Michael Landzberg, MD
Director, Palliative Therapeutics in Congenital Heart Disease (PATCH); Immediate Past (and founding) Director, Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Program; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Medicine, Harvard Medical School
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Michael Landzberg, MD
Director, Palliative Therapeutics in Congenital Heart Disease (PATCH); Immediate Past (and founding) Director, Boston Adult Congenital Heart (BACH) and Pulmonary Hypertension Program; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Medicine, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Columbia University
1981
New York
NY
Medical School
Harvard Medical School
1985
Boston
MA
Internship
Columbia University
1988
New York
NY
Residency
Columbia University
1989
New York
NY
Fellowship
Brigham and Women's Hospital
1992
Boston
MA
Certifications
American Board of Internal Medicine (General)
American Board of Internal Medicine (Cardiovascular Disease)
Professional History
In addition to continuing his roles in the BACH group, Dr. Landzberg is developing skills and future programming in cardiovascular palliative care, clinician-patient communication and patient-centered care. Although we anticipate no change in the volume of Dr. Landzberg¹s outpatient visits, there may be changes in his clinical schedule from July 2018 until September 2019.
Publications
Adverse Childhood Experiences and Cardiovascular Outcomes in Adult Congenital Heart Disease: ACEs in ACHD. View Abstract
Palliative and End-of-Life Care During Critical Cardiovascular Illness: A Scientific Statement From the American Heart Association. View Abstract
Correlation between Olink and SomaScan proteomics platforms in adults with a Fontan circulation. View Abstract
Iatrogenic esophageal dysmotility as a barrier to transplantation in pulmonary arterial hypertension. View Abstract
Hopes, expectations, and informational needs in patients undergoing advanced heart failure therapy evaluations. View Abstract
The burden of psychological trauma and post-traumatic stress disorder among adults with congenital heart disease: PTSD in ACHD. View Abstract
Palliative Care in Adult Congenital Heart Disease-Associated Advanced Heart Disease. View Abstract
Corrigendum to 'The role of sensitization in post-transplant outcomes in adults with congenital heart disease sensitization in adults with congenital heart disease', Int. J. Cardiol. Congenit. Heart Dis., 8, June 2022, 100384. View Abstract
Timely PAH Identification in Adults With Repaired Congenital Heart Disease? The ACHD-QuERI Registry Insights. View Abstract
Feasibility of frailty screening among patients with advanced heart failure. View Abstract
Top Ten Tips Palliative Care Clinicians Should Know About Delivering Specialty-Aligned Palliative Care. View Abstract
Specialty-Aligned Palliative Care: Responding to the Needs of a Tertiary Care Health System. View Abstract
The role of sensitization in post-transplant outcomes in adults with congenital heart disease sensitization in adults with congenital heart disease. View Abstract
The Association of Lower Venous Disease to Outcomes in Adults With Fontan Physiology: CALF Revisited. View Abstract
Top Ten Tips Palliative Care Clinicians Should Know About Solid Organ Transplantation. View Abstract
Serial cardiac biomarker assessment in adults with congenital heart disease hospitalized for decompensated heart failure?. View Abstract
Tuning and external validation of an adult congenital heart disease risk prediction model. View Abstract
Management of acute cardiovascular complications in pregnancy. View Abstract
Associations Between Clinical Outcomes and a Recently Proposed Adult Congenital Heart Disease Anatomic and Physiological Classification System. View Abstract
Long-Term Fate of the Truncal Valve. View Abstract
Interobserver agreement of the anatomic and physiological classification system for adult congenital heart disease. View Abstract
Advanced Heart Failure Therapies for Adults With Congenital Heart Disease: JACC State-of-the-Art Review. View Abstract
Reducing radiation dose from myocardial perfusion imaging in subjects with complex congenital heart disease. View Abstract
Standardized outcomes in reproductive cardiovascular care: The STORCC initiative. View Abstract
Knowledge of Life-Long Cardiac Care by Adolescents and Young Adults with Congenital Heart Disease. View Abstract
Planned vaginal delivery and cardiovascular morbidity in pregnant women with heart disease. View Abstract
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
Evaluation of Macitentan in Patients With Eisenmenger Syndrome. View Abstract
Prospective cohort study of C-reactive protein as a predictor of clinical events in adults with congenital heart disease: results of the Boston adult congenital heart disease biobank. View Abstract
Disparities in Wait-List Outcomes for Adults With Congenital Heart Disease Listed for Heart Transplantation Before and Since Revision of Status I Listing. View Abstract
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
2018 AHA/ACC Guideline for the Management of Adults With Congenital Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. View Abstract
