Sulpicio Soriano, II, MD

BCH Endowed Chair, Pediatric Neuroanesthesia; Co-Director, Neuroanesthesia Program; Senior Associate in Perioperative Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School
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Sulpicio Soriano II, MD

Sulpicio Soriano, II, MD

BCH Endowed Chair, Pediatric Neuroanesthesia; Co-Director, Neuroanesthesia Program; Senior Associate in Perioperative Anesthesia, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School

Medical Services

Languages
English
Education
Medical School
University of Pennsylvania School of Medicine
1985
Philadelphia
PA
Internship
St. Mary's Hospital and Medical Center
1986
San Francisco
CA
Residency
University of California Davis Medical Center
1989
Sacramento
CA
Fellowship
Boston Children's Hospital
1990
Boston
MA
Certifications
American Board of Anesthesiology (General)

Publications

Dexmedetomidine and Clonidine Attenuate Sevoflurane-Induced Tau Phosphorylation and Cognitive Impairment in Young Mice via a-2 Adrenergic Receptor. View Abstract
Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes. View Abstract
The Unspoken Question! View Abstract
Is Anesthesia Bad for the Brain? Current Knowledge on the Impact of Anesthetics on the Developing Brain. View Abstract
Does general anesthesia affect neurodevelopment in infants and children? View Abstract
The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. View Abstract
Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial. View Abstract
A Summary of Preclinical Poster Presentations at the Sixth Biennial Pediatric Anesthesia Neurodevelopment Assessment (PANDA) Symposium. View Abstract
Anesthesia and the developing brain: A way forward for laboratory and clinical research. View Abstract
Sevoflurane Acts on Ubiquitination-Proteasome Pathway to Reduce Postsynaptic Density 95 Protein Levels in Young Mice. View Abstract
Differences in Blood Pressure in Infants After General Anesthesia Compared to Awake Regional Anesthesia (GAS Study-A Prospective Randomized Trial). View Abstract
Thinking, fast and slow: highlights from the 2016 BJA seminar on anaesthetic neurotoxicity and neuroplasticity. View Abstract
Coenzyme Q10 reduces sevoflurane-induced cognitive deficiency in young mice. View Abstract
From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. View Abstract
Anesthesia, brain changes, and behavior: Insights from neural systems biology. View Abstract
Dexmedetomidine-Induced Neuroapoptosis Is Dependent on Its Cumulative Dose. View Abstract
Leukocyte function-associated antigen-1 deficiency impairs responses to polymicrobial sepsis. View Abstract
Imaging the progression of anesthetic-induced neurotoxicity: a leap toward translational relevance. View Abstract
The role of macrophage 1 antigen in polymicrobial sepsis. View Abstract
Anesthesia for intracranial surgery in infants and children. View Abstract
Progress in anesthesia and management of the newborn surgical patient. View Abstract
Not just neuroanesthesia, but Pediatric neuroanesthesia! View Abstract
Anesthetic neurotoxicity. View Abstract
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. View Abstract
Population pharmacokinetics of tranexamic acid in paediatric patients undergoing craniosynostosis surgery. View Abstract
Role of glycogen synthase kinase-3ß in ketamine-induced developmental neuroapoptosis in rats. View Abstract
Morphine-enhanced apoptosis in selective brain regions of neonatal rats. View Abstract
Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairment. View Abstract
Neuroanesthesiology fellowship training: curricular guidelines from the Society for Neuroscience in Anesthesiology and Critical Care. View Abstract
Perioperative central nervous system injury in neonates. View Abstract
Neurotoxicity of ketamine: known unknowns. View Abstract
Noxious stimulation attenuates ketamine-induced neuroapoptosis in the developing rat brain. View Abstract
General anesthetics in pediatric anesthesia: influences on the developing brain. View Abstract
Anesthetic concerns for pediatric patients in an intraoperative MRI suite. View Abstract
Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomes. View Abstract
Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial. View Abstract
Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 function. View Abstract
Endoscopic strip craniectomy in early infancy: the initial five years of anesthesia experience. View Abstract
Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1. View Abstract
Detection of intestinal inflammation by MicroPET imaging using a (64)Cu-labeled anti-beta(7) integrin antibody. View Abstract
Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. View Abstract
Thinking about the neurotoxic effects of sedatives on the developing brain. View Abstract
Acute intraoperative neurogenic pulmonary edema during endoscopic ventriculoperitoneal shunt revision. View Abstract
Thinking about the neurotoxic effects of sedatives on the developing brain View Abstract
Detection of intestinal inflammation by PET imaging using a 64Cu-labeled anti-ƒÒ7 integrin antibody View Abstract
Is anesthesia bad for the newborn brain? View Abstract
Clinical research approaches to studying pediatric anesthetic neurotoxicity. View Abstract
Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brains. View Abstract
Anesthesia for Pediatric Neurosurgery and Traumatic Brain Injury View Abstract
Pediatric Neuroanesthesia, Winn R (ed) View Abstract
The volatile anesthetic agent isoflurane perturbs the conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity View Abstract
SNACC: Basic and Clinical Neurosciences in Perfect Harmony View Abstract
The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavity. View Abstract
CON: The toxic effects of anesthetics in the developing brain: the clinical perspective. View Abstract
An assessment of the effects of general anesthetics on developing brain structure and neurocognitive function. View Abstract
Central nervous system inflammation. View Abstract
