Sleep-disordered breathing, mostly commonly obstructive sleep apnea (OSA), peaks at ages 3 to 6, when the tonsils and adenoids are at their largest size relative to the upper airway, and then again during adolescence, often concurrent with overweight and obesity.
The prevalence of OSA is up to 4 percent in all children and even higher in children who have low muscle tone, craniofacial abnormalities, neuromuscular disorders, certain chromosomal variantsm, or who are obese. Common signs and symptoms of OSA include snoring, witnessed pauses in breathing, gasping, or snorting, and mouth breathing. Night sweats, sleeping with the neck hyperextended and reemergence of bedwetting (due to increased nighttime urine production) also can be signs of OSA.
OSA leads to fragmented sleep and is associated with excessive daytime sleepiness in older children. Younger children tend to present more commonly with symptoms of attentional deficit or hyperactivity. An estimated 25 percent of children with ADHD have OSA, and the attention and behavioral symptoms often improve after the OSA is treated.
When there is clinical concern for OSA, an overnight sleep study is the diagnostic gold standard. The first line of therapy for OSA is usually removal of the tonsils and adenoids. Nasal steroids such as montelukast are sometimes used as well in milder cases.
Continuous positive airway pressure (CPAP), if the child can tolerate it, is usually the next treatment choice for OSA, and it can dramatically improve daytime symptoms. CPAP, too, is palliative rather than curative. The optimal pressure settings can change over time, requiring adjustments. Other treatment options include orthodontic interventions such as maxillary expansion, and weight loss as a long-term strategy.
Other, less common medical causes of disordered sleep include restless legs syndrome and narcolepsy.