Relationship of Red Cell Distribution Width to Adverse Outcomes in Adults With Congenital Heart Disease (from the Boston Adult Congenital Heart Biobank). View Abstract
A Pilot Study of Inspiratory Muscle Training to Improve Exercise Capacity in Patients with Fontan Physiology. View Abstract
Congenital tricuspid valve disease can masquerade as primary idiopathic tricuspid regurgitation. View Abstract
Transition Education: Formative Steps, in Need of Direction. View Abstract
Association of Albuminuria With Major Adverse Outcomes in Adults With Congenital Heart Disease: Results From the Boston Adult Congenital Heart Biobank. View Abstract
A Randomized Trial Comparing Cardiac Rehabilitation to Standard of Care for Adults With Congenital Heart Disease. View Abstract
Hemodynamic and metabolic characteristics associated with development of a right ventricular outflow tract pressure gradient during upright exercise. View Abstract
Decline in peak oxygen consumption over time predicts death or transplantation in adults with a Fontan circulation. View Abstract
Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise: A Simultaneous Invasive-Noninvasive Comparison. View Abstract
Anomalous Aortic Origin of a Coronary Artery From the Inappropriate Sinus of Valsalva. View Abstract
Development of a Right Ventricular Outflow Tract Gradient During Upright Exercise: A Hemodynamic Observation. View Abstract
Predictors of Death in Contemporary Adult Patients With Eisenmenger Syndrome: A Multicenter Study. View Abstract
Liver health in adults with Fontan circulation: A multicenter cross-sectional study. View Abstract
Design and Implementation of a Prospective Adult Congenital Heart Disease Biobank. View Abstract
Estimated glomerular filtration rate and urine biomarkers in patients with single-ventricle Fontan circulation. View Abstract
Predictive value of biomarkers of hepatic fibrosis in adult Fontan patients. View Abstract
Emerging Research Directions in Adult Congenital Heart Disease: A Report From an NHLBI/ACHA Working Group. View Abstract
Anomalous origin of the coronary artery arising from the opposite sinus: prevalence and outcomes in patients undergoing coronary CTA. View Abstract
Galectin-3 Is Elevated and Associated With Adverse Outcomes in Patients With Single-Ventricle Fontan Circulation. View Abstract
Anticoagulation in patients with pulmonary arterial hypertension: An update on current knowledge. View Abstract
Transcatheter Therapies for the Treatment of Valvular and Paravalvular Regurgitation in Acquired and Congenital Valvular Heart Disease. View Abstract
Clinical applications of radionuclide imaging in the evaluation and management of patients with congenital heart disease. View Abstract
Survival of adults with ASD2: a call for a longitudinal clinical registry. View Abstract
Structural heart disease: tetralogy, transposition, and truncus, too? View Abstract
Implementation of the American College of Cardiology/American Heart Association 2008 Guidelines for the Management of Adults With Congenital Heart Disease. View Abstract
The care of adults with congenital heart disease across the globe: Current assessment and future perspective: A position statement from the International Society for Adult Congenital Heart Disease (ISACHD). View Abstract
Portal and centrilobular hepatic fibrosis in Fontan circulation and clinical outcomes. View Abstract
Tricuspid valve regurgitation in congenitally corrected transposition of the great arteries and a left ventricle to pulmonary artery conduit. View Abstract
Pheochromocytoma and paraganglioma in cyanotic congenital heart disease. View Abstract
Exercise oscillatory ventilation in patients with Fontan physiology. View Abstract
The impact of IMPACT: a game changer for congenital cardiology. View Abstract
Impaired exercise capacity following atrial septal defect closure: an invasive study of the right heart and pulmonary circulation. View Abstract
[Updated clinical classification of pulmonary hypertension]. View Abstract
Rare case of undiagnosed supracardiac total anomalous pulmonary venous return in an adult. View Abstract
Pulmonary arterial hypertension associated with congenital heart disease: recent advances and future directions. View Abstract
MDCT of congenital coronary artery fistulas. View Abstract
Durability of large diameter right ventricular outflow tract conduits in adults with congenital heart disease. View Abstract
Clinicians' perspectives on patient satisfaction in adult congenital heart disease clinics--a dimension of health care quality whose time has come. View Abstract
Patent foramen ovale closure vs medical therapy for stroke prevention: meta-analysis of randomized trials and review of heterogeneity in meta-analyses. View Abstract
Abnormal spirometry after the Fontan procedure is common and associated with impaired aerobic capacity. View Abstract
ACC/AHA/SCAI 2014 health policy statement on structured reporting for the cardiac catheterization laboratory: a report of the American College of Cardiology Clinical Quality Committee. View Abstract
ACC/AHA/SCAI 2014 health policy statement on structured reporting for the cardiac catheterization laboratory: a report of the American College of Cardiology Clinical Quality Committee. View Abstract
Specialized adult congenital heart care saves lives. View Abstract
