Richard S. Lee, MD
Vice Chair, Clinical Affairs; Hilary and Geoffrey Grove Family Chair in Urology; Director, Oncology, Transplant, & Bladder Exstrophy; Pediatric Urologist, Department of Urology
Associate Professor of Surgery, Harvard Medical School
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Richard S. Lee, MD
Vice Chair, Clinical Affairs; Hilary and Geoffrey Grove Family Chair in Urology; Director, Oncology, Transplant, & Bladder Exstrophy; Pediatric Urologist, Department of Urology
Associate Professor of Surgery, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Princeton University
1998
Princeton
NJ
Medical School
Jefferson Medical College, Thomas Jefferson University
1998
Philadelphia
PA
Internship
Surgery
University of Washington
1999
Seattle
WA
Residency
Surgery
University of Washington
2000
Seattle
WA
Residency
Urology
University of Washington
2003
Seattle
WA
Residency
Chief Urology Resident
University of Washington
2004
Seattle
WA
Fellowship
Pediatric Urology
Boston Children's Hospital
2007
Boston
MA
Media
Caregiver Profile
Meet Dr. Richard Lee
Certifications
American Board of Urology (Pediatric Urology)
Professional History
Richard S. Lee, MD is the Vice Chair, Research, Director of Pediatric Urologic Oncology, Director of Pediatric Urologic Transplantation, and the Co-Director of the Bladder Exstrophy Program. He is a board-certified pediatric urologist specializing in complex genitourinary reconstruction, including bladder exstrophy and other complex pelvic malformations, pediatric urologic oncology, pediatric renal transplantation and reconstruction, and robotic surgery. Dr. Lee received his undergraduate degree in Chemical Engineering at Princeton University and his medical degree at Jefferson Medical College. He completed his 6-year Urologic Surgery residency at the University of Washington and then trained in a 3-year pediatric urology fellowship at Boston Children’s Hospital, Harvard Medical School.
Dr. Lee has multiple research interests each with a strong focus on preservation of kidney function. His laboratory focuses on identifying urinary biomarkers of kidney injury, kidney obstruction and infection. He has received numerous research grants for his work and has been continuously federally funded by the National Institutes of Health (NIH) since 2007.
Publications
Multiomics analysis unveils an inosine-sensitive DNA damage response in neurogenic bladder after spinal cord injury. View Abstract
Long-Term Urinary and Sexual Outcomes in Pediatric Genitourinary Rhabdomyosarcoma Survivors: A Qualitative Study. View Abstract
Integrated omics analysis unveils a DNA damage response to neurogenic injury. View Abstract
Ureteropelvic Junction Obstruction/Hydronephrosis. View Abstract
Long-term Urological Outcomes in Pelvic Genitourinary Rhabdomyosarcoma: A 48-Year Single-center Experience. View Abstract
Prenatal Diagnosis of Bladder Exstrophy and OEIS over 20 Years. View Abstract
Copy Number Variation Analysis Facilitates Identification of Genetic Causation in Patients with Congenital Anomalies of the Kidney and Urinary Tract. View Abstract
Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction. View Abstract
Primary and secondary vaginal reconstruction with autologous buccal mucosa and intravaginal wound vacuum therapy. View Abstract
Malignancy Yield of Testis Pathology in Older Boys and Adolescents with Cryptorchidism. View Abstract
The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study. View Abstract
Proteomic Discovery of Noninvasive Biomarkers Associated With Sport-Related Concussions. View Abstract
Urinary Tract Infections in Children with Vesicoureteral Reflux Are Accompanied by Alterations in Urinary Microbiota and Metabolome Profiles. View Abstract
Uromodulin Isolation and Its N-Glycosylation Analysis by NanoLC-MS/MS. View Abstract
Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome. View Abstract
Modeling dynamic radial contrast enhanced MRI with linear time invariant systems for motion correction in quantitative assessment of kidney function. View Abstract
An in-depth Comparison of the Pediatric and Adult Urinary N-glycomes. View Abstract
Correction to: Prospective pediatric study comparing glomerular filtration rate estimates based on motion-robust dynamic contrast-enhanced magnetic resonance imaging and serum creatinine (eGFR) to 99mTc DTPA. View Abstract
