Roger Breitbart, MD
Chief Emeritus, Division of Inpatient Cardiology; Senior Cardiologist, Department of Cardiology
Assistant Professor of Pediatrics, Harvard Medical School
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Roger Breitbart, MD
Chief Emeritus, Division of Inpatient Cardiology; Senior Cardiologist, Department of Cardiology
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Haverford College
1977
Haveford
PA
Medical School
Harvard Medical School
1981
Boston
MA
Internship
Pediatrics
Boston Children's Hospital
1982
Boston
MA
Residency
Pediatrics
Boston Children's Hospital
1984
Boston
MA
Fellowship
Pediatric Cardiology
Boston Children's Hospital
1989
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Cardiology)
Publications
Multiphysiologic State Computational Fluid Dynamics Modeling for Planning Fontan With Interrupted Inferior Vena Cava. View Abstract
Factors associated with morbidity, mortality, and hemodynamic failure after biventricular conversion in borderline hypoplastic left hearts. View Abstract
Toxocara Myopericarditis and Cardiac Magnetic Resonance Imaging in a Young Girl. View Abstract
Parent and Physician Understanding of Prognosis in Hospitalized Children With Advanced Heart Disease. View Abstract
Value of Troponin Testing for Detection of Heart Disease in Previously Healthy Children. View Abstract
Delayed Presentation of Traumatic Pericardial Rupture: Diagnostic and Surgical Considerations for Treatment. View Abstract
Staged ventricular recruitment in patients with borderline ventricles and large ventricular septal defects. View Abstract
Longitudinal Outcomes of Patients With Single Ventricle After the Fontan Procedure. View Abstract
Truncus arteriosus versus tetralogy of Fallot with pulmonary atresia. View Abstract
De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. View Abstract
Survival data and predictors of functional outcome an average of 15?years after the Fontan procedure: the pediatric heart network Fontan cohort. View Abstract
Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. View Abstract
Stented bovine jugular vein graft (Melody valve) for surgical mitral valve replacement in infants and children. View Abstract
The relationship of patient medical and laboratory characteristics to changes in functional health status in children and adolescents after the Fontan procedure. View Abstract
De novo mutations in histone-modifying genes in congenital heart disease. View Abstract
Cardiac performance and quality of life in patients who have undergone the Fontan procedure with and without prior superior cavopulmonary connection. View Abstract
Outcome after repair of atrioventricular septal defect with tetralogy of Fallot. View Abstract
Late status of Fontan patients with persistent surgical fenestration. View Abstract
Factors associated with serum brain natriuretic peptide levels after the Fontan procedure. View Abstract
The Fontan patient: inconsistencies in medication therapy across seven pediatric heart network centers. View Abstract
Laboratory measures of exercise capacity and ventricular characteristics and function are weakly associated with functional health status after Fontan procedure. View Abstract
De novo copy number variants identify new genes and loci in isolated sporadic tetralogy of Fallot. View Abstract
Contemporary outcomes after the Fontan procedure: a Pediatric Heart Network multicenter study. View Abstract
Functional status, heart rate, and rhythm abnormalities in 521 Fontan patients 6 to 18 years of age. View Abstract
Genomics of congenital heart disease View Abstract
Functional state of patients with heterotaxy syndrome following the Fontan operation. View Abstract
Etiology, management, and outcome of pediatric pericardial effusions. View Abstract
Altered blood pressure responses and normal cardiac phenotype in ACE2-null mice. View Abstract
Synthetic Oligonucleotide Multiplex Ligation-dependent Probe Amplification (MLPA) for the Detection of Novel Deletions in Candidate Genes Causing Tetralogy of Fallot View Abstract
CARK, a novel cacardiac specific kinase, mediates structural remodeling and contractile function following myocardial infarction View Abstract
Pericardial Diseases View Abstract
Tetralogy of Fallot View Abstract
Sarcomeric genes involved in reverse remodeling of the heart during left ventricular assist device support. View Abstract
Right ventricular pseudoaneurysm after modified Norwood procedure. View Abstract
Heart block, ventricular tachycardia, and sudden death in ACE2 transgenic mice with downregulated connexins. View Abstract
Array transcription profiling: molecular phenotyping of rodent cardiovascular models View Abstract
Atherosclerosis and cancer: common molecular pathways of disease development and progression. View Abstract
Atherosclerosis: a cancer of the blood vessels? View Abstract
Expression of neutrophil collagenase (matrix metalloproteinase-8) in human atheroma: a novel collagenolytic pathway suggested by transcriptional profiling. View Abstract
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. View Abstract
Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development. View Abstract
Differential rescue of visceral and cardiac defects in Drosophila by vertebrate tinman-related genes. View Abstract
Zebrafish: genetic and embryological methods in a transparent vertebrate embryo. View Abstract
A new tinman-related gene, nkx2.7, anticipates the expression of nkx2.5 and nkx2.3 in zebrafish heart and pharyngeal endoderm. View Abstract
Three zebrafish MEF2 genes delineate somitic and cardiac muscle development in wild-type and mutant embryos. View Abstract
Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. View Abstract
Recent advances in the Laboratory of Molecular and Cellular Cardiology. View Abstract
A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage. View Abstract
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. View Abstract
Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors. View Abstract
Alternative splicing is an efficient mechanism for the generation of protein diversity: contractile protein genes as a model system. View Abstract
Tissue specific alternative splicing in the troponin T multigene family View Abstract
Alternative splicing of contractile protein minigene constructs is directed by cis and trans mechanisms View Abstract
Developmentally induced, muscle-specific trans factors control the differential splicing of alternative and constitutive troponin T exons. View Abstract
Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes. View Abstract
Promoter selection and alternative pre-mRNA splicing are used to generate complex contractile protein phenotypes View Abstract
Complete nucleotide sequence of the fast skeletal troponin T gene. Alternatively spliced exons exhibit unusual interspecies divergence. View Abstract
Alternative splicing: a common mechanism for the generation of contractile protein diversity from single genes View Abstract
Intricate combinatorial patterns of exon splicing generate multiple regulated troponin T isoforms from a single gene. View Abstract
Conversion of thyroxine to triiodothyronine in the anterior pituitary gland and the influence of this process on thyroid status. View Abstract
Comparison of thyroxine and 3,3',5'-triiodothyronine metabolism in rat kidney and liver homogenates. View Abstract
Locations