Transient elastography may identify Fontan patients with unfavorable hemodynamics and advanced hepatic fibrosis. View Abstract
Transition and transfer of adolescents and young adults with pediatric onset chronic disease: the patient and parent perspective. View Abstract
The exceptional and far-flung manifestations of heart failure in Eisenmenger syndrome. View Abstract
Evolving perspectives on heart failure in adults with congenital heart disease. Preface. View Abstract
Updated clinical classification of pulmonary hypertension. View Abstract
Clinical research priorities in adult congenital heart disease. View Abstract
Right heart failure: toward a common language. View Abstract
Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice. View Abstract
Contemporary predictors of death and sustained ventricular tachycardia in patients with repaired tetralogy of Fallot enrolled in the INDICATOR cohort. View Abstract
Right heart failure: toward a common language. View Abstract
Outcomes of adolescents and adults undergoing primary Fontan procedure. View Abstract
Physical activity is associated with improved aerobic exercise capacity over time in adults with congenital heart disease. View Abstract
Effect of aspirin and warfarin therapy on thromboembolic events in patients with univentricular hearts and Fontan palliation. View Abstract
Patent foramen ovale: when is intervention warranted? View Abstract
Aortic valve dysfunction and aortic dilation in adults with coarctation of the aorta. View Abstract
Bloodstream infections occurring in patients with percutaneously implanted bioprosthetic pulmonary valve: a single-center experience. View Abstract
A simple echocardiographic method to estimate pulmonary vascular resistance. View Abstract
Improving heart disease knowledge and research participation in adults with congenital heart disease (the Health, Education and Access Research Trial: HEART-ACHD). View Abstract
Effect of inhaled iloprost on the exercise function of Fontan patients: a demonstration of concept. View Abstract
Prevalence and predictors of gaps in care among adult congenital heart disease patients: HEART-ACHD (The Health, Education, and Access Research Trial). View Abstract
The Changing Demographics of Congenital Heart Disease Hospitalizations in the United States, 1998 Through 2010. View Abstract
Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: initial clinical experience. View Abstract
MELD-XI score and cardiac mortality or transplantation in patients after Fontan surgery. View Abstract
Adult congenital heart disease incidence and consultation: a survey of general adult cardiologists. View Abstract
Left and right ventricular diastolic function in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. View Abstract
The effects of pregnancy on right ventricular remodeling in women with repaired tetralogy of Fallot. View Abstract
Adverse events rates and risk factors in adults undergoing cardiac catheterization at pediatric hospitals--results from the C3PO. View Abstract
Transcatheter closure of post-myocardial infarction ventricular septal rupture. View Abstract
Hospitalizations and mortality in the United States for adults with Down syndrome and congenital heart disease. View Abstract
Advance care planning and end-of-life management of adult patients with congenital heart disease. View Abstract
Lateral window sinus elevation technique: managing challenges and complications. View Abstract
Cardiovascular outcomes after the arterial switch operation for D-transposition of the great arteries. View Abstract
Aortic root dilatation in adults with surgically repaired tetralogy of fallot: a multicenter cross-sectional study. View Abstract
Balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension: a need for further dialogue, development, and collaborative study. View Abstract
Correlation of exercise response in repaired coarctation of the aorta to left ventricular mass and geometry. View Abstract
A shifting approach to management of the thoracic aorta in bicuspid aortic valve. View Abstract
Referral patterns and perceived barriers to adult congenital heart disease care: results of a survey of U.S. pediatric cardiologists. View Abstract
QRS duration and QRS fractionation on surface electrocardiogram are markers of right ventricular dysfunction and atrialization in patients with Ebstein anomaly. View Abstract
Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study. View Abstract
Multimodality imaging of a Gerbode defect. View Abstract
Single ventricle anatomy is associated with increased frequency of nonalcoholic cirrhosis. View Abstract
Rationale and design of an International Multicenter Registry of patients with repaired tetralogy of Fallot to define risk factors for late adverse outcomes: the INDICATOR cohort. View Abstract
Acute dyspnea in a young man with an old sternotomy. View Abstract
Closure or medical therapy for cryptogenic stroke with patent foramen ovale. View Abstract
The Adult Congenital and Pediatric Cardiology Section: increasing the opportunities for the congenital heart disease community within the American College of Cardiology. View Abstract
Parental knowledge regarding lifelong congenital cardiac care. View Abstract
Cerebral abscess due to persistent left superior vena cava draining into the left atrium. View Abstract