Accuracy of Ultrasound in Identifying Renal Scarring as Compared to DMSA Scan. View Abstract
Prospective pediatric study comparing glomerular filtration rate estimates based on motion-robust dynamic contrast-enhanced magnetic resonance imaging and serum creatinine (eGFR) to 99mTc DTPA. View Abstract
Characterizing Patients with Recurrent Urinary Tract Infections in Vesicoureteral Reflux: A Pilot Study of the Urinary Proteome. View Abstract
Feed and wrap magnetic resonance urography provides anatomic and functional imaging in infants without anesthesia. View Abstract
CAKUT and Autonomic Dysfunction Caused by Acetylcholine Receptor Mutations. View Abstract
Renal outcomes of neonates with early presentation of posterior urethral valves: a 10-year single center experience. View Abstract
Interobserver and Intra-Observer Reliability of the Urinary Tract Dilation Classification System in Neonates: A Multicenter Study. View Abstract
Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract. View Abstract
Collaborating with our adult colleagues: A case series of robotic surgery for suspicious and cancerous lesions in children and young adults performed in a free-standing children's hospital. View Abstract
Has the robot caught up? National trends in utilization, perioperative outcomes, and cost for open, laparoscopic, and robotic pediatric pyeloplasty in the United States from 2003 to 2015. View Abstract
Identification of novel non-invasive biomarkers of urinary chronic pelvic pain syndrome: findings from the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. View Abstract
Urinary NGAL deficiency in recurrent urinary tract infections. View Abstract
Biomarkers for Wilms Tumor: A Brave New World. View Abstract
Urinary Proteomics Yield Pathological Insights for Ureteropelvic Junction Obstruction. View Abstract
Universal Solid-Phase Reversible Sample-Prep for Concurrent Proteome and N-Glycome Characterization. View Abstract
Targeted sequencing of 96 renal developmental microRNAs in 1213 individuals from 980 families with congenital anomalies of the kidney and urinary tract. View Abstract
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases. View Abstract
Mutations in TBX18 Cause Dominant Urinary Tract Malformations via Transcriptional Dysregulation of Ureter Development. View Abstract
Dual modifications strategy to quantify neutral and sialylated N-glycans simultaneously by MALDI-MS. View Abstract
Can we do better? View Abstract
Multi-planar dynamic contrast-enhanced ultrasound assessment of blood flow in a rabbit model of testicular torsion. View Abstract
The GlycoFilter: a simple and comprehensive sample preparation platform for proteomics, N-glycomics and glycosylation site assignment. View Abstract
An in-depth comparison of the male pediatric and adult urinary proteomes. View Abstract
SweetSEQer, simple de novo filtering and annotation of glycoconjugate mass spectra. View Abstract
A classifier based on accurate mass measurements to aid large scale, unbiased glycoproteomics. View Abstract
PNGase F catalyzes de-N-glycosylation in a domestic microwave. View Abstract
Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection. View Abstract
Costs and consequences of universal sibling screening for vesicoureteral reflux: decision analysis. View Abstract
One-step sample concentration, purification, and albumin depletion method for urinary proteomics. View Abstract
The predictive value of the first postnatal ultrasound in children with antenatal hydronephrosis. View Abstract
Sonourethrogram to manage adolescent anterior urethral stricture. View Abstract
Radiation dose and screening for vesicoureteral reflux. View Abstract
Robot-assisted laparoscopic nephrectomy and contralateral ureteral reimplantation in children. View Abstract
Biofeedback training for lower urinary tract symptoms: factors affecting efficacy. View Abstract
Ultrasound versus computerized tomography for evaluating urolithiasis. View Abstract
Nomograms for predicting annual resolution rate of primary vesicoureteral reflux: results from 2,462 children. View Abstract
Proteomics and opportunities for clinical translation in urological disease. View Abstract
Biomarkers for pediatric urological disease. View Abstract
Perinatal Urology View Abstract
Pediatric Laparoscopic Nephrectomy / Partial Nephrectomy View Abstract
