Paul A. Rufo, MD, MMSc

Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
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Paul A. Rufo, MD, MMSc

Paul A. Rufo, MD, MMSc

Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
Education
Undergraduate School
Harvard University
1985
Cambridge
MA
Medical School
University of Massachusetts Medical School
1990
Worcester
MA
Internship
Johns Hopkins Hospital
1991
Baltimore
MD
Residency
Johns Hopkins Hospital
1993
Baltimore
MD
Fellowship
Pediatric Gastroenterology
Boston Children's Hospital
1994
Boston
MA
Fellowship
Cell Biology
Boston Children's Hospital
1996
Boston
MA
Fellowship
Pfizer Fellowship in Clinical Investigation
Beth Israel Deaconess Medical Center
2002
Boston
MA
Media
Caregiver Profile

Meet Dr. Paul Rufo

Certifications
American Board of Pediatrics (Gastroenterology)
Safe Zone Trained
Professional History

Assistant Professor of Pediatrics at HMS.  I also serve as Program Director for the HMS Fellowship in Pediatric Gastroenterology and Nutrition.

Publications

Clinical outcomes of maintenance therapy with sulfasalazine compared to 5-aminosalicylates in children with ulcerative colitis. View Abstract
Higher alpha diversity and Lactobacillus blooms are associated with better engraftment after fecal microbiota transplant in inflammatory bowel disease. View Abstract
Evaluation and novel treatment in a case of refractory small bowel-small bowel intussusception. View Abstract
Inpatient management of iron deficiency anemia in pediatric patients with inflammatory bowel disease: A single center experience. View Abstract
Analysis of missed clinic visits, preferred languages, and telemedicine in a pediatric gastroenterology practice. View Abstract
Efficacy and Safety of Tacrolimus or Infliximab Therapy in Children and Young Adults With Acute Severe Colitis. View Abstract
Advancing Health Equity and Inclusion in an Academic Pediatric Medical Center: Priorities Addressed and Lessons Learned. View Abstract
Higher alpha diversity and Lactobacillus blooms are associated with better engraftment after Fecal Microbiota Transplant in Inflammatory Bowel Disease. View Abstract
Efficacy and Safety of Sulfasalazine Suspension in Children With Ulcerative Colitis. View Abstract
The Specific Carbohydrate Diet: Obstacle and Opportunities. View Abstract
Efficacy and Safety of High-dose Cholecalciferol in Patients With Inflammatory Bowel Disease Receiving Infliximab. View Abstract
Stratification of risk of progression to colectomy in ulcerative colitis via measured and predicted gene expression. View Abstract
Analysis of Using the Total White Blood Cell Count to Define Severe New-onset Ulcerative Colitis in Children. View Abstract
Protein-Losing Enteropathy in the Setting of Iron Deficiency Anemia: A Case Series. View Abstract
Pediatric Collagenous Gastroenterocolitis Successfully Treated with Methotrexate. View Abstract
Screening and Counseling for Alcohol Use in Adolescents With Chronic Medical Conditions in the Ambulatory Setting. View Abstract
Clinical and biological predictors of response to standardised paediatric colitis therapy (PROTECT): a multicentre inception cohort study. View Abstract
Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response. View Abstract
Effectiveness of oral iron supplementation in treatment of anemia associated with pediatric ulcerative colitis flare. View Abstract
Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. View Abstract
Serologic Reactivity Reflects Clinical Expression of Ulcerative Colitis in Children. View Abstract
Commentary: Button Batteries in Fidget Spinners: Is It Time to Push the "Panic Button"? View Abstract
Enhanced Contribution of HLA in Pediatric Onset Ulcerative Colitis. View Abstract
Protein-Losing Enteropathy in the Setting of Severe Iron Deficiency Anemia. View Abstract
Histologic Correlates of Clinical and Endoscopic Severity in Children Newly Diagnosed With Ulcerative Colitis. View Abstract
The Role of Environmental Factors in the Pathogenesis of Inflammatory Bowel Diseases: A Review. View Abstract
A randomized controlled trial of levodopa in patients with Angelman syndrome. View Abstract
Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. View Abstract
Correlation of endoscopic disease severity with pediatric ulcerative colitis activity index score in children and young adults with ulcerative colitis. View Abstract
Assessment of Fecal ASCA Measurement as a Biomarker of Crohn Disease in Pediatric Patients. View Abstract
A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth. View Abstract
Health Care Maintenance in Adolescents with Inflammatory Bowel Disease. View Abstract
Electrophysiological Studies into the Safety of the Anti-diarrheal Drug Clotrimazole during Oral Rehydration Therapy. View Abstract
Inflammatory bowel disease and neoplasia in children. View Abstract
NASPGHAN guidelines for training in pediatric gastroenterology. View Abstract
Health supervision in the management of children and adolescents with IBD: NASPGHAN recommendations. View Abstract
Desquamative enteropathy and pyloric atresia without skin disease caused by a novel intracellular beta4 integrin mutation. View Abstract
Increased incidence of urinary matrix metalloproteinases as predictors of disease in pediatric patients with inflammatory bowel disease. View Abstract
Adalimumab for the treatment of Crohn-like colitis and enteritis in glycogen storage disease type Ib. View Abstract
Adalimumab for the treatment of Crohn-like colitis and enteritis in glycogen storage disease type Ib View Abstract
Challenges and progress in pediatric inflammatory bowel disease. View Abstract
Fecal lactoferrin is a sensitive and specific marker of disease activity in children and young adults with inflammatory bowel disease. View Abstract
Pancreatitis as the initial manifestation of stage IV neuroblastoma. View Abstract
Why good pouches go bad. View Abstract
Pancreatitis as the intitial manifestation of Stage IV Neuroblastoma - A Case Report View Abstract
Fecal ASCA Measurements in the Assessment of Pediatric Patients with Crohn’s Disease (CD) or Suspected Inflammatory Bowel Disease (IBD) View Abstract
Current Therapy of Inflammatory Bowel Disease in Children View Abstract
Current therapy of inflammatory bowel disease in children. View Abstract
Severe colitis in children. View Abstract
IBD in children: the more you look, the more you see.... View Abstract
Serial Fecal Lactoferrin Measurements are Useful in the Interval Assessment of Patients with Active and Inactive Inflammatory Bowel Disease View Abstract
Diarrhea – Pediatric View Abstract
The Detection of Lactoferrin, ASCA and ANCA in Feces is useful for Assessing Pediatric IBD Patients View Abstract
Anti-inflammatory Activities Displayed by Triphenyl and Imidazole Containing Compounds View Abstract
Diarrhea-associated HIV-1 APIs potentiate muscarinic activation of Cl- secretion by T84 cells via prolongation of cytosolic Ca2+ signaling. View Abstract
Fecal lactoferrin is a sensitive and specific marker in identifying intestinal inflammation. View Abstract
Enhancement of intracellular Ca Signaling and Chloride Transport by Nelfinavir and Other Aspartyl Protease inhibitors View Abstract
Pouchitis: Evolution of a New Form of Inflammatory Bowel Disease View Abstract
The antifungal antibiotic, clotrimazole, inhibits chloride secretion by human intestinal T84 cells via blockade of distinct basolateral K+ conductances. Demonstration of efficacy in intact rabbit colon and in an in vivo mouse model of cholera. View Abstract
Proteolytic activation of cholera toxin and Escherichia coli labile toxin by entry into host epithelial cells. Signal transduction by a protease-resistant toxin variant. View Abstract
Proteolytic Activation of cholera toxin by Eschericia coli labile toxin by entry into host epithelial cells: signal transduction by a proteolytic resistant toxin variant View Abstract
The antifungal antibiotic, clotrimazole, inhibits Cl- secretion by polarized monolayers of human colonic epithelial cells. View Abstract
Transcytosis of cholera toxin subunits across model human intestinal epithelia. View Abstract
Pulmonology View Abstract
How families cope with diabetes in adolescence. An approach and case analyses. View Abstract