Resource use among adult congenital heart surgery admissions in pediatric hospitals: risk factors for high resource utilization and association with inpatient death. View Abstract
Maternal cardiovascular events during childbirth among women with congenital heart disease. View Abstract
Pathophysiology of chronic venous insufficiency in adults with a Fontan circulation (a pre-defined substudy of the CALF investigation). View Abstract
Risk factors for death after adult congenital heart surgery in pediatric hospitals. View Abstract
A case series of the anesthetic management of parturients with surgically repaired tetralogy of Fallot. View Abstract
Exercise testing identifies patients at increased risk for morbidity and mortality following Fontan surgery. View Abstract
Comparison of risk of hypertensive complications of pregnancy among women with versus without coarctation of the aorta. View Abstract
Pregnancy-related cardiac risk in women with congenital heart disease: is it over when it's over? View Abstract
Introduction: Adult congenital heart disease. View Abstract
Advances in transcatheter interventions in adults with congenital heart disease. View Abstract
Bicuspid aortic valve morphology. View Abstract
Study design of the CLOSURE I Trial: a prospective, multicenter, randomized, controlled trial to evaluate the safety and efficacy of the STARFlex septal closure system versus best medical therapy in patients with stroke or transient ischemic attack due to presumed paradoxical embolism through a patent foramen ovale. View Abstract
Arrhythmia burden in adults with surgically repaired tetralogy of Fallot: a multi-institutional study. View Abstract
Pregnancy outcomes in women with transposition of the great arteries and arterial switch operation. View Abstract
The CALF (Congenital Heart Disease in Adults Lower Extremity Systemic Venous Health in Fontan Patients) study. View Abstract
Pregnancy in patients with tetralogy of fallot: invited commentary. View Abstract
A preliminary look at duplicate testing associated with lack of electronic health record interoperability for transferred patients. View Abstract
Predictors of long-term adverse outcomes in patients with congenital coronary artery fistulae. View Abstract
Pregnant women with congenital heart disease: cardiac, anesthetic and obstetrical implications. View Abstract
Lung abscess in adults with tetralogy of fallot and pulmonary atresia. View Abstract
Serial cardiopulmonary exercise testing in patients with previous Fontan surgery. View Abstract
Atrial arrhythmias: a "call to arms" for congenital heart disease caregivers. View Abstract
Atrial septal defects versus ventricular septal defects in BREATHE-5, a placebo-controlled study of pulmonary arterial hypertension related to Eisenmenger's syndrome: a subgroup analysis. View Abstract
Obstetric outcomes in pregnant women with congenital heart disease. View Abstract
Percutaneous closure of patent foramen ovale and atrial septal defect in adults: the impact of clinical variables and hospital procedure volume on in-hospital adverse events. View Abstract
Not just big kids: closing atrial septal defects in adults older than 60 years. View Abstract
Recurrence of cerebrovascular events in young adults with a secundum atrial septal defect. View Abstract
ACC/AHA 2008 guidelines for the management of adults with congenital heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Develop Guidelines on the Management of Adults With Congenital Heart Disease). Developed in Collaboration With the American Society of Echocardiography, Heart Rhythm Society, International Society for Adult Congenital Heart Disease, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. View Abstract
ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: Executive Summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines for the management of adults with congenital heart disease). View Abstract
ACC/AHA 2008 Guidelines for the Management of Adults with Congenital Heart Disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to develop guidelines on the management of adults with congenital heart disease). View Abstract
Sudden death and defibrillators in transposition of the great arteries with intra-atrial baffles: a multicenter study. View Abstract
Multicenter research in adult congenital heart disease. View Abstract
Adult congenital heart disease: toward prospective risk assessment of a multisystemic condition. View Abstract
Trends in the use of percutaneous closure of patent foramen ovale and atrial septal defect in adults, 1998-2004. View Abstract
Implantable cardioverter-defibrillators in tetralogy of Fallot. View Abstract
Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery. View Abstract
Transcatheter closure of high-risk muscular ventricular septal defects with the CardioSEAL occluder: initial report from the CardioSEAL VSD registry. View Abstract
Longer-term bosentan therapy improves functional capacity in Eisenmenger syndrome: results of the BREATHE-5 open-label extension study. View Abstract
Pulmonary thrombectomy in a patient with hemoglobin Nottingham. View Abstract
Interventional catheterization in adult congenital heart disease. View Abstract
Congenital heart disease associated pulmonary arterial hypertension. View Abstract