Robot assisted laparoscopic partial nephrectomy: a viable and safe option in children. View Abstract
Optimizing sample handling for urinary proteomics. View Abstract
Does the Deflux procedure reduce the incidence of urinary tract infections in children with vesicoureteral reflux? View Abstract
Temporal variations of the postnatal rat urinary proteome as a reflection of systemic maturation. View Abstract
Robot-assisted laparoscopic ileal bladder augmentation: defining techniques and potential pitfalls. View Abstract
Obstruction of the Urinary Tract, including Hydronephrosis View Abstract
Laparoscopic reoperative pediatric pyeloplasty with robotic assistance. View Abstract
Early results of robot assisted laparoscopic lithotomy in adolescents. View Abstract
Ureteral complications in renal transplantation: a comparison of the Lich-Gregoir versus the Taguchi technique. View Abstract
Determining the optimal method of extracting proteins from urine for proteomic biomarker discovery View Abstract
Health A to Z: Male Infertility View Abstract
Health A to Z: Phimosis and Paraphimosis View Abstract
Health A to Z: Priapism View Abstract
Ask the Expert: Cystoscopy View Abstract
Can a complete primary repair approach be applied to cloacal exstrophy? View Abstract
Global methods for protein glycosylation analysis by mass spectrometry. View Abstract
Applying the ALARA concept to the evaluation of vesicoureteric reflux. View Abstract
Antenatal hydronephrosis as a predictor of postnatal outcome: a meta-analysis. View Abstract
Robotic surgery for ureteropelvic junction obstruction. View Abstract
Health A to Z: Peyronies Disease View Abstract
Ask the Expert: Radiation treatment and the bladder View Abstract
A proteomics platform based on spectrum alignment for de novo sequencing by LTQ FT MS View Abstract
The SeqR – a software tool for the analysis of high accuracy mass spectral data View Abstract
Health A to Z: Impotence View Abstract
Health A to Z: Retrograde Ejaculation View Abstract
Pediatric robot assisted laparoscopic dismembered pyeloplasty: comparison with a cohort of open surgery. View Abstract
Pediatric retroperitoneal laparoscopic partial nephrectomy: comparison with an age matched cohort of open surgery. View Abstract
Indirect recognition of MHC class I allopeptides accelerates lung allograft rejection in miniature swine. View Abstract
Health A to Z: Epididymitis and Orchitis View Abstract
Commentary on: Timing of Follow-up Voiding Cystourethrogram in Children with Primary Vesicoureteral Reflux: Development and Application of a Clinical Algorithm View Abstract
Symptomatic refluxing distal ureteral stumps after nephroureterectomy and heminephroureterectomy. What should we do? View Abstract
Molecular cloning and characterization of canine ICOS. View Abstract
Hematopoietic stem cell transplantation does not restore dystrophin expression in Duchenne muscular dystrophy dogs. View Abstract
Intracorporeal laparoscopic appendicovesicostomy: a case report of a novel approach. View Abstract
Vasoepididymostomy View Abstract
Traumatic renal artery pseudoaneurysm: diagnosis and management techniques. View Abstract
FTY720 does not abrogate acute graft-versus-host disease in the dog leukocyte antigen-nonidentical unrelated canine model. View Abstract
Induction of tolerance to heart transplants by simultaneous cotransplantation of donor kidneys may depend on a radiation-sensitive renal-cell population. View Abstract
Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates. View Abstract
Intermediate outcomes of dual renal allografts: the University of Washington experience. View Abstract
Intermediate outcomes of dual renal allografts. View Abstract
Survival of small bowel transplants in canine mixed hematopoietic chimeras: preliminary results. View Abstract
Percutaneous central dual-lumen catheter for apheresis in the canine. View Abstract
A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes. View Abstract
Treatment outcomes in localized prostate cancer: a patient-oriented approach. View Abstract
Salvage anterior C1-C2 screw fixation and arthrodesis through the lateral approach in a patient with a symptomatic pseudoarthrosis. View Abstract
Cervical Orthoses: A biomechanical and functional review View Abstract
An Examination of the Application of a Proton Exchange Membrane Fuel Cell for Cogeneration in a Hospital View Abstract
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