- Glaucoma is a condition in which the normal fluid pressure inside the eyes (intraocular pressure or IOP) slowly rises as a result of the fluid aqueous humor — which normally flows in and out of the eye — not being able to drain properly. Instead, the fluid collects and causes pressure damage to the optic nerve (a bundle of more than 1 million nerve fibers that connects the retina with the brain) and loss of vision.
Glaucoma is classified according to the age of onset. Glaucoma that begins before the child is 3 years old is called infantile or congenital (present at birth) glaucoma. Glaucoma that occurs in a child is called childhood glaucoma.
- A cataract is a clouding or opaque area over the lens of the eye, an area that is normally transparent. As this thickening occurs, it prevents light rays from passing through the lens and focusing on the retina, the light-sensitive tissue lining located in the back of the eye. This clouding is caused when some of the protein that makes up the lens begins to clump together and interferes with vision.
Cataracts can affect either one eye (unilateral) or both eyes (bilateral). Cataracts in children are uncommon. A child may be born with the disease (congenital), or it may develop later in life (acquired). Possible causes of cataracts include:
- Trauma
- Diabetes
- Poisoning
- Steroid use
- Other childhood diseases, such as rheumatoid arthritis
- Complications from other eye diseases, such as glaucoma
The majority of congenital cataracts (those present at birth) are present in children who also have other eye problems or other health problems. In about 25 percent of children born with congenital cataracts, the condition is due to a genetic cause, such as a metabolic disorder (caused by an inherited enzyme deficiency) or a chromosome abnormality (i.e., Down syndrome).
Signs and symptoms of a cataract may include:
- Cloudy or blurry vision
- Decreased vision
- Lights appearing too bright and/or presenting a glare or surrounding halo
- White pupil upon flashlight examination
- Double vision
- Colors seem faded
- Increased nearsightedness, increasing the need to change eyeglass prescriptions
Treatment of cataracts usually involves surgery.
- Retinoblastoma is a rare cancer of the retina. The retina is the innermost layer of the eye, located at the back of the eye that receives light and images necessary for vision.
About 250 children in the United States are diagnosed with this type of cancer each year. It mostly occurs in children under the age of 5; the highest incidence of the disease occurs between infancy and age 2. Both males and females are affected equally. Retinoblastoma can occur in either eye, but in about 25 to 30 percent of the cases, the tumor is present in both eyes.
Signs and symptoms of retinoblastoma may include:
- Leukocoria: a white light reflex that occurs at certain angles when light is shown into the pupil
- Strabismus (also called "wandering eye" or "crossed-eyes"): a misalignment of the eyes in which one or both eyes do not appear to be "looking" in the same direction
- Pain or redness around the eye(s)
- Poor vision or change in child's vision
Treatment for retinoblastoma may include one, or more, of the following:
- Surgery
- Enucleation (removal of part or all of the eye or eyes involved with the tumor)
- Chemotherapy
- Radiation therapy
- Phototherapy (uses light to destroy the blood vessels that supply the tumor)
- Cryotherapy (uses a freezing process to destroy the tumor)
- Fitting and training for a prosthesis
- Blind or decreased vision adaptation training
- Supportive care (for the side effects of treatment)
- Antibiotics (to prevent/treat infection)