Acute and intermediate outcomes, and evaluation of injury to the aortic wall, as based on 15 years experience of implanting stents to treat aortic coarctation. View Abstract
Cardiac troponin increases among runners in the Boston Marathon. View Abstract
Ventricular size and function assessed by cardiac MRI predict major adverse clinical outcomes late after tetralogy of Fallot repair. View Abstract
Pregnancy outcomes after atrial repair for transposition of the great arteries. View Abstract
Pulmonary arterial embolization of pacemaker lead electrode tip. View Abstract
Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. View Abstract
Pediatric cardiology and adult congenital heart disease. View Abstract
Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study. View Abstract
Pregnancy outcomes in women with congenital heart disease. View Abstract
Report of the National Heart, Lung, and Blood Institute Working Group on research in adult congenital heart disease. View Abstract
Pediatric cardiology and congenital heart disease. View Abstract
Postinfarction ventricular septal defect with pseudoaneurysm repair after failed percutaneous closure. View Abstract
Transitioning the young adult with congenital heart disease for life-long medical care. View Abstract
Transcatheter intracardiac device implantation for atrial level defects and thrombosis: a call for randomized, controlled data. View Abstract
Elevated basic fibroblast growth factor levels in patients with pulmonary arterial hypertension. View Abstract
Transcatheter device closure of congenital and postoperative residual ventricular septal defects. View Abstract
Long-term outcomes after the atrial switch for surgical correction of transposition: a meta-analysis comparing the Mustard and Senning procedures. View Abstract
Value of programmed ventricular stimulation after tetralogy of fallot repair: a multicenter study. View Abstract
Indications for the closure of patent foramen ovale. View Abstract
Transcatheter closure versus medical therapy of patent foramen ovale and presumed paradoxical thromboemboli: a systematic review. View Abstract
Usefulness of epoprostenol therapy in the severely ill adolescent/adult with Eisenmenger physiology. View Abstract
Depression and anxiety in adults with congenital heart disease: a pilot study. View Abstract
Paradoxic cerebral embolism after cemented knee arthroplasty: a report of 2 cases and prophylactic option for subsequent arthroplasty. View Abstract
Gadolinium-enhanced 3-dimensional magnetic resonance angiography of pulmonary blood supply in patients with complex pulmonary stenosis or atresia: comparison with x-ray angiography. View Abstract
Bosentan therapy for pulmonary arterial hypertension. View Abstract
Vasoresponsiveness of sarcoidosis-associated pulmonary hypertension. View Abstract
Catheterization of the adult with congenital heart disease (ACHD): beyond "shooting the coronaries". View Abstract
Percutaneous coronary intervention and subsequent endovascular beta-radiation brachytherapy in a 14-year-old with repaired anomalous left coronary artery from pulmonary artery. View Abstract
Multi atrial maco-re-entry circuits in adults with repaired congenital heart disease: entrainment mapping combined with three-dimensional electroanatomic mapping. View Abstract
Closure of atrial septal defects in adult patients: justification of the "tipping point". View Abstract
Task force 4: organization of delivery systems for adults with congenital heart disease. View Abstract
Balloon pulmonary angioplasty for treatment of chronic thromboembolic pulmonary hypertension. View Abstract
Accuracy of MRI evaluation of pulmonary blood supply in patients with complex pulmonary stenosis or atresia. View Abstract
Closure of patent foramen ovale for paradoxical emboli: intermediate-term risk of recurrent neurological events following transcatheter device placement. View Abstract
Inhaled nitric oxide therapy in pregnancy complicated by pulmonary hypertension. View Abstract
In vivo evaluation of Fontan pathway flow dynamics by multidimensional phase-velocity magnetic resonance imaging. View Abstract
Transcatheter management of ventricular septal rupture after myocardial infarction. View Abstract
Isolated peripheral pulmonary artery stenoses in the adult. View Abstract
Long-term follow-up after surgical repair of ostium primum atrial septal defects in adults. View Abstract
Role of nitric oxide in the local regulation of pulmonary vascular resistance in humans. View Abstract
Orthodeoxia-platypnea due to intracardiac shunting--relief with transcatheter double umbrella closure. View Abstract
Coronary artery abnormalities detected at cardiac catheterization following the arterial switch operation for transposition of the great arteries. View Abstract
Inhaled nitric oxide and hemodynamic evaluation of patients with pulmonary hypertension before transplantation. View Abstract
Balloon aortic valvuloplasty in the young adult with congenital aortic stenosis. View Abstract
Interventional catheter procedures used in congenital heart disease. View Abstract
Inhaled nitric oxide in chronic obstructive lung disease. View Abstract
Transcatheter closure of cardiac defects. View Abstract
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