Anesthetic considerations and postoperative ICU care View Abstract
The Central Nervous System: Pediatric Neuroanesthesia View Abstract
Pediatric Neuroanesthesia View Abstract
Pediatric Neuroanesthesia View Abstract
Pediatric Neuroanesthesia View Abstract
Recognition and Alleviation of Pain in Laboratory Animals View Abstract
Pediatric Neuroanesthesia View Abstract
Detection of unanticipated intracranial hemorrhage during intraoperative magnetic resonance image-guided neurosurgery. Report of two cases. View Abstract
Pediatric neuroanesthesia. View Abstract
Lidocaine pretreatment for the prevention of propofol-induced transient motor disturbances in children during anesthesia induction: a randomized controlled trial in children undergoing invasive hematologic procedures. View Abstract
Anesthesia for epilepsy surgery in children. View Abstract
Summary proceedings from the neonatal pain-control group. View Abstract
Anesthetic management of pial synangiosis and intracranial hemorrhage with a Fontan circulation. View Abstract
Let's not throw the baby out with the bath water: potential neurotoxicity of anesthetic drugs in infants and children. View Abstract
Cerebrospinal fluid may mediate CNS ischemic injury. View Abstract
Analgesia and anesthesia for neonates: study design and ethical issues. View Abstract
Anesthesia and analgesia during and after surgery in neonates. View Abstract
Anesthetics and brain toxicity. View Abstract
Of mice and men: should we extrapolate rodent experimental data to the care of human neonates? View Abstract
Society of Neurosurgical Anesthesia and Critical Care (SNACC) Problem-based learning discussion: 3 month old boy with saggital craniosynostosis SNACC Website http://www.snacc.org/ed/casedisc/Craniosynostosis.pdf View Abstract
Anesthetic agents and the immature brain: are these toxic or therapeutic? View Abstract
Perioperative management of diabetes insipidus in children. View Abstract
Does anaesthesia harm the developing brain--evidence or speculation? View Abstract
Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis. View Abstract
Perioperative management of diabetes insipidus in children [corrected]. View Abstract
Antiepileptic-induced resistance to neuromuscular blockers: mechanisms and clinical significance. View Abstract
Society for Neurosurgical Anesthesia and Critical Care (SNACC) Bibliography, SNACC website: http://www.snacc.org/ed/bib/StartBIB.html View Abstract
Pediatric Neuroanesthesia View Abstract
Society of Neurosurgical Anesthesia and Critical Care (SNACC) newsletter: report of the 2002 annual meeting, Orlando, Florida. View Abstract
Repeated administration of ketamine may lead to neuronal degeneration in the developing rat brain. View Abstract
Anaesthetic management of children with tuberous sclerosis. View Abstract
Pediatric neuroanesthesia. View Abstract
Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injury. View Abstract
Levels of soluble adhesion molecules are elevated in the cerebrospinal fluid of children with moyamoya syndrome. View Abstract
Neuroanesthesia. Innovative techniques and monitoring. View Abstract
Hemostatic changes in pediatric neurosurgical patients as evaluated by thrombelastograph. View Abstract
Gentle dorsal root retraction and dissection can cause areflexia: implications for intraoperative monitoring during "selective" partial dorsal rhizotomy. View Abstract
Pharmacokinetics and pharmacodynamics of vecuronium in children receiving phenytoin or carbamazepine for chronic anticonvulsant therapy. View Abstract
Pediatric Neuroanesthesia View Abstract
The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children. View Abstract
Onset and duration of action of rocuronium in children receiving chronic anticonvulsant therapy. View Abstract
P- and E-selectin-deficient mice are susceptible to cerebral ischemia-reperfusion injury. View Abstract
Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. View Abstract
Anesthesia for Pediatric Neurosurgery View Abstract
Rebound swelling of astroglial cells exposed to hypertonic mannitol. View Abstract
Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. View Abstract
ICAM-1 dependent pathway is not involved in the development of neuronal apoptosis after transient focal cerebral ischemia. View Abstract
Surgical airway, rigid bronchoscopy, and transtracheal jet ventilation in the pediatric patient View Abstract
Sevoflurane depresses myocardial contractility less than halothane during induction of anesthesia in children. View Abstract
Effects of ondansetron on emesis in the first 24 hours after craniotomy in children. View Abstract
Cerebral blood flow velocity after mannitol infusion in children. View Abstract
Intercellular adhesion molecule-1-deficient mice are less susceptible to cerebral ischemia-reperfusion injury. View Abstract
The critical importance of stimulus intensity in intraoperative monitoring for partial dorsal rhizotomy. View Abstract
Resection of a massive sacrococcygeal teratoma using hypothermic hypoperfusion: a novel use of extracorporeal membrane oxygenation. View Abstract
Neuroanesthesia. View Abstract
Anesthesia for stereotactic radiosurgery in children. View Abstract
Nitrous oxide depresses the H-reflex in children with cerebral palsy. View Abstract
Doppler sensor placement during neurosurgical procedures for children in the prone position. View Abstract
H reflex studies in cerebral palsy patients undergoing partial dorsal rhizotomy. View Abstract
Anesthetic management of children with moyamoya syndrome. View Abstract
EEG power changes are more sensitive than spectral edge frequency variation for detection of cerebral ischemia during carotid artery surgery: a prospective assessment of processed EEG monitoring. View Abstract
Neonatal surgical emergencies View Abstract
Posterior fossa craniotomy View Abstract
A recommendation for reduced lidocaine dosage during intravenous regional bretylium treatment of reflex sympathetic dystrophy. View Abstract
Osteomalacia in a night nurse View Abstract