Researcher | Research Overview
Dongwon Lee’s research focuses on discovering the genomic basis of pediatric kidney diseases from the perspective of transcriptional regulation in a cell-type-resolved manner. Dongwon has developed several computational methods based on machine-learning techniques and epigenomics data to predict cis-regulatory elements (CREs) and CRE variants from their primary DNA sequences. He demonstrated that the CRE variants predicted by these methods significantly contribute to the heritability of human traits and diseases in a tissue-specific way. He will extend these methodologies and develop new methods to build a unified framework that can illuminate the transcriptional regulatory network.
Researcher | Research Background
Dongwon Lee received his PhD from the Department of Biomedical Engineering at the Johns Hopkins University in 2013 and completed postdoctoral research at the Center for Human Genetics and Genomics at NYU School of Medicine.