Current Environment:

Principal Investigator

Read more about Richard Gregory, PhD

Principal Investigator, Gregory Lab

Professor, Department of Biological Chemistry and Molecular Pharmacology, and Department of Pediatrics, Harvard Medical School, Harvard Stem Cell Institute

Postdoctoral Fellows

Esteban Orellana, PhD Esteban Orellana, PhD
esteban.orellana@childrens.harvard.edu

Esteban joined the Gregory Laboratory in May 2018. He completed his graduate studies at Purdue University. His project involved ligand-mediated miRNA delivery and miRNA combinatorial therapeutics for cancer. Esteban's current research focuses on RNA methylation and its role in gene regulation and cancers including glioblastoma and sarcomas.

 

Jia Cui, PhD Jia Cui, PhD
jia.cui@childrens.harvard.edu

Jia received her PhD in 2018 from the University of Alabama at Birmingham, where she studied the post-transcriptional regulation of anti-apoptotic protein MCL1 in cancer. In August 2018 she joined the Gregory Lab as a postdoctoral fellow. She is interested in the field of RNA biology. Jia's current research focuses on RNA modifications and their roles in gene regulation and cancer.

 

Jiazhi Li, PhD Jiazhi Li, PhD
jiazhi.li@childrens.harvard.edu

Jiazhi received her PhD in 2018 from Institute of Biophysics, Chinese Academy of Sciences. Her doctoral program focused on the structural and mechanistic basis of the CRISPR-Cas system. She joined the Gregory Lab in April 2019 and started her research on investigating mechanisms of posttranscriptional gene regulation using a structural and functional combining method.

 

Xin Yang, PhD Xin Yang, PhD
xin.yang@childrens.harvard.edu

Xin received his PhD in 2018 from Beijing Institute of Genomics, Chinese Academy of Sciences. He studied the topology of mRNA m5C methylomes and the essential roles of m5C in mRNA export regulation. Xin also studied m6A and its role in the dynamic regulation of co-transcriptional R-loop formation and transcription termination. Xin joined the Gregory Lab in September 2019 and started his research on RNA modifications and their roles in gene regulation and cancer.

 

Xushen Xiong, PhD Xushen Xiong, PhD
xushen.xiong@childrens.harvard.edu

Xushen obtained his PhD degree in 2019 from Peking University in China, where he received training in chemical biology, specifically in the epitranscriptomics field. He then joined the Gregory Lab as a postdoc, co-supervised by Professor Manolis Kellis at MIT. Xushen is currently working on understanding the regulatory networks of RNA modification in diseases, by employing both computational and experimental approaches.

 

Julia Ramirez-Moya, PhD

Julia Ramirez-Moya, PhD
julia.ramirezmoya@childrens.harvard.edu

Julia received her PhD in 2021 from "Alberto Sols" Biomedical Research Institute at Madrid, Spain. She studied RNA regulatory mechanisms in cancer, such as miRNA regulation and A-to-I RNA editing. In April 2021 she joined the Gregory lab and her current research focuses on tRNA editing and its role in cancer.
 

Erdem Sendinc, PhD

Erdem Sendinc, PhD
erdem.sendinc@childrens.harvard.edu​​​​​​​

After collaborating with the Gregory Lab on various projects, Erdem joined the lab in 2022. He is interested in investigating the roles of RNA modifications in RNA metabolism and cellular biology. He utilizes RNA mass spectrometry to characterize chemical modifications in RNA sequences. His current research focuses on mRNA and tRNA modifying enzymes in the context of regulation of gene expression.

Other Lab Members

small BCH male avatar David Nelson
Laboratory Manager 
david.nelson@childrens.harvard.edu

Lab Alumni

Robert LaPierre
Lab Manager (2006-2013)
Current: Physician Assistant, New England Neurological Associates P.C.

Elena Piskounova
Grad Student (2007-2011)
Current: Assistant Professor, Weill-Cornell Medical School

John P. Hagan
Postdoc (2008-2012)
Current: Assistant Professor, University of Texas Health Sciences Center, Houston, TX

Hao-Ming Chang
Postdoc (2008-2012)
Current: Reseach Scientist, Alexion Pharmaceuticals Inc.

Robinson Triboulet
Postdoc (2008-2018)
Current: Research Scientist, Twentyeight-seven Therapeutics

James Thornton
Grad Student (2009-2013)
Current: Senior Director of Business Development, Codiak BioSciences

Natalia J. Martinez
Postdoc (2009-2013)
Current: Research Scientist, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)

Masaki Mori
Postdoc (2011-2014)
Current: Associate Professor, Shiga University of Medical Science, Japan

Yoshinori Nishimoto
Postdoc (2013-2016)
Current: Neurologist, Keio University School of Medicine, Japan

Peng Du
Postdoc (2012-2018)
Current: Assistant Professor, Peking University, China

Shuibin Lin
Postdoc (2012-2018)
Current: Assistant Professor, Sun Yat-sen University, China

Junho Choe
Postdoc (2014-2019)
Current: Assistant Professor, Hanyang University, Korea

Carmen Rios
Lab Manager (2013-2020)
Current: Research Operations Manager, Broad Institute of MIT and Harvard

Mehdi Pirouz
Postdoc (2014-2021)
Current: Assistant Professor, Rutgers Medical School and Center for Advanced Biotechnology and Medicine

Qi Liu
Postdoc (2017-2021)
Current: Assistant Professor, Guangdong School of Agricultural Science

Quentin Hahn
Research Assistant (2020-2022)
Current: Graduate Student, UNC Chapel Hill

Elisabeth Siegal
Visiting Graduate Student (2021-2022)
Current: University of Utrecht Medical School