quality Improvement Intervention to Achieve Sustained Improvement in Hand Hygiene Reliability in a Pediatric Intensive Care Unit. View Abstract
A Stroke Alert Protocol Decreases the Time to Diagnosis of Brain Attack Symptoms in a Pediatric Emergency Department. View Abstract
Cardiopulmonary Resuscitation in the Pediatric Cardiac Catheterization Laboratory: A Report From the American Heart Association's Get With the Guidelines-Resuscitation Registry. View Abstract
Trends in Survival After Pediatric In-Hospital Cardiac Arrest in the United States. View Abstract
Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome. View Abstract
ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement. View Abstract
ILCOR Scientific Knowledge Gaps and Clinical Research Priorities for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care: A Consensus Statement. View Abstract
Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome. View Abstract
Cardiopulmonary Resuscitation in Infants and Children With Cardiac Disease: A Scientific Statement From the American Heart Association. View Abstract
Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome. View Abstract
Physiologic response to pre-arrest bolus dilute epinephrine in the pediatric intensive care unit. View Abstract
Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib. View Abstract
Out-of-Hospital Cardiac Arrest Resuscitation Systems of Care: A Scientific Statement From the American Heart Association. View Abstract
Extracorporeal Cardiopulmonary Resuscitation in Pediatric Cardiac Arrest: Same Principles, Different Practices. View Abstract
Pubertal Progression in Female Adolescents with Progeria. View Abstract
Predicting Unplanned Transfers to the Intensive Care Unit: A Machine Learning Approach Leveraging Diverse Clinical Elements. View Abstract
2017 American Heart Association Focused Update on Adult Basic Life Support and Cardiopulmonary Resuscitation Quality: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Validation of a pediatric early warning system for hospitalized pediatric oncology patients in a resource-limited setting. View Abstract
Ophthalmologic Features of Progeria. View Abstract
Improved outcomes after successful implementation of a pediatric early warning system (PEWS) in a resource-limited pediatric oncology hospital. View Abstract
2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures. View Abstract
2016 AHA/ACC Clinical Performance and Quality Measures for Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures. View Abstract
292: LOW SURVIVAL AFTER EXTRACORPOREAL CARDIOPULMONARY RESUSCITATION IN NONCARDIAC PATIENTS. View Abstract
1191: VALIDATION OF A PEDIATRIC EARLY WARNING SCORE IN A PEDIATRIC ONCOLOGY HOSPITAL IN GUATEMALA. View Abstract
Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome. View Abstract
The decision-making process and criteria in selecting candidate drugs for progeria clinical trials. View Abstract
International Pediatric Otolaryngology Group (IPOG) consensus recommendations: Routine peri-operative pediatric tracheotomy care. View Abstract
Validation of a Pediatric Early Warning Score in Hospitalized Pediatric Oncology and Hematopoietic Stem Cell Transplant Patients. View Abstract
Part 1: Executive Summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Part 5: Adult Basic Life Support and Cardiopulmonary Resuscitation Quality: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Part 6: Pediatric Basic Life Support and Pediatric Advanced Life Support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 6: Pediatric basic life support and pediatric advanced life support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
Part 6: Pediatric Basic Life Support and Pediatric Advanced Life Support: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations (Reprint). View Abstract
American Heart Association Response to the 2015 Institute of Medicine Report on Strategies to Improve Cardiac Arrest Survival. View Abstract
Parents' Experiences of Pediatric Palliative Transports: A Qualitative Case Series. View Abstract
Enhancing the power of simulation for complex clinical care. View Abstract
Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome. View Abstract
Assessment of hemoglobin threshold for packed RBC transfusion in a medical-surgical PICU. View Abstract
Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome. View Abstract
Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment. View Abstract
Cardiopulmonary resuscitation quality: [corrected] improving cardiac resuscitation outcomes both inside and outside the hospital: a consensus statement from the American Heart Association. View Abstract
Examining pediatric resuscitation education using simulation and scripted debriefing: a multicenter randomized trial. View Abstract
Early identification of children at risk for critical care: standardizing communication for inter-emergency department transfers. View Abstract
Pediatric CPR quality targets--not just for 'grown-ups'. View Abstract
Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome. View Abstract
A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome. View Abstract
Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome. View Abstract
Hutchinson-Gilford progeria is a skeletal dysplasia. View Abstract
Part 1: executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Part 14: pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 10: Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 3: Evidence evaluation process: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 4: Conflict of interest management before, during, and after the 2010 International Consensus Conference on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 7: CPR techniques and devices: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Conventional cardiopulmonary resuscitation by bystanders improved outcomes in children with out-of-hospital cardiac arrest. View Abstract
Pediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
Pediatric advanced life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. View Abstract
Risk factors for central line-associated bloodstream infection in pediatric intensive care units. View Abstract
Part 10: Paediatric basic and advanced life support: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. View Abstract
Part 7: CPR techniques and devices: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
Part 4: Conflict of interest management before, during, and after the 2010 International Consensus Conference on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
Part 3: Evidence evaluation process: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. View Abstract
The use of vasoactive agents via peripheral intravenous access during transport of critically III infants and children. View Abstract
Safety of surfactant administration before transport of premature infants. View Abstract
Regional systems of care for out-of-hospital cardiac arrest: A policy statement from the American Heart Association. View Abstract
Regionalization of critical care: not just for kids. View Abstract
Postoperative pulmonary embolism in a three year old with Klippel-Trenaunay syndrome. View Abstract
Postresuscitation care. View Abstract
A simulator-based tool that assesses pediatric resident resuscitation competency. View Abstract
New approaches to progeria. View Abstract
Toward a new paradigm in hospital-based pediatric education: the development of an onsite simulator program. View Abstract
Acute arsenic poisoning in two siblings. View Abstract
Clinical practice parameters for pediatric and neonatal septic shock: to have or to have not? View Abstract
Accuracy of a new low-flow sidestream capnography technology in newborns: a pilot study. View Abstract
Comparison of intravenous and endotracheal epinephrine during cardiopulmonary resuscitation in newborn piglets. View Abstract